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The map label for this gene is cobO [H]

Identifier: 124022472

GI number: 124022472

Start: 702709

End: 703401

Strand: Reverse

Name: cobO [H]

Synonym: P9303_07631

Alternate gene names: 124022472

Gene position: 703401-702709 (Counterclockwise)

Preceding gene: 124022473

Following gene: 124022471

Centisome position: 26.22

GC content: 52.38

Gene sequence:

>693_bases
ATGACCAACCCGCCAGCTCCGCATTCGCCCTCTTCAACTGAACTCGATCAGAGCGCAGAAGTTCTTGGCATAGGCGGCCA
TTTAGCTCCCGAAACCGACCAACAGAGCTACCGCAAACGCATGCAGCGCCGACAAGACGTTCAGCGCCAACGTGTAGAAG
AACGAGACAAAGAGAAGGGCCTAATCCTTGTGTTCACAGGACATGGCAAAGGCAAAACCACAGCAGCGCTAGGGCTAGCC
TTACGCACCCTTGGCCATGGCGAGCGTGTTGCAGTCGTGCAATTCATTAAAGGAAGTTGGCAGCCAGGCGAAGCAAAAGC
GTTAAAAGTTTTTGGTGACGCATTGAGCTGGCATGCCTTTGGAGAGGGCTTCACCTGGACAACCCAAGACCGGGAAAGAG
ATCAACAATTGGTATCAAAAGCCTGGCAACAGGCTCTGATTTACCTCCACAGCAACAACCACAAACTTGTCGTGCTTGAT
GAGATCAATGTGGCAATGAAACTGGGTTACCTCAAGGTAGAAGAAGTACTAGGGGGGATCACGGAAAGGCCACCCCTAAC
CCACGTAGCACTCACTGGCCGGGGCGCACCAAAGGAGCTCATTGAACACGCAGATCTGGTCACAGAAATGACTTTGGTGC
ACCATCCCTTCAAGGAGCAAGGCGTCAAAGCACAAGCAGGCATTGAGTTTTGA

Upstream 100 bases:

>100_bases
GATCAAGAACTATTAGCAGGCCGAGCACTACAACGAATCACAGCCCGCCTTCCATAAGCAGCCCAACTCAAAGCATGCTC
AAGACCTTGCCAACATTTTG

Downstream 100 bases:

>100_bases
AGCAATCAATCATCTCCCCTCTAAATCTGCATCCAATAGCTGATCTGTAGCAACAAAAACCGACAGACCGTTCACCAGCA
AAGCTCTGCTCTATGCACAA

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTNPPAPHSPSSTELDQSAEVLGIGGHLAPETDQQSYRKRMQRRQDVQRQRVEERDKEKGLILVFTGHGKGKTTAALGLA
LRTLGHGERVAVVQFIKGSWQPGEAKALKVFGDALSWHAFGEGFTWTTQDRERDQQLVSKAWQQALIYLHSNNHKLVVLD
EINVAMKLGYLKVEEVLGGITERPPLTHVALTGRGAPKELIEHADLVTEMTLVHHPFKEQGVKAQAGIEF

Sequences:

>Translated_230_residues
MTNPPAPHSPSSTELDQSAEVLGIGGHLAPETDQQSYRKRMQRRQDVQRQRVEERDKEKGLILVFTGHGKGKTTAALGLA
LRTLGHGERVAVVQFIKGSWQPGEAKALKVFGDALSWHAFGEGFTWTTQDRERDQQLVSKAWQQALIYLHSNNHKLVVLD
EINVAMKLGYLKVEEVLGGITERPPLTHVALTGRGAPKELIEHADLVTEMTLVHHPFKEQGVKAQAGIEF
>Mature_229_residues
TNPPAPHSPSSTELDQSAEVLGIGGHLAPETDQQSYRKRMQRRQDVQRQRVEERDKEKGLILVFTGHGKGKTTAALGLAL
RTLGHGERVAVVQFIKGSWQPGEAKALKVFGDALSWHAFGEGFTWTTQDRERDQQLVSKAWQQALIYLHSNNHKLVVLDE
INVAMKLGYLKVEEVLGGITERPPLTHVALTGRGAPKELIEHADLVTEMTLVHHPFKEQGVKAQAGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=43.3673469387755, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 25547; Mature: 25416

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPPAPHSPSSTELDQSAEVLGIGGHLAPETDQQSYRKRMQRRQDVQRQRVEERDKEKG
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LILVFTGHGKGKTTAALGLALRTLGHGERVAVVQFIKGSWQPGEAKALKVFGDALSWHAF
EEEEEECCCCCCHHHHHHHHHHHCCCCCHHHEEHHHHCCCCCCCHHHHHHHHHHHHHHCC
GEGFTWTTQDRERDQQLVSKAWQQALIYLHSNNHKLVVLDEINVAMKLGYLKVEEVLGGI
CCCCEECCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCEEHHCCCEEHHHHHCCC
TERPPLTHVALTGRGAPKELIEHADLVTEMTLVHHPFKEQGVKAQAGIEF
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TNPPAPHSPSSTELDQSAEVLGIGGHLAPETDQQSYRKRMQRRQDVQRQRVEERDKEKG
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LILVFTGHGKGKTTAALGLALRTLGHGERVAVVQFIKGSWQPGEAKALKVFGDALSWHAF
EEEEEECCCCCCHHHHHHHHHHHCCCCCHHHEEHHHHCCCCCCCHHHHHHHHHHHHHHCC
GEGFTWTTQDRERDQQLVSKAWQQALIYLHSNNHKLVVLDEINVAMKLGYLKVEEVLGGI
CCCCEECCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCEEHHCCCEEHHHHHCCC
TERPPLTHVALTGRGAPKELIEHADLVTEMTLVHHPFKEQGVKAQAGIEF
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]