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The map label for this gene is rpiA

Identifier: 124022142

GI number: 124022142

Start: 433325

End: 434041

Strand: Direct

Name: rpiA

Synonym: P9303_04321

Alternate gene names: 124022142

Gene position: 433325-434041 (Clockwise)

Preceding gene: 124022141

Following gene: 124022144

Centisome position: 16.15

GC content: 54.39

Gene sequence:

>717_bases
ATGGCGGACCTTCAAACTCAGATGAAGCAAGCGGTGGCGGCAGCCGCTGTGGAGCAGATCAAAGATGGCATGGTTCTTGG
TTTGGGCTCAGGCTCGACGGCAGCTCTGATGATCCAGGCTCTTGGTGCCAAGCTGGCCAGTGGTGAGCTTCGGGAGATTG
TTGGCGTTACCACCTCTTTCCAAGGCGAAGTGATGGCTGCGGAGTTGGGGATTCCCTTGCGCAACCTCACGGCCGTGGAT
CGCATCGACTTGGCGATCGATGGAGCTGATGAAGTTGATCCCTCTTTTCAGTTAATTAAAGGTGGCGGGGCCTGCCATGT
GCAGGAGAAGCTTGTCGCCAGTAGAGCGGATCGCTTTGTGGTTGTTGTTGATTCCACAAAGATTGTTGATCGGCTCAACC
TTGGTTTTTTACTTCCGGTTGAGGTCTTGCCTGGTGCTTGGCGACAGGTGCAGGGTCGCTTGGCTGAGTTGGGCGGTATT
GCTGATTTGCGTATGGCTCAGTGCAAGGCTGGTCCTGTGGTCACCGATCAGGGCAATCTCGTTTTGGATGTGAGCATGGC
CGGAGGGATTGGTGACCCTGAGGATTTGGAGTGTCGAATTAACAATCTTCCGGGTGTCTTGGAGAACGGTTTGTTCGTCA
ATCTCACCGATGAAGTTTTGGTTGGCCAGATTAGTGATGGTGTTGCGGGAGTGCGTCGTCTACAGCGCCGTGAGTAG

Upstream 100 bases:

>100_bases
CAATGGTCAAGAGATGAGCCTTTCGGTTAATCCAGCCGCATTACCTGGCCTTAGTTGAAACCCTTGCCCTTGCTACCGTC
GCGCCGATGATTCAGAAACG

Downstream 100 bases:

>100_bases
AGGGGTTATTCGAAGCGGATACGCACGGATTCAGCATGGCTGTGCAAGCCTTCGCTGCTGGCCAATTCCCTTACGGCGTT
AGCAGTGGCCTCAAGGGCTG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MADLQTQMKQAVAAAAVEQIKDGMVLGLGSGSTAALMIQALGAKLASGELREIVGVTTSFQGEVMAAELGIPLRNLTAVD
RIDLAIDGADEVDPSFQLIKGGGACHVQEKLVASRADRFVVVVDSTKIVDRLNLGFLLPVEVLPGAWRQVQGRLAELGGI
ADLRMAQCKAGPVVTDQGNLVLDVSMAGGIGDPEDLECRINNLPGVLENGLFVNLTDEVLVGQISDGVAGVRRLQRRE

Sequences:

>Translated_238_residues
MADLQTQMKQAVAAAAVEQIKDGMVLGLGSGSTAALMIQALGAKLASGELREIVGVTTSFQGEVMAAELGIPLRNLTAVD
RIDLAIDGADEVDPSFQLIKGGGACHVQEKLVASRADRFVVVVDSTKIVDRLNLGFLLPVEVLPGAWRQVQGRLAELGGI
ADLRMAQCKAGPVVTDQGNLVLDVSMAGGIGDPEDLECRINNLPGVLENGLFVNLTDEVLVGQISDGVAGVRRLQRRE
>Mature_237_residues
ADLQTQMKQAVAAAAVEQIKDGMVLGLGSGSTAALMIQALGAKLASGELREIVGVTTSFQGEVMAAELGIPLRNLTAVDR
IDLAIDGADEVDPSFQLIKGGGACHVQEKLVASRADRFVVVVDSTKIVDRLNLGFLLPVEVLPGAWRQVQGRLAELGGIA
DLRMAQCKAGPVVTDQGNLVLDVSMAGGIGDPEDLECRINNLPGVLENGLFVNLTDEVLVGQISDGVAGVRRLQRRE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=237, Percent_Identity=39.662447257384, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI1789280, Length=229, Percent_Identity=39.3013100436681, Blast_Score=134, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17551758, Length=231, Percent_Identity=36.3636363636364, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324669, Length=232, Percent_Identity=37.5, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=42.512077294686, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PROM3 (A2C6S4)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016449.1
- ProteinModelPortal:   A2C6S4
- SMR:   A2C6S4
- STRING:   A2C6S4
- GeneID:   4776210
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_04321
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24992; Mature: 24861

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLQTQMKQAVAAAAVEQIKDGMVLGLGSGSTAALMIQALGAKLASGELREIVGVTTSF
CCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCHHCCCHHHHHHHCCCCC
QGEVMAAELGIPLRNLTAVDRIDLAIDGADEVDPSFQLIKGGGACHVQEKLVASRADRFV
CCCEEEEECCCCHHHCCHHHEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEE
VVVDSTKIVDRLNLGFLLPVEVLPGAWRQVQGRLAELGGIADLRMAQCKAGPVVTDQGNL
EEECCHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCE
VLDVSMAGGIGDPEDLECRINNLPGVLENGLFVNLTDEVLVGQISDGVAGVRRLQRRE
EEEEEECCCCCCCCCCEEEECCCCCHHHCCEEEEEEHHHEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ADLQTQMKQAVAAAAVEQIKDGMVLGLGSGSTAALMIQALGAKLASGELREIVGVTTSF
CCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCHHCCCHHHHHHHCCCCC
QGEVMAAELGIPLRNLTAVDRIDLAIDGADEVDPSFQLIKGGGACHVQEKLVASRADRFV
CCCEEEEECCCCHHHCCHHHEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEE
VVVDSTKIVDRLNLGFLLPVEVLPGAWRQVQGRLAELGGIADLRMAQCKAGPVVTDQGNL
EEECCHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCE
VLDVSMAGGIGDPEDLECRINNLPGVLENGLFVNLTDEVLVGQISDGVAGVRRLQRRE
EEEEEECCCCCCCCCCEEEECCCCCHHHCCEEEEEEHHHEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA