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The map label for this gene is sbcD [C]

Identifier: 124023034

GI number: 124023034

Start: 1135688

End: 1136902

Strand: Direct

Name: sbcD [C]

Synonym: P9303_13291

Alternate gene names: 124023034

Gene position: 1135688-1136902 (Clockwise)

Preceding gene: 124023026

Following gene: 124023035

Centisome position: 42.33

GC content: 51.19

Gene sequence:

>1215_bases
TTGCCCCGATTTCTTCACACCGCTGACTGGCAAATCGGCAAGCCCTTTAGGAATATCACAGATCCTCAGAAGCGCTTTCG
CCTGCAACAGCAGCGGATCTTGTCTGTTTCACGGATCGCTGCTGTTGCCGAAGAGCACAACGTTGATGCCGTGCTGGTGG
CAGGCGATCTGTTCGATTCCAGCACCGTCCCATCAGCTGTGGTGATGGAGGTCTTGGAGGTGATTGGTTCTATGAATCGT
CCAGTCCTGGTGATCCCGGGCAATCATGACCATGGTGGAGCTGGAGGTGTTTGGCAGCGCCAGGATGTTCAAAGGCAGTT
GAAAGAACGCGCACCCTTGATGCAGTTGCTTCTTAAACCGGAGCCGGTTTTGATTGATCATGCGTTTGTTTTGCCTTGCC
CTCTGCTACGTCAGCGCGATAGCGAAGACCCCTCAGCTTGGATTAGTCAGCTGGATTGGCAGGATCTAGCTGAAGATTGT
CCTCGAATTGTTCTTGCACATGGAGCTGTGCACGGATTCGAGAGCACTGATTACAACCAAGACAGTGCTGGTCAGTCGGA
GCGGATCAACCGCATTGATCTTGACATGATCCAACATGGGCAGGTTGATTACGTCGCTCTTGGCGACTGGCACAATCTCA
AACAAGTAGGAGATCGTGCTTGGTATTGCGGAACCCCTGAACCGGATCGCTTTGATCAGGGGGACCAGGACCAGCGTGGG
CAGGTTTTAGTGTTTGATATCGATCGAGGGACATGTCCCATCCCGAAGTCTGTTTCAACGGCTGGGTTGCACTGGCACAA
TCTTCGGGTACAGCTCAGAACCACTAGCGATCTTGATCGACTGGAGCGGACTCTCCAGCAGCGCATTGGAAGTCGAGTAG
GCCGTGATCTATTGAGGCTGGAAATTAATGGACAACTGAGTCTTCGTGAGTATCAACGCTTTGATGCCTTAATCGAGGTG
CTAAGGACGCAATTGCTGCATGTACGCATCAAAGGAACCTGCCATCGACGTCCAGGTCAGGAAGAACTTCGGGCCATGAC
TGATCGCAGTGAAGATCATTTGATTAGTTCTATTGCCTTACAACTACAAGGAGAACTTGAAAACCTTGAACCTACCAAAC
CTCTTACAACTGAACAGCAGAGCGAAGCCGAGCTGATCGAGTTAGCTCTTTGTGAACTCCATCGGCTTTGCAGTGAGTCA
TCCTTGAATAACTGA

Upstream 100 bases:

>100_bases
GACACACTTTTAGGGCCACTTTGCCAAGTTGATCTCCCCTGAGGGGGCTTCAGAAATAGAAGAGTCACGGCAGCATGGGG
ACCCGGAGTGTGTTTCAGCT

Downstream 100 bases:

>100_bases
TCGCCCTATGCGCTTATTGCACTGCCATCTTGAAAATATTCGCCGTCATTGGCTCTTGGATATCGACTTTTCGCCCGGAT
TGACGTTGATTTCTGGAGCC

Product: DNA repair exonuclease

Products: NA

Alternate protein names: DNA Repair Exonuclease; Exonuclease; Exonuclease SbcD; Ser/Thr Protein Phosphatase Family Protein; Exodeoxyribonuclease I Subunit D; Exonuclease SbcD Family Protein; Nuclease SbcCD D Subunit; Calcineurin-Like Phosphoesterase Family; DNA Repair Exonuclease Or Phosphoesterase

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MPRFLHTADWQIGKPFRNITDPQKRFRLQQQRILSVSRIAAVAEEHNVDAVLVAGDLFDSSTVPSAVVMEVLEVIGSMNR
PVLVIPGNHDHGGAGGVWQRQDVQRQLKERAPLMQLLLKPEPVLIDHAFVLPCPLLRQRDSEDPSAWISQLDWQDLAEDC
PRIVLAHGAVHGFESTDYNQDSAGQSERINRIDLDMIQHGQVDYVALGDWHNLKQVGDRAWYCGTPEPDRFDQGDQDQRG
QVLVFDIDRGTCPIPKSVSTAGLHWHNLRVQLRTTSDLDRLERTLQQRIGSRVGRDLLRLEINGQLSLREYQRFDALIEV
LRTQLLHVRIKGTCHRRPGQEELRAMTDRSEDHLISSIALQLQGELENLEPTKPLTTEQQSEAELIELALCELHRLCSES
SLNN

Sequences:

>Translated_404_residues
MPRFLHTADWQIGKPFRNITDPQKRFRLQQQRILSVSRIAAVAEEHNVDAVLVAGDLFDSSTVPSAVVMEVLEVIGSMNR
PVLVIPGNHDHGGAGGVWQRQDVQRQLKERAPLMQLLLKPEPVLIDHAFVLPCPLLRQRDSEDPSAWISQLDWQDLAEDC
PRIVLAHGAVHGFESTDYNQDSAGQSERINRIDLDMIQHGQVDYVALGDWHNLKQVGDRAWYCGTPEPDRFDQGDQDQRG
QVLVFDIDRGTCPIPKSVSTAGLHWHNLRVQLRTTSDLDRLERTLQQRIGSRVGRDLLRLEINGQLSLREYQRFDALIEV
LRTQLLHVRIKGTCHRRPGQEELRAMTDRSEDHLISSIALQLQGELENLEPTKPLTTEQQSEAELIELALCELHRLCSES
SLNN
>Mature_403_residues
PRFLHTADWQIGKPFRNITDPQKRFRLQQQRILSVSRIAAVAEEHNVDAVLVAGDLFDSSTVPSAVVMEVLEVIGSMNRP
VLVIPGNHDHGGAGGVWQRQDVQRQLKERAPLMQLLLKPEPVLIDHAFVLPCPLLRQRDSEDPSAWISQLDWQDLAEDCP
RIVLAHGAVHGFESTDYNQDSAGQSERINRIDLDMIQHGQVDYVALGDWHNLKQVGDRAWYCGTPEPDRFDQGDQDQRGQ
VLVFDIDRGTCPIPKSVSTAGLHWHNLRVQLRTTSDLDRLERTLQQRIGSRVGRDLLRLEINGQLSLREYQRFDALIEVL
RTQLLHVRIKGTCHRRPGQEELRAMTDRSEDHLISSIALQLQGELENLEPTKPLTTEQQSEAELIELALCELHRLCSESS
LNN

Specific function: Sbccd Cleaves DNA Hairpin Structures. These Structures Can Inhibit DNA Replication And Are Intermediates In Certain DNA Recombination Reactions. The Complex Acts As A 3'->5' Double Strand Exonuclease That Can Open Hairpins. It Also Has A 5' Single-Strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786598, Length=277, Percent_Identity=25.9927797833935, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45915; Mature: 45783

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFLHTADWQIGKPFRNITDPQKRFRLQQQRILSVSRIAAVAEEHNVDAVLVAGDLFDS
CCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
STVPSAVVMEVLEVIGSMNRPVLVIPGNHDHGGAGGVWQRQDVQRQLKERAPLMQLLLKP
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCC
EPVLIDHAFVLPCPLLRQRDSEDPSAWISQLDWQDLAEDCPRIVLAHGAVHGFESTDYNQ
CCEEEECHHHCCCHHHHCCCCCCHHHHHHHCCHHHHHHHCCCEEEHHCCCCCCCCCCCCC
DSAGQSERINRIDLDMIQHGQVDYVALGDWHNLKQVGDRAWYCGTPEPDRFDQGDQDQRG
CCCCCHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCC
QVLVFDIDRGTCPIPKSVSTAGLHWHNLRVQLRTTSDLDRLERTLQQRIGSRVGRDLLRL
CEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEE
EINGQLSLREYQRFDALIEVLRTQLLHVRIKGTCHRRPGQEELRAMTDRSEDHLISSIAL
EECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHH
QLQGELENLEPTKPLTTEQQSEAELIELALCELHRLCSESSLNN
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRFLHTADWQIGKPFRNITDPQKRFRLQQQRILSVSRIAAVAEEHNVDAVLVAGDLFDS
CCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
STVPSAVVMEVLEVIGSMNRPVLVIPGNHDHGGAGGVWQRQDVQRQLKERAPLMQLLLKP
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCC
EPVLIDHAFVLPCPLLRQRDSEDPSAWISQLDWQDLAEDCPRIVLAHGAVHGFESTDYNQ
CCEEEECHHHCCCHHHHCCCCCCHHHHHHHCCHHHHHHHCCCEEEHHCCCCCCCCCCCCC
DSAGQSERINRIDLDMIQHGQVDYVALGDWHNLKQVGDRAWYCGTPEPDRFDQGDQDQRG
CCCCCHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCC
QVLVFDIDRGTCPIPKSVSTAGLHWHNLRVQLRTTSDLDRLERTLQQRIGSRVGRDLLRL
CEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEE
EINGQLSLREYQRFDALIEVLRTQLLHVRIKGTCHRRPGQEELRAMTDRSEDHLISSIAL
EECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHH
QLQGELENLEPTKPLTTEQQSEAELIELALCELHRLCSESSLNN
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA