Click here to switch to the map view.

The map label for this gene is ykuT [H]

Identifier: 124023050

GI number: 124023050

Start: 1151002

End: 1152972

Strand: Direct

Name: ykuT [H]

Synonym: P9303_13451

Alternate gene names: 124023050

Gene position: 1151002-1152972 (Clockwise)

Preceding gene: 124023049

Following gene: 124023052

Centisome position: 42.91

GC content: 42.21

Gene sequence:

>1971_bases
ATGCAGCTACTTTCCAAAAAAAAATTAGGTTTGCGTCGGTTGGTATGTCTTTTTTGTGGCTTACTGATCAGTCTGCTTTT
TTCCCCTGCTTTTGCACAGATCTCGTTGGGGTCAACAGCAGCTCCCATCAGTAATCCTATGAACCGACCTGTCTGGGACC
TTAATAGACCTTGGCGTTGTGGCCGCCTTTACTGCAGCAGAGTTGTTTTTCCTGTTCGAATTCTTAGCCAGAACAATCGT
CTCACTCTCGCTGCGCAAGCTACAAATAAAATTACTCCACAGCAGGCAGCCCAGAACATTGAACAACGAGCTCAATCTGT
ACAGTTAACTGTTAAATCTGTCAAAAATCGTCTTGTTAGGTTCTGGCGAGAGACCCAGTTGTCTGGGAATGCTTCTACTT
ACGATCTACAACGAATCTATGATCCACGCTTCTGGTGGTTCTTACATCAGAAACCTTTGCATCCTCTTACTCCAGCAGTG
GAGATCGGCACACAAAATAAAGCCACAGTTATCTATTTGCCAGACAATCCAAAGTATCGTCTTTTTAAACAGACAGTAAT
TACAGTAACGGCTCCAGATGCTCAGCATGCAGGCATTGAGATCCCTCAGTTGGCGCAAGAGTGGCAGCAGAGAATAAGGG
TCAACTTTAGTGATCGTTTGTGGGGCCTGGAATTTTCCTCCTCCTTTCCTGGATTACGTGTTTTACTTTCTGTCGGCTTG
TTGTTAACAGGCATTTTTGGCTTGTTTCTTCTCAAAACCATACGAGCTTCATTGCTCTCCATAAATCGTCGTTTATTGCA
TAAACAGGAATCACTTGCAGAATCTGTTAAAGACGATGTGATGGCTGCTTATTCGGGCAACCTTATGCCCCTTTCCAATA
ATGACGGACATGTTAATTATATCGATTCACTCGAGCATTCAAAGGATTCATCTGGCGTCGATAATGTCAATGAGTCTACA
ACTCAAGACCCTAATCCAGGCATCAATAATCTTCCTAGATCAGCTACTTATACTAATGCTTTATTGAACCAGACCCAGAA
TTTCCTAGAACTCGTTTTATTAGTAAGTAATTTTCTGCAAATCGCATTTTTAGTCTTAGTCTTGCTTTCTGCTACAGCTG
TTTATCCTTCAATGCGTATATACGCATTTATTGCCCTACAGCAGTCGATTGCGATTCCTTTGATTTGGGTAGGCGTCTTT
ATTTTGCGGCTTTTGGTTGTCATCATGATTGATTTCAATATCAATAATTGGATAAGGCGGATTAGTAGCACAGATGCTAG
TTCGATGCGCTACACGCTTAGGGCAAGTACATACTCTAAGGTTCTTAAAGGTGGAGCAACCGTAATTACAATCTTTCTAG
GTCTCGTTTTTACTTTAACAACAATAGGAGTCGACCGGTCTATTTTTACCAGTGCTGGAGTAATCGCTGTGGGTGTGGGT
TTCCTTTCTCGAAATGTACTTGAGGATATTCTTAACGGATTTCTTATCTTGGCTGGTGATCGTTTTGCAATAGGTGATGT
CGTGACGATCGGCAGCTTTGGTGGCTTTGTTGAAGATATGAATTTATTCAACACTCAACTTCGTGGTTCTGATGGTCAAC
TAACAACTCTGCCTAATAGCCAGATTCGAACCGTAGAGAACCTTACTAAGGATTGGTCTCGAGTTAATTTTGATATCGAG
GTATCAGCTCGCGAGAATCTTCGCCATGTGCTCGATGTGGTTCGGCTTGTAGCCAATAACATGAGAGATGACAAGCAATG
GAGTGATTATTTTCTTGATGCTCCCGAGATCCTTGGTATTGATCATGTGCAATCATCAGGTTGTTTAATCCGTGTTTGGA
TAAAAACTCAACCCTTGGCTCAGTGGAGTGTAGGCCGTGAGTTTAGGTTGCAGATTAAAGAAGCTTTTGACCGGGAGGGA
ATTACACTTGGTGCTCCTATTCAAAATGTGTTATTTTTCCGACCAAAATGA

Upstream 100 bases:

>100_bases
CCAGATCATGCTGAAGGATCAAGCTTTTCCTATTTTTGCTGGCTATCGATCAGCAACTCATTTAATCTAGCTACAATCCT
TAGATGGATAAGAATTGGTA

Downstream 100 bases:

>100_bases
TTAACTTTAACCAAGTTAAATAAATTCTATATCAAAATAATGTTCAGTCAAATGTATCTTTTGCATATGCGATAGTTTGA
GTCTTCTTGAATGTTTAATT

Product: mechanosensitive ion channel, MscS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MQLLSKKKLGLRRLVCLFCGLLISLLFSPAFAQISLGSTAAPISNPMNRPVWDLNRPWRCGRLYCSRVVFPVRILSQNNR
LTLAAQATNKITPQQAAQNIEQRAQSVQLTVKSVKNRLVRFWRETQLSGNASTYDLQRIYDPRFWWFLHQKPLHPLTPAV
EIGTQNKATVIYLPDNPKYRLFKQTVITVTAPDAQHAGIEIPQLAQEWQQRIRVNFSDRLWGLEFSSSFPGLRVLLSVGL
LLTGIFGLFLLKTIRASLLSINRRLLHKQESLAESVKDDVMAAYSGNLMPLSNNDGHVNYIDSLEHSKDSSGVDNVNEST
TQDPNPGINNLPRSATYTNALLNQTQNFLELVLLVSNFLQIAFLVLVLLSATAVYPSMRIYAFIALQQSIAIPLIWVGVF
ILRLLVVIMIDFNINNWIRRISSTDASSMRYTLRASTYSKVLKGGATVITIFLGLVFTLTTIGVDRSIFTSAGVIAVGVG
FLSRNVLEDILNGFLILAGDRFAIGDVVTIGSFGGFVEDMNLFNTQLRGSDGQLTTLPNSQIRTVENLTKDWSRVNFDIE
VSARENLRHVLDVVRLVANNMRDDKQWSDYFLDAPEILGIDHVQSSGCLIRVWIKTQPLAQWSVGREFRLQIKEAFDREG
ITLGAPIQNVLFFRPK

Sequences:

>Translated_656_residues
MQLLSKKKLGLRRLVCLFCGLLISLLFSPAFAQISLGSTAAPISNPMNRPVWDLNRPWRCGRLYCSRVVFPVRILSQNNR
LTLAAQATNKITPQQAAQNIEQRAQSVQLTVKSVKNRLVRFWRETQLSGNASTYDLQRIYDPRFWWFLHQKPLHPLTPAV
EIGTQNKATVIYLPDNPKYRLFKQTVITVTAPDAQHAGIEIPQLAQEWQQRIRVNFSDRLWGLEFSSSFPGLRVLLSVGL
LLTGIFGLFLLKTIRASLLSINRRLLHKQESLAESVKDDVMAAYSGNLMPLSNNDGHVNYIDSLEHSKDSSGVDNVNEST
TQDPNPGINNLPRSATYTNALLNQTQNFLELVLLVSNFLQIAFLVLVLLSATAVYPSMRIYAFIALQQSIAIPLIWVGVF
ILRLLVVIMIDFNINNWIRRISSTDASSMRYTLRASTYSKVLKGGATVITIFLGLVFTLTTIGVDRSIFTSAGVIAVGVG
FLSRNVLEDILNGFLILAGDRFAIGDVVTIGSFGGFVEDMNLFNTQLRGSDGQLTTLPNSQIRTVENLTKDWSRVNFDIE
VSARENLRHVLDVVRLVANNMRDDKQWSDYFLDAPEILGIDHVQSSGCLIRVWIKTQPLAQWSVGREFRLQIKEAFDREG
ITLGAPIQNVLFFRPK
>Mature_656_residues
MQLLSKKKLGLRRLVCLFCGLLISLLFSPAFAQISLGSTAAPISNPMNRPVWDLNRPWRCGRLYCSRVVFPVRILSQNNR
LTLAAQATNKITPQQAAQNIEQRAQSVQLTVKSVKNRLVRFWRETQLSGNASTYDLQRIYDPRFWWFLHQKPLHPLTPAV
EIGTQNKATVIYLPDNPKYRLFKQTVITVTAPDAQHAGIEIPQLAQEWQQRIRVNFSDRLWGLEFSSSFPGLRVLLSVGL
LLTGIFGLFLLKTIRASLLSINRRLLHKQESLAESVKDDVMAAYSGNLMPLSNNDGHVNYIDSLEHSKDSSGVDNVNEST
TQDPNPGINNLPRSATYTNALLNQTQNFLELVLLVSNFLQIAFLVLVLLSATAVYPSMRIYAFIALQQSIAIPLIWVGVF
ILRLLVVIMIDFNINNWIRRISSTDASSMRYTLRASTYSKVLKGGATVITIFLGLVFTLTTIGVDRSIFTSAGVIAVGVG
FLSRNVLEDILNGFLILAGDRFAIGDVVTIGSFGGFVEDMNLFNTQLRGSDGQLTTLPNSQIRTVENLTKDWSRVNFDIE
VSARENLRHVLDVVRLVANNMRDDKQWSDYFLDAPEILGIDHVQSSGCLIRVWIKTQPLAQWSVGREFRLQIKEAFDREG
ITLGAPIQNVLFFRPK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=217, Percent_Identity=25.3456221198157, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 73723; Mature: 73723

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLSKKKLGLRRLVCLFCGLLISLLFSPAFAQISLGSTAAPISNPMNRPVWDLNRPWRC
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCHH
GRLYCSRVVFPVRILSQNNRLTLAAQATNKITPQQAAQNIEQRAQSVQLTVKSVKNRLVR
HHHHHHHHHHHHHEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRETQLSGNASTYDLQRIYDPRFWWFLHQKPLHPLTPAVEIGTQNKATVIYLPDNPKYR
HHHHHCCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCEE
LFKQTVITVTAPDAQHAGIEIPQLAQEWQQRIRVNFSDRLWGLEFSSSFPGLRVLLSVGL
EEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECEECCCCCCHHHHHHHHHH
LLTGIFGLFLLKTIRASLLSINRRLLHKQESLAESVKDDVMAAYSGNLMPLSNNDGHVNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
IDSLEHSKDSSGVDNVNESTTQDPNPGINNLPRSATYTNALLNQTQNFLELVLLVSNFLQ
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFLVLVLLSATAVYPSMRIYAFIALQQSIAIPLIWVGVFILRLLVVIMIDFNINNWIRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISSTDASSMRYTLRASTYSKVLKGGATVITIFLGLVFTLTTIGVDRSIFTSAGVIAVGVG
HHCCCCCCEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHH
FLSRNVLEDILNGFLILAGDRFAIGDVVTIGSFGGFVEDMNLFNTQLRGSDGQLTTLPNS
HHHHHHHHHHHCCEEEEECCCEEECCEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCH
QIRTVENLTKDWSRVNFDIEVSARENLRHVLDVVRLVANNMRDDKQWSDYFLDAPEILGI
HHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCC
DHVQSSGCLIRVWIKTQPLAQWSVGREFRLQIKEAFDREGITLGAPIQNVLFFRPK
CCCCCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHCCCCCEECCCHHHCEEECCC
>Mature Secondary Structure
MQLLSKKKLGLRRLVCLFCGLLISLLFSPAFAQISLGSTAAPISNPMNRPVWDLNRPWRC
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCHH
GRLYCSRVVFPVRILSQNNRLTLAAQATNKITPQQAAQNIEQRAQSVQLTVKSVKNRLVR
HHHHHHHHHHHHHEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRETQLSGNASTYDLQRIYDPRFWWFLHQKPLHPLTPAVEIGTQNKATVIYLPDNPKYR
HHHHHCCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCEE
LFKQTVITVTAPDAQHAGIEIPQLAQEWQQRIRVNFSDRLWGLEFSSSFPGLRVLLSVGL
EEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECEECCCCCCHHHHHHHHHH
LLTGIFGLFLLKTIRASLLSINRRLLHKQESLAESVKDDVMAAYSGNLMPLSNNDGHVNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
IDSLEHSKDSSGVDNVNESTTQDPNPGINNLPRSATYTNALLNQTQNFLELVLLVSNFLQ
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFLVLVLLSATAVYPSMRIYAFIALQQSIAIPLIWVGVFILRLLVVIMIDFNINNWIRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISSTDASSMRYTLRASTYSKVLKGGATVITIFLGLVFTLTTIGVDRSIFTSAGVIAVGVG
HHCCCCCCEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHH
FLSRNVLEDILNGFLILAGDRFAIGDVVTIGSFGGFVEDMNLFNTQLRGSDGQLTTLPNS
HHHHHHHHHHHCCEEEEECCCEEECCEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCH
QIRTVENLTKDWSRVNFDIEVSARENLRHVLDVVRLVANNMRDDKQWSDYFLDAPEILGI
HHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCC
DHVQSSGCLIRVWIKTQPLAQWSVGREFRLQIKEAFDREGITLGAPIQNVLFFRPK
CCCCCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHCCCCCEECCCHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]