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The map label for this gene is recD [H]

Identifier: 124022672

GI number: 124022672

Start: 874875

End: 876605

Strand: Direct

Name: recD [H]

Synonym: P9303_09631

Alternate gene names: 124022672

Gene position: 874875-876605 (Clockwise)

Preceding gene: 124022671

Following gene: 124022673

Centisome position: 32.61

GC content: 54.3

Gene sequence:

>1731_bases
ATGACTCGCAGCGATTCATCCACTTGGCCATCAGGTTTTCCCAGAGCACTGCATCAAACGTTGTTGAGGCGTCTCCCGCC
GAAGGCTTCATCAGTTCATCTCGAGGACTTGGTCAACGCCTTGATGGATGCATTAGCCCGCGGTGAGCTGCAGCTGAATC
TCACTGCGATGTCTCCCCCTCAAGAACTCAAAGCGATGGGATGGCCTGAGGCTCATTGTCAGGCCCTGCTGGCTAGTGGC
TGGCTGGAAGGCGCGGCTTCTCCGATGGTTTTAAACGGTAATCAATTGAGTTGGCGTCGTTGGCATGGTGATATGGACGC
TGTGATCAAGGAGTTGATCAACAGGTCAAATGTTGTTCAAGCGACTTCAATCTGCACCACACCATCCCATCATCCTGCTT
TGCTGGATGGGCTTAACCCTGAACAGCAGGCTGCCGTAGAAGCCATCGATAACCATGGCGTGGTGTTGTTGAGTGGCGGT
CCGGGTACGGGCAAAACCAGCACCATCGTGCAAATGTTGGCGCGGGCAGTCACGTTGAGACCAGGCCTGAGGATTGGTCT
TGCTGCTCCCACAGGCAAAGCGGCAAGACGCCTAGAGGAGGCTGTTCGCAAGGGGCTGGAGGCAATCCCTCCCACCCAGC
GGCAGGCATTGACCAGCCTGCCTTGTAGCACCCTCCACCGCTGGCTTCAGGCTAGGCCTGGTGGGTTTGGTAGGCATCAA
CAACACCCCCTAATGCTTGATCTCCTCGTTATTGATGAGATGTCGATGGTGGAGCTTTCCCTGATGCAGGCGTTATTAAG
CGCCCTGCCTATTGATAGTCAGCTTGTGATGATTGGTGACCCGGATCAGTTGCCTCCAGTTGGTAGTGGAGCGGTTTGGC
ATCAACTCCAACAGGCTGATATCCGCCAACAGTTCAATCATGGTGCCATTCACCTGCATCAGCTCTATCGCAACCGCGGT
TCACTAGCGACGTTGAGCAGAGTTCTGTGTGATCAGGGCCTTTCTGCTTTTTGGCAACAACTTTCTCTTCTGCCGAAATC
AGCGAACGTTGAGCAGCATCAATGCAACCTCAGCAGCATGCCAAGGTTTTTAGTTCAGCACTTGCAGGAGCACAGCAGAA
CACTGCAACGACTCACTGCCGAACTGATGCTCGAGCTGCCAGATGATGCTTATACGTCAACCATGCTCAACACCAATCTT
GCCGTTGCAGCTGAGTCTCTGCTGGATTCTCTCGAGCGGTTGATGGTGCTTTGTCCGAAACGTCGTGGTTTTTGGGGAGT
TGATGATGTGCATCGAGCATTGTTGGGTCAAAGCCTTGAGGCTGGAGTGATGCGCTGGCCGTTGGGAACGCCGGTGATGT
GTTGCGAGAACCAAGCGGAACTGGGGCTAGCAAACGGTGACGTTGGCTTGGTGGTTGGTCAAGGAGACAATCTGCGCATC
CTGTTTCGCGTGATCTCTGAGCAGGGAGGACTGACCACACGCTTCATCCACCCGGCCCGATTGAGCGTGGTGGAGCCAGC
TTTGGCTCTTACGGTTCATAAGTCTCAGGGGAGTGAGGCTGATCATGTCATTCTTCTCTGGCCGGAAATAAAAGCTGTGT
CGGCTACCAGTGCTGATGGTTTTGAGAGCGCTTCTAGCTTCGAGAGGAAACTTCTCTACACTGCTATCACGCGCGCGCGA
CAGCGAGTGGATCTCGTTACTGCAATGGCATCTGGTCGTAGTGACGGCTGA

Upstream 100 bases:

>100_bases
ACGGTCGCTCTCTTACTAAACCAGTGCCTGGCTTGATTGTTGAGCCCGCACCATTGGAGCGGGTTTTGCTTTTGGATCGC
TTGCTCAAGAACGGAGGACA

Downstream 100 bases:

>100_bases
GGCTGACGCCGCCATGCTGAACGCAACTGCTAGCAGAGGCATGAGCAAGGCCCCCCAGAGAGTTGAGCGTCCTTGGGGTT
GGTATGAAGATCTGCTCGAA

Product: exodeoxyribonuclease V 67 kD polypeptide

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSVHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASG
WLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQATSICTTPSHHPALLDGLNPEQQAAVEAIDNHGVVLLSGG
PGTGKTSTIVQMLARAVTLRPGLRIGLAAPTGKAARRLEEAVRKGLEAIPPTQRQALTSLPCSTLHRWLQARPGGFGRHQ
QHPLMLDLLVIDEMSMVELSLMQALLSALPIDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRG
SLATLSRVLCDQGLSAFWQQLSLLPKSANVEQHQCNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMLNTNL
AVAAESLLDSLERLMVLCPKRRGFWGVDDVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
LFRVISEQGGLTTRFIHPARLSVVEPALALTVHKSQGSEADHVILLWPEIKAVSATSADGFESASSFERKLLYTAITRAR
QRVDLVTAMASGRSDG

Sequences:

>Translated_576_residues
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSVHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASG
WLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQATSICTTPSHHPALLDGLNPEQQAAVEAIDNHGVVLLSGG
PGTGKTSTIVQMLARAVTLRPGLRIGLAAPTGKAARRLEEAVRKGLEAIPPTQRQALTSLPCSTLHRWLQARPGGFGRHQ
QHPLMLDLLVIDEMSMVELSLMQALLSALPIDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRG
SLATLSRVLCDQGLSAFWQQLSLLPKSANVEQHQCNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMLNTNL
AVAAESLLDSLERLMVLCPKRRGFWGVDDVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
LFRVISEQGGLTTRFIHPARLSVVEPALALTVHKSQGSEADHVILLWPEIKAVSATSADGFESASSFERKLLYTAITRAR
QRVDLVTAMASGRSDG
>Mature_575_residues
TRSDSSTWPSGFPRALHQTLLRRLPPKASSVHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASGW
LEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQATSICTTPSHHPALLDGLNPEQQAAVEAIDNHGVVLLSGGP
GTGKTSTIVQMLARAVTLRPGLRIGLAAPTGKAARRLEEAVRKGLEAIPPTQRQALTSLPCSTLHRWLQARPGGFGRHQQ
HPLMLDLLVIDEMSMVELSLMQALLSALPIDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRGS
LATLSRVLCDQGLSAFWQQLSLLPKSANVEQHQCNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMLNTNLA
VAAESLLDSLERLMVLCPKRRGFWGVDDVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRIL
FRVISEQGGLTTRFIHPARLSVVEPALALTVHKSQGSEADHVILLWPEIKAVSATSADGFESASSFERKLLYTAITRARQ
RVDLVTAMASGRSDG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=519, Percent_Identity=31.5992292870906, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 62856; Mature: 62725

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSVHLEDLVNALMDALARGELQLNLTAMSPP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEECCCH
QELKAMGWPEAHCQALLASGWLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQ
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHCCCCCEE
ATSICTTPSHHPALLDGLNPEQQAAVEAIDNHGVVLLSGGPGTGKTSTIVQMLARAVTLR
HHHEECCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PGLRIGLAAPTGKAARRLEEAVRKGLEAIPPTQRQALTSLPCSTLHRWLQARPGGFGRHQ
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
QHPLMLDLLVIDEMSMVELSLMQALLSALPIDSQLVMIGDPDQLPPVGSGAVWHQLQQAD
CCCCEEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
IRQQFNHGAIHLHQLYRNRGSLATLSRVLCDQGLSAFWQQLSLLPKSANVEQHQCNLSSM
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
PRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMLNTNLAVAAESLLDSLERLMVLCPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
RRGFWGVDDVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
CCCCCCHHHHHHHHHCCCHHCCCEECCCCCCEEEECCCCCCEECCCCEEEEEECCCCCEE
LFRVISEQGGLTTRFIHPARLSVVEPALALTVHKSQGSEADHVILLWPEIKAVSATSADG
HHHHHHCCCCCEEEEECCHHHHHHCCHHEEEEECCCCCCCCEEEEECCCCCEECCCCCCC
FESASSFERKLLYTAITRARQRVDLVTAMASGRSDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRSDSSTWPSGFPRALHQTLLRRLPPKASSVHLEDLVNALMDALARGELQLNLTAMSPP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEECCCH
QELKAMGWPEAHCQALLASGWLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQ
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHCCCCCEE
ATSICTTPSHHPALLDGLNPEQQAAVEAIDNHGVVLLSGGPGTGKTSTIVQMLARAVTLR
HHHEECCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PGLRIGLAAPTGKAARRLEEAVRKGLEAIPPTQRQALTSLPCSTLHRWLQARPGGFGRHQ
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
QHPLMLDLLVIDEMSMVELSLMQALLSALPIDSQLVMIGDPDQLPPVGSGAVWHQLQQAD
CCCCEEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
IRQQFNHGAIHLHQLYRNRGSLATLSRVLCDQGLSAFWQQLSLLPKSANVEQHQCNLSSM
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
PRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMLNTNLAVAAESLLDSLERLMVLCPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
RRGFWGVDDVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
CCCCCCHHHHHHHHHCCCHHCCCEECCCCCCEEEECCCCCCEECCCCEEEEEECCCCCEE
LFRVISEQGGLTTRFIHPARLSVVEPALALTVHKSQGSEADHVILLWPEIKAVSATSADG
HHHHHHCCCCCEEEEECCHHHHHHCCHHEEEEECCCCCCCCEEEEECCCCCEECCCCCCC
FESASSFERKLLYTAITRARQRVDLVTAMASGRSDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]