Click here to switch to the map view.

The map label for this gene is rnpA

Identifier: 124022321

GI number: 124022321

Start: 577193

End: 577579

Strand: Reverse

Name: rnpA

Synonym: P9303_06111

Alternate gene names: 124022321

Gene position: 577579-577193 (Counterclockwise)

Preceding gene: 124022322

Following gene: 124022320

Centisome position: 21.53

GC content: 53.49

Gene sequence:

>387_bases
ATGGTGCTGCCAGCATCAATGCGATTAAGGGGAAGTCGATGTTTTGAGCGCCTTCAGAAGTGGGGCTATCGCTTTTATGG
AACTTCAATGGTGCTCCGTGTCATCGAAGCAGATCCCCAACTGCTCAAAGCACCCCATCGGCACCACAACTCCACGGCAT
GCCGTTGTGCCGTTGTGATCAGCAGCAAAGTGAGCAAACGGGCCGTCATTCGCAACCGTCTGCGTCGACGTCTGCACAAT
CACCTAAGGAGCAGGCTTGAGGTTGCACCCGAGCATTGCAATCACTGGGTGCTGATCAGCCTCAAGCCAGTCGCATCCGC
AATAGAGGCGTCTCCATTGCTAGAAGAATGCGACAGATTGCTCCATCAAGCAGGTTTGTTGTCATGA

Upstream 100 bases:

>100_bases
CAGTCGCCGAAAACGTGGCCGCACTCGTCTCGCTGTCTAATCGATAACACTGCGGGGCAATCACTCAAATCACGCCACTT
CCTCAGGAAGCCAACCTCCA

Downstream 100 bases:

>100_bases
TCACAACCTCAGAAGAGGTCTTCTATGAGGGAGGCCCCGCTCAAAGCGATCTCATCATCAACCTATTGATGGGGCTAACG
CTGATTGGCCTTCCTTTCAC

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVISSKVSKRAVIRNRLRRRLHN
HLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRLLHQAGLLS

Sequences:

>Translated_128_residues
MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVISSKVSKRAVIRNRLRRRLHN
HLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRLLHQAGLLS
>Mature_128_residues
MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVISSKVSKRAVIRNRLRRRLHN
HLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRLLHQAGLLS

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_PROM3 (A2C7A3)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016628.1
- ProteinModelPortal:   A2C7A3
- STRING:   A2C7A3
- GeneID:   4777330
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_06111
- HOGENOM:   HBG728160
- OMA:   MRLKGHR
- ProtClustDB:   CLSK919642
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14723; Mature: 14723

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVI
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHH
SSKVSKRAVIRNRLRRRLHNHLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEEHHHHHHHHCCHHHHHHHHH
LHQAGLLS
HHHHCCCC
>Mature Secondary Structure
MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVI
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHH
SSKVSKRAVIRNRLRRRLHNHLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEEHHHHHHHHCCHHHHHHHHH
LHQAGLLS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA