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The map label for this gene is atpB [H]

Identifier: 124022188

GI number: 124022188

Start: 476019

End: 476744

Strand: Direct

Name: atpB [H]

Synonym: P9303_04781

Alternate gene names: 124022188

Gene position: 476019-476744 (Clockwise)

Preceding gene: 124022187

Following gene: 124022189

Centisome position: 17.74

GC content: 50.83

Gene sequence:

>726_bases
ATGGGTTTCTTGCCAATTGCTCTTCCCTTTGCCGAACTGGAAGTGGGTCAACACCTTTACTGGCAGATTGGCAATCTTCA
GCTCCATGGCCAGGTGTTCTTGACATCCTGGATTGTGATTGGCGCCATTCTTGCCCTTGTTGTTGTGGGCACACGCAAGA
TGGAGCGTGATCCACACGGTGTTCAAAATCTTCTCGAGTTCCTCTGGGATTACATCCGTGATTTAGCTCGCACCCAGATT
GGCGAGAAGGCTTATCGCGATTGGATGCCATTCATTGGCACCCTGTTCTTGTTCATCTTTGTAAGCAATTGGGGCGGGTC
TTTGGTCCCATGGAAATTAATCCACCTCCCCAGTGGGGAGTTGGGTGCTCCTACGGCTGATATCAATACCACCGTGGCAC
TTGCTCTACTTGTGTCGCTCTCTTACTTCTATGCCGGTTTGAGTCGGAAGGGATTGCGGTACTTCGAGTACTACGTCCAT
CCCACCCCGATCATGATCCCCTTCAAGATCGTGGAGGATTTCACCAAGCCTTTATCACTCTCCTTTCGTCTGTTTGGAAA
CATCCTTGCTGATGAATTGGTTGTTGCGGTTTTGGTTTTCCTTGTTCCCCTCTTCCTGCCAGTCCCGGTCATGTTCCTTG
GCCTGTTCACCAGTGCCATTCAGGCTCTAATCTTCGCCACCCTCGCCGCCTATTACATCGGTGAAGCGGTTGAAGAGCAC
CATTGA

Upstream 100 bases:

>100_bases
GCTTGAGTCATGAACTTGAACCAAACCTGGATCAACTGAATTGCCGGTTTGCCGGCTTCTCCTCAAACCGTCGTTTTCTC
GACACCGAATTTCCAGCCTG

Downstream 100 bases:

>100_bases
TCAAACTCTGATCTAGCAAGGCCTAACCCCTCGGTCTGGCAAACTCCATGCGCGCAGGTCCGGCTTGTTCGGGCCCATCT
CACAATCTCCGAGATGTCCC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHGVQNLLEFLWDYIRDLARTQI
GEKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGELGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVH
PTPIMIPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H

Sequences:

>Translated_241_residues
MGFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHGVQNLLEFLWDYIRDLARTQI
GEKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGELGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVH
PTPIMIPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H
>Mature_240_residues
GFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHGVQNLLEFLWDYIRDLARTQIG
EKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGELGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVHP
TPIMIPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 27159; Mature: 27028

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHG
CCCCCHHCHHHHHHHCCHHHEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VQNLLEFLWDYIRDLARTQIGEKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
LGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVHPTPIMIPFKIVEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEHHHHHHHHHHHHHH
SFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
H
C
>Mature Secondary Structure 
GFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHG
CCCCHHCHHHHHHHCCHHHEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VQNLLEFLWDYIRDLARTQIGEKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
LGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVHPTPIMIPFKIVEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEHHHHHHHHHHHHHH
SFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA