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The map label for this gene is malE [C]

Identifier: 124023230

GI number: 124023230

Start: 1331545

End: 1332813

Strand: Direct

Name: malE [C]

Synonym: P9303_15281

Alternate gene names: 124023230

Gene position: 1331545-1332813 (Clockwise)

Preceding gene: 124023229

Following gene: 124023231

Centisome position: 49.63

GC content: 46.41

Gene sequence:

>1269_bases
ATGAAGAGAAGGACATTTTGGAAAATAGCTCTGCTGTTCTCTTTGACTAGCGTTGCACTATTTGCAAGCTGGGCCCTGAG
CACTCGCCCTGTTCAGATCAACATCTTAATGCCAGCTCCATTTGCTGAGTCAACAACTGATCTAGTCCAAAAATTCAACA
AAGATCATCACGGCAGTATCCAACTTCAGGTGACTCGAGGTCCACTTGAAACAGAAGCAGTATCGGATTTAGCCATCAGC
AGTCTTCTTTTAGGTAAAAGTCCATTCGATGCACTTTTAATTGATGTCACTTGGTTGCCGAAATACGCCGCCGCAGGATG
GCTTATTCCCTTGGATCCATGGATCGATCAACAACAGATTGATTCCATTGCTCCGGGGGCAATGCTTGGAAATAATTTCG
ACGGGAAACTGTATCGATGGCCACTTGTGGCTGACATGGGATTGCTTTATTGGCGGACAGATTTGATGAGTGAACCACCG
CGTACCCCTGAGGAACTCATTAAAGTTAGTCTTAAGCTCCAAAAAGAAGGCCGTATTGCTTTTGGCTATGTCTGGCAAGG
CCGTCAATATGAAGGCCTAAGTTGTGTATTTCTAGAAGTTCTTGACGGATTTGGAGGACAATGGCTTGAACCCGAAACCG
ATAATGTTGGCCTCGACAGCTCCGCAAGTCTTCAGGCTGCAAGTTGGTTGCGTGAACTGATCAGCAGTGGAGTGAGCCCC
GAAGCAGTGATCAACTATGCCGAAAATGAAACTCTTCAAGCCTTTAAGTCTGGAGATGTTGCGCTAATGCGTAACTGGCC
TTATGCCTGGGGAGAACTGCAGAAGCCTAACAGCGATGTTAGAGGCAATGTTGGAGTAACCACGATGGTTGCTACCGCTG
CCAATCGATCCACATCAACCCTAGGCAGCTGGGGCTTCTCGATCCTCAAGGGCTCATCTAATCCTCAAGCTGCAGCAGAG
GCCATTGCCTTCCTCACATCAACATCTGCACAAAAAAGACTGTTCTTGAACGACAGCTATACCCCAACTAAAGCAGAACT
ATTTAAAGACCCAGAACTGCTCTCAAAATCACAAATTCTTCCGGAGCTTGCTAATGCCCTACAAAGCACTGATCAACGTC
CAGCAACCCCTCTATATGCACAGATTAGTGATGTACTACAACGAAATCTGAGTTCAATTTTTACAGGCCAATCCACCGTT
AGCGATGCAATGTCCAACGCCCAAGCAAACACCAAGAAGATTCTTATGGCGGCAAGAGAAACTAAATGA

Upstream 100 bases:

>100_bases
ACAATGTGATAACGATTGCTATTGTTGACTCATGCACAGTCAAGGATTGGCCAGAAGAGCAAATGAAAAGTTTGGTTGAT
AAAATAGAAGCTACGCAACC

Downstream 100 bases:

>100_bases
TCCAATTGCTTCTATTCCCGGCAGCTCTATTAATTGCCTTCGTCTTTGGTATCCCTCTACTTCGTTATTCCTGGTTGAGC
TTCCATGCTGATTCAGTCCT

Product: sugar ABC transporter substrate-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKRRTFWKIALLFSLTSVALFASWALSTRPVQINILMPAPFAESTTDLVQKFNKDHHGSIQLQVTRGPLETEAVSDLAIS
SLLLGKSPFDALLIDVTWLPKYAAAGWLIPLDPWIDQQQIDSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMSEPP
RTPEELIKVSLKLQKEGRIAFGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETDNVGLDSSASLQAASWLRELISSGVSP
EAVINYAENETLQAFKSGDVALMRNWPYAWGELQKPNSDVRGNVGVTTMVATAANRSTSTLGSWGFSILKGSSNPQAAAE
AIAFLTSTSAQKRLFLNDSYTPTKAELFKDPELLSKSQILPELANALQSTDQRPATPLYAQISDVLQRNLSSIFTGQSTV
SDAMSNAQANTKKILMAARETK

Sequences:

>Translated_422_residues
MKRRTFWKIALLFSLTSVALFASWALSTRPVQINILMPAPFAESTTDLVQKFNKDHHGSIQLQVTRGPLETEAVSDLAIS
SLLLGKSPFDALLIDVTWLPKYAAAGWLIPLDPWIDQQQIDSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMSEPP
RTPEELIKVSLKLQKEGRIAFGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETDNVGLDSSASLQAASWLRELISSGVSP
EAVINYAENETLQAFKSGDVALMRNWPYAWGELQKPNSDVRGNVGVTTMVATAANRSTSTLGSWGFSILKGSSNPQAAAE
AIAFLTSTSAQKRLFLNDSYTPTKAELFKDPELLSKSQILPELANALQSTDQRPATPLYAQISDVLQRNLSSIFTGQSTV
SDAMSNAQANTKKILMAARETK
>Mature_422_residues
MKRRTFWKIALLFSLTSVALFASWALSTRPVQINILMPAPFAESTTDLVQKFNKDHHGSIQLQVTRGPLETEAVSDLAIS
SLLLGKSPFDALLIDVTWLPKYAAAGWLIPLDPWIDQQQIDSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMSEPP
RTPEELIKVSLKLQKEGRIAFGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETDNVGLDSSASLQAASWLRELISSGVSP
EAVINYAENETLQAFKSGDVALMRNWPYAWGELQKPNSDVRGNVGVTTMVATAANRSTSTLGSWGFSILKGSSNPQAAAE
AIAFLTSTSAQKRLFLNDSYTPTKAELFKDPELLSKSQILPELANALQSTDQRPATPLYAQISDVLQRNLSSIFTGQSTV
SDAMSNAQANTKKILMAARETK

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46413; Mature: 46413

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRTFWKIALLFSLTSVALFASWALSTRPVQINILMPAPFAESTTDLVQKFNKDHHGSI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEE
QLQVTRGPLETEAVSDLAISSLLLGKSPFDALLIDVTWLPKYAAAGWLIPLDPWIDQQQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCEEECCCCCCHHHH
DSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMSEPPRTPEELIKVSLKLQKEGRIA
HHCCCCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCEE
FGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETDNVGLDSSASLQAASWLRELISSGVSP
EEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
EAVINYAENETLQAFKSGDVALMRNWPYAWGELQKPNSDVRGNVGVTTMVATAANRSTST
HHHEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCH
LGSWGFSILKGSSNPQAAAEAIAFLTSTSAQKRLFLNDSYTPTKAELFKDPELLSKSQIL
HHHCCHHEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHH
PELANALQSTDQRPATPLYAQISDVLQRNLSSIFTGQSTVSDAMSNAQANTKKILMAARE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEEECC
TK
CC
>Mature Secondary Structure
MKRRTFWKIALLFSLTSVALFASWALSTRPVQINILMPAPFAESTTDLVQKFNKDHHGSI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEE
QLQVTRGPLETEAVSDLAISSLLLGKSPFDALLIDVTWLPKYAAAGWLIPLDPWIDQQQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCEEECCCCCCHHHH
DSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMSEPPRTPEELIKVSLKLQKEGRIA
HHCCCCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCEE
FGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETDNVGLDSSASLQAASWLRELISSGVSP
EEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
EAVINYAENETLQAFKSGDVALMRNWPYAWGELQKPNSDVRGNVGVTTMVATAANRSTST
HHHEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCH
LGSWGFSILKGSSNPQAAAEAIAFLTSTSAQKRLFLNDSYTPTKAELFKDPELLSKSQIL
HHHCCHHEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHH
PELANALQSTDQRPATPLYAQISDVLQRNLSSIFTGQSTVSDAMSNAQANTKKILMAARE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEEECC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]