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The map label for this gene is pyrR [H]

Identifier: 124022219

GI number: 124022219

Start: 501287

End: 501838

Strand: Direct

Name: pyrR [H]

Synonym: P9303_05091

Alternate gene names: 124022219

Gene position: 501287-501838 (Clockwise)

Preceding gene: 124022214

Following gene: 124022221

Centisome position: 18.69

GC content: 55.07

Gene sequence:

>552_bases
ATGATCGACAAAGGTAGTGATGAACGGGTTGAGATCCTCTCTGAGCAGGAGCTCGGTCGCACCCTTTCGCGCCTTGCTTC
TCAAGTACTTGAGTCTGTTTCTGATAGTCGGGAGCTTTTGTTCCTGGGAATTCCTACGCGAGGGGTTCATCTGTCTCGTG
TCTTGGCCAAAGAGTTGGAACCCATTGCGGGCCATAGCATTGATCAGGGAAGTTTGGACCCCACCTTTCATCGTGATGAT
CTGGGTCGAGTCGGTACTCGGATGGTGCAACCCACCGATCTCCCCAACAGCGTTGAGGGGCGAGAGGTTGTGTTGGTGGA
TGATGTGATTTTTACCGGTCGCACAGTGCGCGCTGCCCTTGAAGCTCTTCAGGCCTGGGGCAGGCCTCAGCGGGTGATGT
TGTTGGTGATGGTGGATCGCGGTCACCGGGAAGTGCCGATTCAACCAGATTTCTGTGGTCGCAAAGTGCCGACTCGTCGC
ACGGAAAGCATCGAATTGCGCCTCTCTGATGTGGATGGAGAAGAGGGGGTTTACTTGCGCCAGTTGCCTTGA

Upstream 100 bases:

>100_bases
TTGGTCTGCATTTGTGCTGACTTCCGTCAGCTTTTACGCATTGATTGTTGTTGGAGGCAGGAGAAGATCGGCATAAACTC
ACGTCTTAATCGTCACGACC

Downstream 100 bases:

>100_bases
TGAGGACTACACGCTGAGCTGGTGAACTTTGTGTTCATGCATCGGCGCTGTTCGTCTTGATGACAGAAGTCAGTTCAGCC
CATGGTCGTCTTGCCTTTGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MIDKGSDERVEILSEQELGRTLSRLASQVLESVSDSRELLFLGIPTRGVHLSRVLAKELEPIAGHSIDQGSLDPTFHRDD
LGRVGTRMVQPTDLPNSVEGREVVLVDDVIFTGRTVRAALEALQAWGRPQRVMLLVMVDRGHREVPIQPDFCGRKVPTRR
TESIELRLSDVDGEEGVYLRQLP

Sequences:

>Translated_183_residues
MIDKGSDERVEILSEQELGRTLSRLASQVLESVSDSRELLFLGIPTRGVHLSRVLAKELEPIAGHSIDQGSLDPTFHRDD
LGRVGTRMVQPTDLPNSVEGREVVLVDDVIFTGRTVRAALEALQAWGRPQRVMLLVMVDRGHREVPIQPDFCGRKVPTRR
TESIELRLSDVDGEEGVYLRQLP
>Mature_183_residues
MIDKGSDERVEILSEQELGRTLSRLASQVLESVSDSRELLFLGIPTRGVHLSRVLAKELEPIAGHSIDQGSLDPTFHRDD
LGRVGTRMVQPTDLPNSVEGREVVLVDDVIFTGRTVRAALEALQAWGRPQRVMLLVMVDRGHREVPIQPDFCGRKVPTRR
TESIELRLSDVDGEEGVYLRQLP

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20471; Mature: 20471

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKGSDERVEILSEQELGRTLSRLASQVLESVSDSRELLFLGIPTRGVHLSRVLAKELE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCC
PIAGHSIDQGSLDPTFHRDDLGRVGTRMVQPTDLPNSVEGREVVLVDDVIFTGRTVRAAL
HHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEECCCHHHHHHH
EALQAWGRPQRVMLLVMVDRGHREVPIQPDFCGRKVPTRRTESIELRLSDVDGEEGVYLR
HHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEE
QLP
ECC
>Mature Secondary Structure
MIDKGSDERVEILSEQELGRTLSRLASQVLESVSDSRELLFLGIPTRGVHLSRVLAKELE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCC
PIAGHSIDQGSLDPTFHRDDLGRVGTRMVQPTDLPNSVEGREVVLVDDVIFTGRTVRAAL
HHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEECCCHHHHHHH
EALQAWGRPQRVMLLVMVDRGHREVPIQPDFCGRKVPTRRTESIELRLSDVDGEEGVYLR
HHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEE
QLP
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA