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The map label for this gene is argB

Identifier: 124022443

GI number: 124022443

Start: 678473

End: 679399

Strand: Reverse

Name: argB

Synonym: P9303_07341

Alternate gene names: 124022443

Gene position: 679399-678473 (Counterclockwise)

Preceding gene: 124022444

Following gene: 124022442

Centisome position: 25.33

GC content: 57.17

Gene sequence:

>927_bases
ATGGAGTCAGCTAAATCTGCTGCAGCGCTGGTTGAGCCCTGCCAAACCAACTCCGCGAGAAGGCTTACAGAGGATGACTC
CCTCAGGGTTTCGGTGCTTAGCGAAGCCCTCCCTTACATCCAACGTTTTAGCGGACGGCGCATTGTCATCAAATACGGCG
GTGCCGCCATGGCCCACGCCAATTTGCAGGAAGCGGTTTTTCGCGACCTTGCCCTACTCGTCAGTGTGGGAGTAGAGCCC
GTTGTGGTTCATGGCGGCGGACCAGAAATCAACCAATGGCTGGAAAGGCTTGAGATTCCAGCAAAGTTCCGCGACGGACT
TCGCGTTACCGATGCAGACACCATGGACGTGGTGGAAATGGTCTTAGTTGGACGCGTTAACAAGCAAATCGTTAATGGCC
TCAACCAACTGGGGGCCAAGGCTGTTGGCCTTAGTGGCAGTGACGGGAGTCTGGTTGAAGCCCGACCCTGGGGCGACGGC
AGCCATGGCCTCGTCGGAGATGTAGCCCGAGTCAACACCGATGTACTGGAACCAATTCTCGCAAAGGGTTATGTACCAGT
GATCTCAAGCGTGGCCGCCACTGTTGAGGGCTGCTCCCACAACATCAATGCAGACACGGTCGCCGGTGAGATCGCCGCTG
CTCTTGAAGCAGAGAAGCTAATCCTGCTGACCGACACGCCAGGCATCTTGCTAGATCGGGATGATCCAAGTTCCCTTGTT
CATCAGTTGCGTCTATCTGAAGCACGCCAGCTCATCGCTGAAGGGGTGGTGGCTGGCGGCATGACCCCAAAAACCGAATG
CTGCATCAGAGCTCTAGCTCAAGGGGTCGGCGCTGCCCATATCATCGATGGACGTGTTCCACACGCCCTGCTTCTCGAGG
TGTTCACCGACGCCGGCATCGGCACCATGGTGGTCGGTCGCAGCTGA

Upstream 100 bases:

>100_bases
TTTGCCAAAGGCCTTCACGCCGAACTGAAATCTCCAAGCGCGGGGGTCCTGGATCTCATCCTGCTGCCAGTCAACAAGGA
TGATGAACTGGCAGGTCAAG

Downstream 100 bases:

>100_bases
GCGATGCACGCGAATCTGGCCGAGGCTGAAGCCGCCCTCGCCCGGGGAGACTATGGCCAAAGCCTTGCTCTATTAGAGCC
TTTAGCAGCAAGCCATCCAC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MESAKSAAALVEPCQTNSARRLTEDDSLRVSVLSEALPYIQRFSGRRIVIKYGGAAMAHANLQEAVFRDLALLVSVGVEP
VVVHGGGPEINQWLERLEIPAKFRDGLRVTDADTMDVVEMVLVGRVNKQIVNGLNQLGAKAVGLSGSDGSLVEARPWGDG
SHGLVGDVARVNTDVLEPILAKGYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSSLV
HQLRLSEARQLIAEGVVAGGMTPKTECCIRALAQGVGAAHIIDGRVPHALLLEVFTDAGIGTMVVGRS

Sequences:

>Translated_308_residues
MESAKSAAALVEPCQTNSARRLTEDDSLRVSVLSEALPYIQRFSGRRIVIKYGGAAMAHANLQEAVFRDLALLVSVGVEP
VVVHGGGPEINQWLERLEIPAKFRDGLRVTDADTMDVVEMVLVGRVNKQIVNGLNQLGAKAVGLSGSDGSLVEARPWGDG
SHGLVGDVARVNTDVLEPILAKGYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSSLV
HQLRLSEARQLIAEGVVAGGMTPKTECCIRALAQGVGAAHIIDGRVPHALLLEVFTDAGIGTMVVGRS
>Mature_308_residues
MESAKSAAALVEPCQTNSARRLTEDDSLRVSVLSEALPYIQRFSGRRIVIKYGGAAMAHANLQEAVFRDLALLVSVGVEP
VVVHGGGPEINQWLERLEIPAKFRDGLRVTDADTMDVVEMVLVGRVNKQIVNGLNQLGAKAVGLSGSDGSLVEARPWGDG
SHGLVGDVARVNTDVLEPILAKGYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSSLV
HQLRLSEARQLIAEGVVAGGMTPKTECCIRALAQGVGAAHIIDGRVPHALLLEVFTDAGIGTMVVGRS

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=288, Percent_Identity=28.125, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693208, Length=225, Percent_Identity=34.2222222222222, Blast_Score=98, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=289, Percent_Identity=30.4498269896194, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PROM3 (A2C7M5)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016750.1
- ProteinModelPortal:   A2C7M5
- SMR:   A2C7M5
- STRING:   A2C7M5
- GeneID:   4777303
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_07341
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32357; Mature: 32357

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: BINDING 108-108 BINDING 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAKSAAALVEPCQTNSARRLTEDDSLRVSVLSEALPYIQRFSGRRIVIKYGGAAMAHA
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
NLQEAVFRDLALLVSVGVEPVVVHGGGPEINQWLERLEIPAKFRDGLRVTDADTMDVVEM
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCEECCCHHHHHHHH
VLVGRVNKQIVNGLNQLGAKAVGLSGSDGSLVEARPWGDGSHGLVGDVARVNTDVLEPIL
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
AKGYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSSLV
HCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHH
HQLRLSEARQLIAEGVVAGGMTPKTECCIRALAQGVGAAHIIDGRVPHALLLEVFTDAGI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC
GTMVVGRS
CEEEECCC
>Mature Secondary Structure
MESAKSAAALVEPCQTNSARRLTEDDSLRVSVLSEALPYIQRFSGRRIVIKYGGAAMAHA
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
NLQEAVFRDLALLVSVGVEPVVVHGGGPEINQWLERLEIPAKFRDGLRVTDADTMDVVEM
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCEECCCHHHHHHHH
VLVGRVNKQIVNGLNQLGAKAVGLSGSDGSLVEARPWGDGSHGLVGDVARVNTDVLEPIL
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
AKGYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSSLV
HCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHH
HQLRLSEARQLIAEGVVAGGMTPKTECCIRALAQGVGAAHIIDGRVPHALLLEVFTDAGI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC
GTMVVGRS
CEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA