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The map label for this gene is trxB [H]

Identifier: 124022094

GI number: 124022094

Start: 386345

End: 387298

Strand: Direct

Name: trxB [H]

Synonym: P9303_03841

Alternate gene names: 124022094

Gene position: 386345-387298 (Clockwise)

Preceding gene: 124022093

Following gene: 124022097

Centisome position: 14.4

GC content: 52.31

Gene sequence:

>954_bases
TTGGAAACAATCGAAGCCGATGTGGTGATCGTGGGTGGTGGCCCAGCTGGTTGCAGCTGCGCGCTTTACACATCGCGTGC
CGATTTGAAGACAGTCATCCTTGATAAGAATCCTGATGTAGGTGCCTTGGCGATTACTCATCAGATCGCTAACTATCCAG
GCGTTTCCAGCGAGATGAGTGGCGAAGCGCTACTGGCTTTGATGCGCGAGCAGGCCGTTTCCTTTGGCAGTGATTATCGT
CGTGCCCAGGTTTTTGGTGTGGACGTGAATGGTGAATGGAAGACGGTGTATACCCCTGAAGGGACTTTTAAGGCAAGGGC
GCTGGTTGTAGCGACTGGAGCTTTGGGGCGCCCAGCATCATTTAAGGGAGAGGCAGAGTACCTTGGCCGCGGCGTGAGCT
ATTGCGCTACCTGTGATGGTGCCTTTTACAAAGGACGTGAGGTAGCTGTTGTTGGGGCAAACAAAGAGGCAGTTGAGGAA
GGACAGGTGCTGACCAAGTTCGCCTCGACAGTGCATTGGCTTACCACGAGTGACCCGAAGGAAGATGACGTGCACGCGCA
AGCGTTGATGACTCAGCCAAATGTTCAACACTGGAGCCGCACAAGATTGATGTTGATCGAGGGAGATGACGCTGGCGTGA
CTGGCATCAAGTTGAAAAATCGGGCTCAGGAGACAGAGCAGGACTTGGCCGTTGAAGGTGTGTTTGTTTACATGAGTGGC
TCTAAGCCAATCACTGATTTCTTAGGTGATCAGGTGGCTTTTAAAGAGGATGGAGGCGTCGTGGTAGATGACTTTATGGC
CACAACAGTTGACGGGGTATGGGCTATTGGTGATATTCGTAACACCCCGTTTAAGCAGGCGGTGGTGGCTGCATCAGACG
GATGTATTGCAGCAATGGCGATCGATCGATTCCTTAATAGCCGCAAGGGGATTCGTGTTGATTGGGTGCATTAG

Upstream 100 bases:

>100_bases
GGGGTGGCTTTTTGGGATTGTTGTCTGAACGGCGCATCCTGATCTGAAGCTGATGAGCTGTTGAGAGCAGCTTTGACACC
CTGCTGGAGACCTTTGCCTC

Downstream 100 bases:

>100_bases
TGAGGACGCACCTTCGACCAGGCCTTGTCTTGCCGACCTTTCCTCCATGGCTGATCAATTATTCGATCAGGAAATTGACT
TTAAAGTTTGAAGAATGAGT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
METIEADVVIVGGGPAGCSCALYTSRADLKTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLALMREQAVSFGSDYR
RAQVFGVDVNGEWKTVYTPEGTFKARALVVATGALGRPASFKGEAEYLGRGVSYCATCDGAFYKGREVAVVGANKEAVEE
GQVLTKFASTVHWLTTSDPKEDDVHAQALMTQPNVQHWSRTRLMLIEGDDAGVTGIKLKNRAQETEQDLAVEGVFVYMSG
SKPITDFLGDQVAFKEDGGVVVDDFMATTVDGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRFLNSRKGIRVDWVH

Sequences:

>Translated_317_residues
METIEADVVIVGGGPAGCSCALYTSRADLKTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLALMREQAVSFGSDYR
RAQVFGVDVNGEWKTVYTPEGTFKARALVVATGALGRPASFKGEAEYLGRGVSYCATCDGAFYKGREVAVVGANKEAVEE
GQVLTKFASTVHWLTTSDPKEDDVHAQALMTQPNVQHWSRTRLMLIEGDDAGVTGIKLKNRAQETEQDLAVEGVFVYMSG
SKPITDFLGDQVAFKEDGGVVVDDFMATTVDGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRFLNSRKGIRVDWVH
>Mature_317_residues
METIEADVVIVGGGPAGCSCALYTSRADLKTVILDKNPDVGALAITHQIANYPGVSSEMSGEALLALMREQAVSFGSDYR
RAQVFGVDVNGEWKTVYTPEGTFKARALVVATGALGRPASFKGEAEYLGRGVSYCATCDGAFYKGREVAVVGANKEAVEE
GQVLTKFASTVHWLTTSDPKEDDVHAQALMTQPNVQHWSRTRLMLIEGDDAGVTGIKLKNRAQETEQDLAVEGVFVYMSG
SKPITDFLGDQVAFKEDGGVVVDDFMATTVDGVWAIGDIRNTPFKQAVVAASDGCIAAMAIDRFLNSRKGIRVDWVH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=32.6984126984127, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=30.1948051948052, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=31.8885448916409, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=321, Percent_Identity=30.2180685358255, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33996; Mature: 33996

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIEADVVIVGGGPAGCSCALYTSRADLKTVILDKNPDVGALAITHQIANYPGVSSEMS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHHCCCCCCCCCC
GEALLALMREQAVSFGSDYRRAQVFGVDVNGEWKTVYTPEGTFKARALVVATGALGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCC
FKGEAEYLGRGVSYCATCDGAFYKGREVAVVGANKEAVEEGQVLTKFASTVHWLTTSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
EDDVHAQALMTQPNVQHWSRTRLMLIEGDDAGVTGIKLKNRAQETEQDLAVEGVFVYMSG
CCCCHHHHEECCCCCCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHCEEEEEEEEEEEC
SKPITDFLGDQVAFKEDGGVVVDDFMATTVDGVWAIGDIRNTPFKQAVVAASDGCIAAMA
CCCHHHHCCCCEEEECCCCEEEECHHHHHHCCEEEECCCCCCCHHHEEEECCCCCCHHHH
IDRFLNSRKGIRVDWVH
HHHHHHCCCCEEEEEEC
>Mature Secondary Structure
METIEADVVIVGGGPAGCSCALYTSRADLKTVILDKNPDVGALAITHQIANYPGVSSEMS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEHHHCCCCCCCCCC
GEALLALMREQAVSFGSDYRRAQVFGVDVNGEWKTVYTPEGTFKARALVVATGALGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCC
FKGEAEYLGRGVSYCATCDGAFYKGREVAVVGANKEAVEEGQVLTKFASTVHWLTTSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
EDDVHAQALMTQPNVQHWSRTRLMLIEGDDAGVTGIKLKNRAQETEQDLAVEGVFVYMSG
CCCCHHHHEECCCCCCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHCEEEEEEEEEEEC
SKPITDFLGDQVAFKEDGGVVVDDFMATTVDGVWAIGDIRNTPFKQAVVAASDGCIAAMA
CCCHHHHCCCCEEEECCCCEEEECHHHHHHCCEEEECCCCCCCHHHEEEECCCCCCHHHH
IDRFLNSRKGIRVDWVH
HHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]