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The map label for this gene is thiP [H]

Identifier: 124022417

GI number: 124022417

Start: 658660

End: 660261

Strand: Reverse

Name: thiP [H]

Synonym: P9303_07081

Alternate gene names: 124022417

Gene position: 660261-658660 (Counterclockwise)

Preceding gene: 124022419

Following gene: 124022416

Centisome position: 24.61

GC content: 55.37

Gene sequence:

>1602_bases
ATGACCCAAGACGCCGTCCCGTCAAGCTACGGCTCGAACCGCCTGCGCAAACGCCATTGGCAACCAGACCGCCTGCTTCT
CAACAGCATGGCAATTCTGCTTGCTGTACTTGCTCTCTGGCCTCTGATTGGTCTGATCCGTGAAGCACTGCAGGGATTCA
TCAATGGATCGGCCAGCCTGGGAGTCGATGGCCCACAACAGATTCAAGGGACCTTGACTCTGCTGATCGGGACATCCTTA
TTGGGTGGCCTACTGGGAACTGCAAACGGCTGGTTATTAGCAAACTGCCGCTTCCCAGGACGTCGAGCCCTACGAGTGGC
TCAGCTATTGCCCCTCGCCACACCCGCCTACCTACTCTCGGCCATCCTGATCGATCTTGGCAGTCGCAATGCCATACGAA
TTCATGGCATGGGCTGGGGGATTTTGATCATGGCGCTGACAACCTATCCCTACGTTTTTCTCCTCAGCACTGAAAGCTTT
TCAATCTGCGGACGCCGCCAACTGGAAGCCTGCCGCAGTCTTGGGGTTGGACCGTGGAACAGTTTTCGACGCATTGCTCT
GCCCATGGCTTTGCCAGCGATTGGTGCCGGGATTGCCCTGATGGGCATGGAAGTCGTCAATGAACTCGGGGCCGTAGCAC
TACTCGCCATCCCAAGCCTGTCAGCTGGCATCGTTGAGACCTGGCAAATGGAAGGCAATCCTGCCGGTGCCATTGGACTA
GCAATGATCGCGCTGATCATCGTGATGTCACTGGTGGGGTATGAACGCAGACTGAGACGACGAAGCCGCCGCTGGACAGA
GGGTGTCGCTGGTGGCGATTCTCCAGCCTGGCAGCTGCACGGTGTACGAGCCCTGTGCGCTCAGTGCCTAGCCCTCATTC
CTCCCACGATCACTTTGGGTGTGCCCCTGCTGTGGGCCATCCTCAATCTCGATCAACTCGAACAAGGGATAGATCCTGAT
CTAATCCCACTGACAGAACGCAGTCTTGGACTTGGGCTGGCAGCAGCAAGCCTGGCCGTGGTAGCAGGTCTGATCCTTGC
AATCGCCAAGCGTTGGTCATCAACACGCTGGATGGGCAACCTCTCATTTATGGCAGGTATTGGTTATGCCATTCCAGGAG
CTGTGATGGCCATTGCGCTGATGCCATTCAACGGTGCTCCATGGAACCTCGCATGGATTCTGCTGCTGCTGTGGGGCTAT
AGCGATCGCTTCTTGGCAGTTGCAAAAGGAGGACTCGACGCTGCCTTCGAGCGCCTTTCCCCAAGCCTGGATGAAGCCGC
TACTGGACTTGGCTGTCAATGGCAGGAGGTGCTTCGACGCGTTCATCTGCCTTTACTGAAAGGTCCACTAGCGGTAGGAG
CACTTTTGGTTTTTGTCGACACGGTTAAAGAACTACCTCTCACATTTGTCCTGAGACCATTTGATTTCGACACCCTTTCT
GTACGGCTCTACCAATACGCCGCAGATGAACGCATGGCGGAATCCATCTTGCCAGCACTGATTATCATCGCTCTGGGATT
AATCGCTTCGCTGGCATTGGTCCCAGGGCTCGATCAAGGGGAACGAAAAAAGCCTCCTTTAAGTAAAGAACCACTCACTT
AG

Upstream 100 bases:

>100_bases
TCTTCACCGCTGCAGAACTCTGCCAATGCCACCCAACTTCGCTTGCTCAACATCAAAACCTTCTCCCTGATGGCCTCTAA
CGGTTGAGATTGATCGCCTG

Downstream 100 bases:

>100_bases
TTTTCAATACTTCAAATGATCGTCAACAAGAGTTTTGGGTCGGTTTCAGGAAGGCAGACCCCATTCAAAACCACAGACTC
ATAACAAGCGAGAATTGCGA

Product: iron ABC transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: Iron(III)-transport system permease protein fbpB 2 [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MTQDAVPSSYGSNRLRKRHWQPDRLLLNSMAILLAVLALWPLIGLIREALQGFINGSASLGVDGPQQIQGTLTLLIGTSL
LGGLLGTANGWLLANCRFPGRRALRVAQLLPLATPAYLLSAILIDLGSRNAIRIHGMGWGILIMALTTYPYVFLLSTESF
SICGRRQLEACRSLGVGPWNSFRRIALPMALPAIGAGIALMGMEVVNELGAVALLAIPSLSAGIVETWQMEGNPAGAIGL
AMIALIIVMSLVGYERRLRRRSRRWTEGVAGGDSPAWQLHGVRALCAQCLALIPPTITLGVPLLWAILNLDQLEQGIDPD
LIPLTERSLGLGLAAASLAVVAGLILAIAKRWSSTRWMGNLSFMAGIGYAIPGAVMAIALMPFNGAPWNLAWILLLLWGY
SDRFLAVAKGGLDAAFERLSPSLDEAATGLGCQWQEVLRRVHLPLLKGPLAVGALLVFVDTVKELPLTFVLRPFDFDTLS
VRLYQYAADERMAESILPALIIIALGLIASLALVPGLDQGERKKPPLSKEPLT

Sequences:

>Translated_533_residues
MTQDAVPSSYGSNRLRKRHWQPDRLLLNSMAILLAVLALWPLIGLIREALQGFINGSASLGVDGPQQIQGTLTLLIGTSL
LGGLLGTANGWLLANCRFPGRRALRVAQLLPLATPAYLLSAILIDLGSRNAIRIHGMGWGILIMALTTYPYVFLLSTESF
SICGRRQLEACRSLGVGPWNSFRRIALPMALPAIGAGIALMGMEVVNELGAVALLAIPSLSAGIVETWQMEGNPAGAIGL
AMIALIIVMSLVGYERRLRRRSRRWTEGVAGGDSPAWQLHGVRALCAQCLALIPPTITLGVPLLWAILNLDQLEQGIDPD
LIPLTERSLGLGLAAASLAVVAGLILAIAKRWSSTRWMGNLSFMAGIGYAIPGAVMAIALMPFNGAPWNLAWILLLLWGY
SDRFLAVAKGGLDAAFERLSPSLDEAATGLGCQWQEVLRRVHLPLLKGPLAVGALLVFVDTVKELPLTFVLRPFDFDTLS
VRLYQYAADERMAESILPALIIIALGLIASLALVPGLDQGERKKPPLSKEPLT
>Mature_532_residues
TQDAVPSSYGSNRLRKRHWQPDRLLLNSMAILLAVLALWPLIGLIREALQGFINGSASLGVDGPQQIQGTLTLLIGTSLL
GGLLGTANGWLLANCRFPGRRALRVAQLLPLATPAYLLSAILIDLGSRNAIRIHGMGWGILIMALTTYPYVFLLSTESFS
ICGRRQLEACRSLGVGPWNSFRRIALPMALPAIGAGIALMGMEVVNELGAVALLAIPSLSAGIVETWQMEGNPAGAIGLA
MIALIIVMSLVGYERRLRRRSRRWTEGVAGGDSPAWQLHGVRALCAQCLALIPPTITLGVPLLWAILNLDQLEQGIDPDL
IPLTERSLGLGLAAASLAVVAGLILAIAKRWSSTRWMGNLSFMAGIGYAIPGAVMAIALMPFNGAPWNLAWILLLLWGYS
DRFLAVAKGGLDAAFERLSPSLDEAATGLGCQWQEVLRRVHLPLLKGPLAVGALLVFVDTVKELPLTFVLRPFDFDTLSV
RLYQYAADERMAESILPALIIIALGLIASLALVPGLDQGERKKPPLSKEPLT

Specific function: Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=169, Percent_Identity=30.1775147928994, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57232; Mature: 57101

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDAVPSSYGSNRLRKRHWQPDRLLLNSMAILLAVLALWPLIGLIREALQGFINGSASL
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVDGPQQIQGTLTLLIGTSLLGGLLGTANGWLLANCRFPGRRALRVAQLLPLATPAYLLS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHH
AILIDLGSRNAIRIHGMGWGILIMALTTYPYVFLLSTESFSICGRRQLEACRSLGVGPWN
HHHHHCCCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCH
SFRRIALPMALPAIGAGIALMGMEVVNELGAVALLAIPSLSAGIVETWQMEGNPAGAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHHH
AMIALIIVMSLVGYERRLRRRSRRWTEGVAGGDSPAWQLHGVRALCAQCLALIPPTITLG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
VPLLWAILNLDQLEQGIDPDLIPLTERSLGLGLAAASLAVVAGLILAIAKRWSSTRWMGN
HHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSFMAGIGYAIPGAVMAIALMPFNGAPWNLAWILLLLWGYSDRFLAVAKGGLDAAFERLS
HHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHC
PSLDEAATGLGCQWQEVLRRVHLPLLKGPLAVGALLVFVDTVKELPLTFVLRPFDFDTLS
CCHHHHHCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHH
VRLYQYAADERMAESILPALIIIALGLIASLALVPGLDQGERKKPPLSKEPLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQDAVPSSYGSNRLRKRHWQPDRLLLNSMAILLAVLALWPLIGLIREALQGFINGSASL
CCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVDGPQQIQGTLTLLIGTSLLGGLLGTANGWLLANCRFPGRRALRVAQLLPLATPAYLLS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHH
AILIDLGSRNAIRIHGMGWGILIMALTTYPYVFLLSTESFSICGRRQLEACRSLGVGPWN
HHHHHCCCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCH
SFRRIALPMALPAIGAGIALMGMEVVNELGAVALLAIPSLSAGIVETWQMEGNPAGAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHHH
AMIALIIVMSLVGYERRLRRRSRRWTEGVAGGDSPAWQLHGVRALCAQCLALIPPTITLG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
VPLLWAILNLDQLEQGIDPDLIPLTERSLGLGLAAASLAVVAGLILAIAKRWSSTRWMGN
HHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSFMAGIGYAIPGAVMAIALMPFNGAPWNLAWILLLLWGYSDRFLAVAKGGLDAAFERLS
HHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHC
PSLDEAATGLGCQWQEVLRRVHLPLLKGPLAVGALLVFVDTVKELPLTFVLRPFDFDTLS
CCHHHHHCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHH
VRLYQYAADERMAESILPALIIIALGLIASLALVPGLDQGERKKPPLSKEPLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 7927717 [H]