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The map label for this gene is accA

Identifier: 124022491

GI number: 124022491

Start: 717884

End: 718873

Strand: Direct

Name: accA

Synonym: P9303_07821

Alternate gene names: 124022491

Gene position: 717884-718873 (Clockwise)

Preceding gene: 124022490

Following gene: 124022492

Centisome position: 26.76

GC content: 53.84

Gene sequence:

>990_bases
ATGGCTCGTCGTTATCTGTTTGAGTTCGAAAAGCCATTGGTAGAACTAGAGCAGCAGATTGAGCAGATCCGAGAGCTTGC
ACGCGATTCCGAAGTCGATGTCAGTCAGCAGTTGCTCCAGTTAGAGACCTTGGCGGCTCGCAGACGGGAGGAAATTTTTC
AAGCTCTTACACCGGCCGAGAAAATTCAGGTGGCTCGCCATCCTCACCGGCCGAGTACCTTGGATTTTATCCAAATGTTT
TGCGACGACTGGGTTGAGTTGCATGGTGACCGTCGTGGTAGCGACGACCAGGCGTTGGTTGGTGGTGTCGGCCGTATTGG
TAAGCGCTCTGTGCTGCTGATCGGGCATCAAAAGGGCAGGGATACAAAAGAAAATGTGGCGAGAAACTTTGGGATGGCGA
CGCCTGGTGGTTACCGCAAGGCTCTTCGCCTGATGGATCATGCCGATCGTTTTCGTTTACCCATCCTCACTTTCATCGAT
ACGCCTGGTGCATATGCAGGCCTTCTTGCCGAGGAGCAGGGGCAAGGTGAAGCCATTGCAGTCAACTTGCGTGAAATGTT
CCGTTTGCGCGTGCCTGTGATTGCCACGGTGATTGGTGAAGGAGGGTCCGGTGGCGCTCTTGGAATTGGCGTAGCTGATC
GTTTGCTCATGTTTGAGCACAGCGTCTACACCGTGGCTAGTCCGGAAGCCTGTGCTTCGATTCTTTGGAGAGATGCCGCC
AAAGCTCCTGAGGCAGCTGCTGCTTTGAAGATTACTGGTCCAGATCTACTTAGCTTGGGAGTGGTGGATGAAGTGCTTCC
AGAACCAGCTGGAGGTAACAACTGGGCACCTCTTCAGGCGGGAGAGGTGCTCAGAGAGGCTATCGAGCGGCACCTCGATG
ATCTTCTTGGTTTAAAGGTTAATCAGCTTCGCGAATCGCGGTATCGGAAATTCCGGGCTATGGGTCGTGTTCTCGATCCA
AGCTCGTCGGAAACCGGCTTGCCTGCCTAG

Upstream 100 bases:

>100_bases
TCGGCATGGCGTCTTTGCGTCATGGCTTTTCAAGCCTCAATCTCAATCACCAACTTCAGGCTTCAGCAGCCTGAACCTTG
TTTCCGGATCTTCTCTTGTT

Downstream 100 bases:

>100_bases
GGTGATTGGGCTGCATTCGCTCCTTGCCTACTGCCCTGATTACTGGAGCATCTCGCGGTATTGGGGAAGCAGCTGCGCGG
TTGTTTGCAAATTCCGGTTG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAEKIQVARHPHRPSTLDFIQMF
CDDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGRDTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFID
TPGAYAGLLAEEQGQGEAIAVNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
KAPEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKVNQLRESRYRKFRAMGRVLDP
SSSETGLPA

Sequences:

>Translated_329_residues
MARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAEKIQVARHPHRPSTLDFIQMF
CDDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGRDTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFID
TPGAYAGLLAEEQGQGEAIAVNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
KAPEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKVNQLRESRYRKFRAMGRVLDP
SSSETGLPA
>Mature_328_residues
ARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAEKIQVARHPHRPSTLDFIQMFC
DDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGRDTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFIDT
PGAYAGLLAEEQGQGEAIAVNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAK
APEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKVNQLRESRYRKFRAMGRVLDPS
SSETGLPA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=48.8817891373802, Blast_Score=307, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PROM3 (A2C7S3)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016798.1
- ProteinModelPortal:   A2C7S3
- SMR:   A2C7S3
- STRING:   A2C7S3
- GeneID:   4778422
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_07821
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   GSPEPWG
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36302; Mature: 36171

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
KIQVARHPHRPSTLDFIQMFCDDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCC
DTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFIDTPGAYAGLLAEEQGQGEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCEEE
VNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
EEHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHC
KAPEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKV
CCCCHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
NQLRESRYRKFRAMGRVLDPSSSETGLPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
KIQVARHPHRPSTLDFIQMFCDDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCC
DTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFIDTPGAYAGLLAEEQGQGEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCEEE
VNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
EEHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHC
KAPEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKV
CCCCHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
NQLRESRYRKFRAMGRVLDPSSSETGLPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA