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The map label for this gene is des [H]

Identifier: 124023117

GI number: 124023117

Start: 1208715

End: 1209800

Strand: Direct

Name: des [H]

Synonym: P9303_14121

Alternate gene names: 124023117

Gene position: 1208715-1209800 (Clockwise)

Preceding gene: 124023116

Following gene: 124023118

Centisome position: 45.06

GC content: 41.07

Gene sequence:

>1086_bases
TTGCAACGCAGTGACCCTTGGGCTTGTTGGCAGTTGTTCTCCACTCTTGTTCCGATTGCTGGATTATGGCTGATGGTGTC
ATTGATTGGGCATGCATCCTCTCCAGTTGGCCTGAAGGCTGTTCAATTATTCATTGTTCTTGTCCTGTTGGTTTTGCTGT
CGTCTCGTTGCTTTGCTTTAATGCACGATTGCGGACACGGTTCTCTTTTTAACTCCCGATGGCTCAACCGCTCAGCCGGA
TTTTTTCTTGGAGTGCTGAATGCGATACCTCAGCACCCTTGGTCAAGAGGTCATGCATATCATCATAAGCACAATGGAAA
TTGGCAGCTTTATCGAGGCCCTTCAGCTTTACTAACTCTTGCTCAGTATCAATCTCTATCTAAAATTAACAAGATTATAT
ATTTTATAACTCGGCATCCATTGATGTTATTTCCTGGTGGTTTCTTTTACCTCATAATTAAGCCTCGATTGGCCTTAATC
CTTGGATTAACAGAATATTGTTGGTCTAAGTGCCATCAATTTGTTGTAGGTCTTCGAGATGAGGGCTGGAACAGCATCAA
TAGTTTTCGGTCTCAATTACTGAAGCATCAGTCAAGTTATTGGTATACCTCTGGAGAATTAGCTGATCTTCTGGCAAATA
ACCTCTGCGTACTAGCAACTTGGTTATTAATGAGTCGATGGCTTGGAGTCGGTCTATTTTGGACTTGTTACTCGTTGGTG
ATGACAGCTTCGGCAGCAATCTTTATTTGCATCTTTTTTGTTCAACATAATTTCGAGGGTTCCTATGCTCATGGTAATGA
CGACTGGAGCTACTTTACTGCAGCAATTGAAGGGAGTAGCAATTTAGATATTCCACTATGGCTTAATTGGTTTTTTGCAG
ATATTTCTTTCCACAGTATTCATCATCTTTGCGAGCGGATTCCTAATTATAGATTGAAGGCATGCCATACACATAATAAA
GCACTTCTGCATGGCGCAAAGAAATTACGCATTACAGAGATACCAGATTGTTTTGCTTATATTCTTTGGGACTCAGACTC
CAATAAGTTAGTCACACTTGCAGATGCAAATCTACAATCTGTTTGA

Upstream 100 bases:

>100_bases
CACTCCAAGCGTTAGCCAGATCCCAACACAATCCTACGATCCACCAATCCCACCAGAGAACAGGCCTCTAAACAGGACTG
ATTTCGTCATAGAGCCCTAC

Downstream 100 bases:

>100_bases
CTAGTCCATCTTAAACGTAGATAATCTATTTGCTTTCACCACAATCAAAATAGAAACTGTTTTGAAATCTAATAATCTGG
TGTTACGGTAACTAAAACGG

Product: Fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQRSDPWACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQLFIVLVLLVLLSSRCFALMHDCGHGSLFNSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQLYRGPSALLTLAQYQSLSKINKIIYFITRHPLMLFPGGFFYLIIKPRLALI
LGLTEYCWSKCHQFVVGLRDEGWNSINSFRSQLLKHQSSYWYTSGELADLLANNLCVLATWLLMSRWLGVGLFWTCYSLV
MTASAAIFICIFFVQHNFEGSYAHGNDDWSYFTAAIEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHTHNK
ALLHGAKKLRITEIPDCFAYILWDSDSNKLVTLADANLQSV

Sequences:

>Translated_361_residues
MQRSDPWACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQLFIVLVLLVLLSSRCFALMHDCGHGSLFNSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQLYRGPSALLTLAQYQSLSKINKIIYFITRHPLMLFPGGFFYLIIKPRLALI
LGLTEYCWSKCHQFVVGLRDEGWNSINSFRSQLLKHQSSYWYTSGELADLLANNLCVLATWLLMSRWLGVGLFWTCYSLV
MTASAAIFICIFFVQHNFEGSYAHGNDDWSYFTAAIEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHTHNK
ALLHGAKKLRITEIPDCFAYILWDSDSNKLVTLADANLQSV
>Mature_361_residues
MQRSDPWACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQLFIVLVLLVLLSSRCFALMHDCGHGSLFNSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQLYRGPSALLTLAQYQSLSKINKIIYFITRHPLMLFPGGFFYLIIKPRLALI
LGLTEYCWSKCHQFVVGLRDEGWNSINSFRSQLLKHQSSYWYTSGELADLLANNLCVLATWLLMSRWLGVGLFWTCYSLV
MTASAAIFICIFFVQHNFEGSYAHGNDDWSYFTAAIEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHTHNK
ALLHGAKKLRITEIPDCFAYILWDSDSNKLVTLADANLQSV

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 41211; Mature: 41211

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSDPWACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQLFIVLVLLVLLSSRCFAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MHDCGHGSLFNSRWLNRSAGFFLGVLNAIPQHPWSRGHAYHHKHNGNWQLYRGPSALLTL
HHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEECHHHHHHH
AQYQSLSKINKIIYFITRHPLMLFPGGFFYLIIKPRLALILGLTEYCWSKCHQFVVGLRD
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGWNSINSFRSQLLKHQSSYWYTSGELADLLANNLCVLATWLLMSRWLGVGLFWTCYSLV
CCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MTASAAIFICIFFVQHNFEGSYAHGNDDWSYFTAAIEGSSNLDIPLWLNWFFADISFHSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
HHLCERIPNYRLKACHTHNKALLHGAKKLRITEIPDCFAYILWDSDSNKLVTLADANLQS
HHHHHHCCCCEEEHHHCCCHHHHHCHHHEEEEECCCEEEEEEEECCCCCEEEEECCCCCC
V
C
>Mature Secondary Structure
MQRSDPWACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQLFIVLVLLVLLSSRCFAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MHDCGHGSLFNSRWLNRSAGFFLGVLNAIPQHPWSRGHAYHHKHNGNWQLYRGPSALLTL
HHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEECHHHHHHH
AQYQSLSKINKIIYFITRHPLMLFPGGFFYLIIKPRLALILGLTEYCWSKCHQFVVGLRD
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGWNSINSFRSQLLKHQSSYWYTSGELADLLANNLCVLATWLLMSRWLGVGLFWTCYSLV
CCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MTASAAIFICIFFVQHNFEGSYAHGNDDWSYFTAAIEGSSNLDIPLWLNWFFADISFHSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
HHLCERIPNYRLKACHTHNKALLHGAKKLRITEIPDCFAYILWDSDSNKLVTLADANLQS
HHHHHHCCCCEEEHHHCCCHHHHHCHHHEEEEECCCEEEEEEEECCCCCEEEEECCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]