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The map label for this gene is gap3 [H]

Identifier: 124022812

GI number: 124022812

Start: 987357

End: 988412

Strand: Direct

Name: gap3 [H]

Synonym: P9303_11051

Alternate gene names: 124022812

Gene position: 987357-988412 (Clockwise)

Preceding gene: 124022808

Following gene: 124022813

Centisome position: 36.8

GC content: 44.89

Gene sequence:

>1056_bases
ATGGCCAAGCAAGGGCCAATGCGTATTGGCATCAACGGTTTTGGACGTATCGGGCGGCTGGTCTTTCGGGCTCTTTGGGG
GAGACCAGGGATCGAGATCTGCCATGTGAACGACCCATCTGGGGAGGCTGCCACTGCAGCACACCTGCTTGAGTTCGATT
CTGTACACGGCCGCTGGGATCAGCTTGTTGGCGGCAGCGAGAACCAACTGTTGGTGAATCAACAAACCATTAGTTACTCC
CAAGGAAGCACTCCTGGCGCTGTGCCTTGGAATGACGCTGGCATTGACATCGTTTTGGAATGCAGCGGTAAATTTAAATC
ACCAGAAACTCTCAGCGTTTACTTCGATCAACATGCTTTAAAACGTGTGATTGTTGCTTGCCCAGTTAAAGGAAAACTAG
CTGGCAAAGAAGTGTTGAATATCGTTTATGGGATCAATCATCATCTTTATGACCCAAAGATTGATCATTTAGTGACAGCA
GCATCATGTACGACAAACTGTTTGGCTCCGTTGGTAAAGGTGGTGCATGAAAACTTTGGTATTTCACATGGCTCCATAAC
AACTCTTCATGATATTACTAACACACAAGTTCCGATTGATAGCTTCCAAAAGGACTTACGTAGGGCTAGGAGTTGTCTAC
AAAGTCTGATCCCAACGACGACAGGCTCTGCCAAAGCAATCGCAATGATCTTTCCAGATCTAGAGGGAAAACTCAATGGA
CATGCTGTAAGAGTACCTTTGCTCAATGCTTCATTGACCGATGCAGTTTTTGAGCTAAAGCGCTCAATTACGGTGAAGGA
TGCCAATGAAGCGTTTAGGCATGCAGCAGAACATCAGCTAAAGGGAATCCTTGGCTATGAAGACAAGCCTCTTGTCTCTA
TTGATTACGTTAACGATTCTCGAAGCTCAATTATCGATGGATTATCAACGATGGTTGTTAACGGCTCTCAGCTAAAGGTT
TACGCATGGTACGACAATGAATGGGGATATAGCAGTCGAATGGCAGATCTTACGTGTTATATTTCTAATCTTGAAAATAC
TAGTAATACCTTTTAA

Upstream 100 bases:

>100_bases
TTAATGGAAGAGGTTTTTTACTTTAAGGACAATATAAGAAAGGGGAAAGAGCGCTTATATCGACTATGGTTGATGCATCA
AGATATTTTGATTGATCCTT

Downstream 100 bases:

>100_bases
ATGATGCTTTCGCCTCTCAATCAATATGGTGTTGTAACCACAAACTACTGGGCCTTTACGCTCACTGATGGTGCATTACG
TATGCTTGTGGTTTTTCACT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAKQGPMRIGINGFGRIGRLVFRALWGRPGIEICHVNDPSGEAATAAHLLEFDSVHGRWDQLVGGSENQLLVNQQTISYS
QGSTPGAVPWNDAGIDIVLECSGKFKSPETLSVYFDQHALKRVIVACPVKGKLAGKEVLNIVYGINHHLYDPKIDHLVTA
ASCTTNCLAPLVKVVHENFGISHGSITTLHDITNTQVPIDSFQKDLRRARSCLQSLIPTTTGSAKAIAMIFPDLEGKLNG
HAVRVPLLNASLTDAVFELKRSITVKDANEAFRHAAEHQLKGILGYEDKPLVSIDYVNDSRSSIIDGLSTMVVNGSQLKV
YAWYDNEWGYSSRMADLTCYISNLENTSNTF

Sequences:

>Translated_351_residues
MAKQGPMRIGINGFGRIGRLVFRALWGRPGIEICHVNDPSGEAATAAHLLEFDSVHGRWDQLVGGSENQLLVNQQTISYS
QGSTPGAVPWNDAGIDIVLECSGKFKSPETLSVYFDQHALKRVIVACPVKGKLAGKEVLNIVYGINHHLYDPKIDHLVTA
ASCTTNCLAPLVKVVHENFGISHGSITTLHDITNTQVPIDSFQKDLRRARSCLQSLIPTTTGSAKAIAMIFPDLEGKLNG
HAVRVPLLNASLTDAVFELKRSITVKDANEAFRHAAEHQLKGILGYEDKPLVSIDYVNDSRSSIIDGLSTMVVNGSQLKV
YAWYDNEWGYSSRMADLTCYISNLENTSNTF
>Mature_350_residues
AKQGPMRIGINGFGRIGRLVFRALWGRPGIEICHVNDPSGEAATAAHLLEFDSVHGRWDQLVGGSENQLLVNQQTISYSQ
GSTPGAVPWNDAGIDIVLECSGKFKSPETLSVYFDQHALKRVIVACPVKGKLAGKEVLNIVYGINHHLYDPKIDHLVTAA
SCTTNCLAPLVKVVHENFGISHGSITTLHDITNTQVPIDSFQKDLRRARSCLQSLIPTTTGSAKAIAMIFPDLEGKLNGH
AVRVPLLNASLTDAVFELKRSITVKDANEAFRHAAEHQLKGILGYEDKPLVSIDYVNDSRSSIIDGLSTMVVNGSQLKVY
AWYDNEWGYSSRMADLTCYISNLENTSNTF

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=342, Percent_Identity=38.8888888888889, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=38.6904761904762, Blast_Score=242, Evalue=3e-64,
Organism=Escherichia coli, GI1788079, Length=337, Percent_Identity=39.7626112759644, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789295, Length=342, Percent_Identity=35.672514619883, Blast_Score=225, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=39.1176470588235, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=39.1176470588235, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=38.8235294117647, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=38.5294117647059, Blast_Score=247, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=338, Percent_Identity=38.1656804733728, Blast_Score=256, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322409, Length=338, Percent_Identity=38.7573964497041, Blast_Score=256, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6322468, Length=337, Percent_Identity=37.9821958456973, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=39.039039039039, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=39.7014925373134, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=39.7014925373134, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=39.4029850746269, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=39.4029850746269, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 38403; Mature: 38272

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQGPMRIGINGFGRIGRLVFRALWGRPGIEICHVNDPSGEAATAAHLLEFDSVHGRWD
CCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHH
QLVGGSENQLLVNQQTISYSQGSTPGAVPWNDAGIDIVLECSGKFKSPETLSVYFDQHAL
HHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHH
KRVIVACPVKGKLAGKEVLNIVYGINHHLYDPKIDHLVTAASCTTNCLAPLVKVVHENFG
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHCC
ISHGSITTLHDITNTQVPIDSFQKDLRRARSCLQSLIPTTTGSAKAIAMIFPDLEGKLNG
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
HAVRVPLLNASLTDAVFELKRSITVKDANEAFRHAAEHQLKGILGYEDKPLVSIDYVNDS
CEEEEEEECCHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
RSSIIDGLSTMVVNGSQLKVYAWYDNEWGYSSRMADLTCYISNLENTSNTF
HHHHHHHHHHEEECCCEEEEEEEECCCCCCCCCHHEEEEEEECCCCCCCCC
>Mature Secondary Structure 
AKQGPMRIGINGFGRIGRLVFRALWGRPGIEICHVNDPSGEAATAAHLLEFDSVHGRWD
CCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHH
QLVGGSENQLLVNQQTISYSQGSTPGAVPWNDAGIDIVLECSGKFKSPETLSVYFDQHAL
HHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHH
KRVIVACPVKGKLAGKEVLNIVYGINHHLYDPKIDHLVTAASCTTNCLAPLVKVVHENFG
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHCC
ISHGSITTLHDITNTQVPIDSFQKDLRRARSCLQSLIPTTTGSAKAIAMIFPDLEGKLNG
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
HAVRVPLLNASLTDAVFELKRSITVKDANEAFRHAAEHQLKGILGYEDKPLVSIDYVNDS
CEEEEEEECCHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
RSSIIDGLSTMVVNGSQLKVYAWYDNEWGYSSRMADLTCYISNLENTSNTF
HHHHHHHHHHEEECCCEEEEEEEECCCCCCCCCHHEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]