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The map label for this gene is adcA [H]

Identifier: 124022821

GI number: 124022821

Start: 997333

End: 998307

Strand: Reverse

Name: adcA [H]

Synonym: P9303_11141

Alternate gene names: 124022821

Gene position: 998307-997333 (Counterclockwise)

Preceding gene: 124022825

Following gene: 124022820

Centisome position: 37.21

GC content: 45.74

Gene sequence:

>975_bases
TTGTTCAGTTTTTTCTTCTCAAGTCGGCTTAAGCGCCGGTTGTGCTCCTCCATCTTGAAGCTGAGCTCCGCCTCGTTAAT
TCTCAGCTTGGTCGCCTGTGGTGCGTCTGCTCCAACGGAGACCAATTCAAAGGTAAGCAATGGTCTGAAGGTTGTTACGT
CCTTCCTGCCAATGACGCTCTTCACATCCGCTGTAGCAGGAGATTGCGCGACTGTTACTGCCCTCATCCCACCCAATCTT
GGGCCACATGATTTTCAGGCAACGCCAGCTTCGATCTCCTCACTGAGAGAAGCTCAGTTGCTCGTCAAAAACGGCCTAGG
AATGGAAGAATTTCTCGAGAAGTTGCTGACATCTGCTAACAATCCAACACTTGTAGTAATTGATACAAGTGTTGGCATTC
CAACTCTCGAGCCGTCAGTAGATGACACTCACGACCACAATCACGACCACGGTGTGATCAATCCCCACATCTGGCTTGAT
CCAATCAGAGCCATTCAACAAGTTGAGAGTATCCGTGATGGTTTGGTAAAGGCTGACCCAAGTTGTGCTGAGCAATATAA
AAGGAATTCTGAACTATACACTCAAGAACTTCAAAAATTAAATGAGGAGATCTCAGGTCAACTAAAACAATATTCGGGAA
AAACATTTGTTGCCTTCCATGACTTTGCGCCATATTTTGCTGAGAGATACAACCTTAAGGGCGAGTACATCGTTGATCTA
CCTGAAATGAATCCGAGCCCTGCTGATCTACAACGTGTTGCAGTAAAAGTAAGAAAATCTCAACTCAAAGCTCTGCTTAG
TGAGCCTCAGGCAGGAAATCGTTCGTTTAATGCTCTTGCGAATGATCTTGGAGTAAGAGTGGTTGAATTTAATCCACTGG
AAACTGGCTCAATCGATTCAGCGCGTGAGCCTGAGACCTATTTCGATGTCATGAGATCTAATACGGTAAACCTGATTAAG
GCAATCGGGGGCTAA

Upstream 100 bases:

>100_bases
ACAGTCATGCATAAAAATAAAAACTAAACTTAATCCCTTTGACGCAAAGGCGTGAGAATGATTATCATTCTTAAGAATTC
CTGGTTAGCGCCAAGCCGTT

Downstream 100 bases:

>100_bases
TTTTTGATCGTGAGCCCTGTTCTTATAGTAAGAAATCTATGCGTTGAGCGAGCCGGGAGTCTCACAGTTGAGGACGTCTC
ATTCGAATTACATCCTGAAA

Product: hypothetical protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFSFFFSSRLKRRLCSSILKLSSASLILSLVACGASAPTETNSKVSNGLKVVTSFLPMTLFTSAVAGDCATVTALIPPNL
GPHDFQATPASISSLREAQLLVKNGLGMEEFLEKLLTSANNPTLVVIDTSVGIPTLEPSVDDTHDHNHDHGVINPHIWLD
PIRAIQQVESIRDGLVKADPSCAEQYKRNSELYTQELQKLNEEISGQLKQYSGKTFVAFHDFAPYFAERYNLKGEYIVDL
PEMNPSPADLQRVAVKVRKSQLKALLSEPQAGNRSFNALANDLGVRVVEFNPLETGSIDSAREPETYFDVMRSNTVNLIK
AIGG

Sequences:

>Translated_324_residues
MFSFFFSSRLKRRLCSSILKLSSASLILSLVACGASAPTETNSKVSNGLKVVTSFLPMTLFTSAVAGDCATVTALIPPNL
GPHDFQATPASISSLREAQLLVKNGLGMEEFLEKLLTSANNPTLVVIDTSVGIPTLEPSVDDTHDHNHDHGVINPHIWLD
PIRAIQQVESIRDGLVKADPSCAEQYKRNSELYTQELQKLNEEISGQLKQYSGKTFVAFHDFAPYFAERYNLKGEYIVDL
PEMNPSPADLQRVAVKVRKSQLKALLSEPQAGNRSFNALANDLGVRVVEFNPLETGSIDSAREPETYFDVMRSNTVNLIK
AIGG
>Mature_324_residues
MFSFFFSSRLKRRLCSSILKLSSASLILSLVACGASAPTETNSKVSNGLKVVTSFLPMTLFTSAVAGDCATVTALIPPNL
GPHDFQATPASISSLREAQLLVKNGLGMEEFLEKLLTSANNPTLVVIDTSVGIPTLEPSVDDTHDHNHDHGVINPHIWLD
PIRAIQQVESIRDGLVKADPSCAEQYKRNSELYTQELQKLNEEISGQLKQYSGKTFVAFHDFAPYFAERYNLKGEYIVDL
PEMNPSPADLQRVAVKVRKSQLKALLSEPQAGNRSFNALANDLGVRVVEFNPLETGSIDSAREPETYFDVMRSNTVNLIK
AIGG

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=257, Percent_Identity=25.6809338521401, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35482; Mature: 35482

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFFFSSRLKRRLCSSILKLSSASLILSLVACGASAPTETNSKVSNGLKVVTSFLPMTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTSAVAGDCATVTALIPPNLGPHDFQATPASISSLREAQLLVKNGLGMEEFLEKLLTSAN
HHHHHHCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NPTLVVIDTSVGIPTLEPSVDDTHDHNHDHGVINPHIWLDPIRAIQQVESIRDGLVKADP
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
SCAEQYKRNSELYTQELQKLNEEISGQLKQYSGKTFVAFHDFAPYFAERYNLKGEYIVDL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCEEEEC
PEMNPSPADLQRVAVKVRKSQLKALLSEPQAGNRSFNALANDLGVRVVEFNPLETGSIDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCCC
AREPETYFDVMRSNTVNLIKAIGG
CCCCHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MFSFFFSSRLKRRLCSSILKLSSASLILSLVACGASAPTETNSKVSNGLKVVTSFLPMTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTSAVAGDCATVTALIPPNLGPHDFQATPASISSLREAQLLVKNGLGMEEFLEKLLTSAN
HHHHHHCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NPTLVVIDTSVGIPTLEPSVDDTHDHNHDHGVINPHIWLDPIRAIQQVESIRDGLVKADP
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
SCAEQYKRNSELYTQELQKLNEEISGQLKQYSGKTFVAFHDFAPYFAERYNLKGEYIVDL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCEEEEC
PEMNPSPADLQRVAVKVRKSQLKALLSEPQAGNRSFNALANDLGVRVVEFNPLETGSIDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCCC
AREPETYFDVMRSNTVNLIKAIGG
CCCCHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]