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The map label for this gene is dap2 [H]

Identifier: 124022017

GI number: 124022017

Start: 321324

End: 323282

Strand: Reverse

Name: dap2 [H]

Synonym: P9303_03061

Alternate gene names: 124022017

Gene position: 323282-321324 (Counterclockwise)

Preceding gene: 124022018

Following gene: 124022011

Centisome position: 12.05

GC content: 55.64

Gene sequence:

>1959_bases
ATGGAAAGCACCAGCCATCACCAGCGAAACCCGAAGCAAACCACTCAACCTCTTTCTGCCAGACGCGCTCTCGGACAAAC
ACCCACCCTCAAAGAACCGCGCCTGATTGATGACTGGGTGCTTTGGCTGGAGCAACGTCCTCAGGAACATGGTCGCACCA
CTGCCCTTATCCGTCCCTGGGGTCAATCTGACCACCCCCCCCAAGAGCTGACACCTGCCCCAGCCAACCTGCGTAGTCGT
ATTCACGATTACGGAGGAGGGGTTCTAGCAACAGCCTGCCAAGACAACCAGCTACTGATGGCCTGGATCGATGATGCCGA
TGGCTGCCTCTGGTTCCAGCGCTGGCAGGGCCTCAACCAGGCCACAAAAGGTAAGAAGGCATTATCTCCGCTCAAGCCGC
CGCTTCGCCTCTCAAAACCAAACGATGCCCAACTTGCTGATGGTCTGATTGACCTCCCACGACAGCGCTGGCTCGGAATC
ATGGAAGCAGACAAGCGGGACTGGCTGGTGACCTTCTCCCTCAACCATGAGAACCAGGCTGCCACGGTGTTGCATCGCCC
TGCTGATTTTGCTGGTTACGCGATCCTCAGCCCGAATGGAGATCAACTGGCCTGGGTGGAATGGCAACAACCGGCCATGC
CCTGGGAGGCAAGCCAACTCTGGTGGGCCAGCCTCGACCCTGCGGGTTTGATCCAAAGCTCGGCCTGTCTAGCTGGTAGC
AAACCACTTGATCACAAACAAACGTCCGTTTTCCAGCCCCTTTGGCTACCCAATGGAGAGCTGGTTGTCAGCGAAGACAG
CAGCGGCTGGTGGAATCTGATGGTGGCAAAGCTGACGACTGACCCCACTGTCCAACCCACTTGGCGACGCCCCTGGCCAC
TTTCAGCCGAAACCGGCATGCCGCAGTGGGTTTATGGCATGAGCAGCAGCGCATGGGATGGAGAACAAATTCTGACCGCC
GTCTGTGAACAAGGTTCTTGGAGGCTGAGCCGCTTGGCCGATGATGGACAGATCAGCACCATCAACCAACCTTTTGATGA
TCTAAATGGTCTGCAGGCACAGGAAGGTCGAGCCGTAGCCATCGCTAGCAATGCCACCACGAGCCCTGGGCTACTAGAGC
TCAACCTCAACTGTGGCAGCTGGAAGCACACCCCAGCCAATGAGCCTTTACTGAATGCTGATGCAATCAGCGTTGCGGAA
CCTATCTGGTTTGAAGGCTGCCATGGCCAGGCAACCCATGCCTGGTATTACCCGCCAATCAATGGCAGCAAAGGCCCTGC
GCCACTACTTGTCAAAAGCCATAGCGGTCCTACCAGCATGGCCAACCACGGTCTAAGCCTCAGCATTCAGTTCTGGACAT
GCAGAGGCTGGGGAGTGGTGGATGTGAACTATGGCGGCTCCACTGGATTTGGCCGTGCATACCGCGAACGCCTACGGGGA
GGCTGGGGTGAGACAGACGTAACGGATTGCGCACAAGCAGCACTTGCACTAGTGAAATGCAACAAGGCAAACCCAACACA
AATCGCCATTGAAGGAGGCAGTGCCGGTGGATTTACCACCCTGGCCTGCCTTTGTTTCACAGATGTCTTTCGCGCTGCTG
CCTGCCGTTATGCAGTGAGTGATCTCACCGCCATGGCAGAAGACACCCATCGATTTGAAGCGCGATACCTCGATCACCTA
GTAGGCCGTTGGCCCGACCAAAGACAACTTTACGAAAACCGCTCACCTCTCCTGCATGCCAACAAGATCCAATGCCCAGT
GATCTTCTTTCAGGGACTTCAAGACAAAGTGGTTCCTCCAGATCAAACAGAACGGATGGCCAATGCCTTAAAAGAAAACG
GCATACCAGTTGAACTACACATTTTTGAGCAGGAAGGCCACGGCTTTCGCGACAGTGCTGTCAAGATCAAAGTCTTAGAA
GCAACTGAGCAATTCTTCCGCCGCCACCTAAAGCTCTAG

Upstream 100 bases:

>100_bases
CCGTACGTGCCAGCTGAGCGAAGCTTCGAGCCAAAGAAAAGTCTCAGCATCAGTTGATTGAGTTTAGGCAACTCCACCGC
ACATCAGACCCCAAACCGCC

Downstream 100 bases:

>100_bases
CTGTGCTCTCTTAAGAAGCCGATCGTCGAAACCAATTCCTCAGCAAAACGATCGACTTCTTCTGGTGTATTGGTGAAGCT
CAAGCTGGCACGAGCTGATC

Product: esterase/lipase/thioesterase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MESTSHHQRNPKQTTQPLSARRALGQTPTLKEPRLIDDWVLWLEQRPQEHGRTTALIRPWGQSDHPPQELTPAPANLRSR
IHDYGGGVLATACQDNQLLMAWIDDADGCLWFQRWQGLNQATKGKKALSPLKPPLRLSKPNDAQLADGLIDLPRQRWLGI
MEADKRDWLVTFSLNHENQAATVLHRPADFAGYAILSPNGDQLAWVEWQQPAMPWEASQLWWASLDPAGLIQSSACLAGS
KPLDHKQTSVFQPLWLPNGELVVSEDSSGWWNLMVAKLTTDPTVQPTWRRPWPLSAETGMPQWVYGMSSSAWDGEQILTA
VCEQGSWRLSRLADDGQISTINQPFDDLNGLQAQEGRAVAIASNATTSPGLLELNLNCGSWKHTPANEPLLNADAISVAE
PIWFEGCHGQATHAWYYPPINGSKGPAPLLVKSHSGPTSMANHGLSLSIQFWTCRGWGVVDVNYGGSTGFGRAYRERLRG
GWGETDVTDCAQAALALVKCNKANPTQIAIEGGSAGGFTTLACLCFTDVFRAAACRYAVSDLTAMAEDTHRFEARYLDHL
VGRWPDQRQLYENRSPLLHANKIQCPVIFFQGLQDKVVPPDQTERMANALKENGIPVELHIFEQEGHGFRDSAVKIKVLE
ATEQFFRRHLKL

Sequences:

>Translated_652_residues
MESTSHHQRNPKQTTQPLSARRALGQTPTLKEPRLIDDWVLWLEQRPQEHGRTTALIRPWGQSDHPPQELTPAPANLRSR
IHDYGGGVLATACQDNQLLMAWIDDADGCLWFQRWQGLNQATKGKKALSPLKPPLRLSKPNDAQLADGLIDLPRQRWLGI
MEADKRDWLVTFSLNHENQAATVLHRPADFAGYAILSPNGDQLAWVEWQQPAMPWEASQLWWASLDPAGLIQSSACLAGS
KPLDHKQTSVFQPLWLPNGELVVSEDSSGWWNLMVAKLTTDPTVQPTWRRPWPLSAETGMPQWVYGMSSSAWDGEQILTA
VCEQGSWRLSRLADDGQISTINQPFDDLNGLQAQEGRAVAIASNATTSPGLLELNLNCGSWKHTPANEPLLNADAISVAE
PIWFEGCHGQATHAWYYPPINGSKGPAPLLVKSHSGPTSMANHGLSLSIQFWTCRGWGVVDVNYGGSTGFGRAYRERLRG
GWGETDVTDCAQAALALVKCNKANPTQIAIEGGSAGGFTTLACLCFTDVFRAAACRYAVSDLTAMAEDTHRFEARYLDHL
VGRWPDQRQLYENRSPLLHANKIQCPVIFFQGLQDKVVPPDQTERMANALKENGIPVELHIFEQEGHGFRDSAVKIKVLE
ATEQFFRRHLKL
>Mature_652_residues
MESTSHHQRNPKQTTQPLSARRALGQTPTLKEPRLIDDWVLWLEQRPQEHGRTTALIRPWGQSDHPPQELTPAPANLRSR
IHDYGGGVLATACQDNQLLMAWIDDADGCLWFQRWQGLNQATKGKKALSPLKPPLRLSKPNDAQLADGLIDLPRQRWLGI
MEADKRDWLVTFSLNHENQAATVLHRPADFAGYAILSPNGDQLAWVEWQQPAMPWEASQLWWASLDPAGLIQSSACLAGS
KPLDHKQTSVFQPLWLPNGELVVSEDSSGWWNLMVAKLTTDPTVQPTWRRPWPLSAETGMPQWVYGMSSSAWDGEQILTA
VCEQGSWRLSRLADDGQISTINQPFDDLNGLQAQEGRAVAIASNATTSPGLLELNLNCGSWKHTPANEPLLNADAISVAE
PIWFEGCHGQATHAWYYPPINGSKGPAPLLVKSHSGPTSMANHGLSLSIQFWTCRGWGVVDVNYGGSTGFGRAYRERLRG
GWGETDVTDCAQAALALVKCNKANPTQIAIEGGSAGGFTTLACLCFTDVFRAAACRYAVSDLTAMAEDTHRFEARYLDHL
VGRWPDQRQLYENRSPLLHANKIQCPVIFFQGLQDKVVPPDQTERMANALKENGIPVELHIFEQEGHGFRDSAVKIKVLE
ATEQFFRRHLKL

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=239, Percent_Identity=25.9414225941423, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17552908, Length=588, Percent_Identity=29.7619047619048, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI25144540, Length=212, Percent_Identity=30.188679245283, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144537, Length=212, Percent_Identity=30.6603773584906, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25149159, Length=240, Percent_Identity=25.4166666666667, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25144543, Length=102, Percent_Identity=37.2549019607843, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 72431; Mature: 72431

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTSHHQRNPKQTTQPLSARRALGQTPTLKEPRLIDDWVLWLEQRPQEHGRTTALIRPW
CCCCCCCCCCCHHHHCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHCCCEEEEEECC
GQSDHPPQELTPAPANLRSRIHDYGGGVLATACQDNQLLMAWIDDADGCLWFQRWQGLNQ
CCCCCCCHHCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEHHHHHCCCCH
ATKGKKALSPLKPPLRLSKPNDAQLADGLIDLPRQRWLGIMEADKRDWLVTFSLNHENQA
HHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCEECCCCCEEEEEEECCCCCE
ATVLHRPADFAGYAILSPNGDQLAWVEWQQPAMPWEASQLWWASLDPAGLIQSSACLAGS
EEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHCCHHHCCC
KPLDHKQTSVFQPLWLPNGELVVSEDSSGWWNLMVAKLTTDPTVQPTWRRPWPLSAETGM
CCCCCCHHHCCCEEECCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
PQWVYGMSSSAWDGEQILTAVCEQGSWRLSRLADDGQISTINQPFDDLNGLQAQEGRAVA
CCEEECCCCCCCCHHHHHHHHHHCCCCEEHHCCCCCCEEECCCCHHHHCCCCCCCCCEEE
IASNATTSPGLLELNLNCGSWKHTPANEPLLNADAISVAEPIWFEGCHGQATHAWYYPPI
EECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCEEEECCCC
NGSKGPAPLLVKSHSGPTSMANHGLSLSIQFWTCRGWGVVDVNYGGSTGFGRAYRERLRG
CCCCCCCCEEEECCCCCHHHHCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCC
GWGETDVTDCAQAALALVKCNKANPTQIAIEGGSAGGFTTLACLCFTDVFRAAACRYAVS
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTAMAEDTHRFEARYLDHLVGRWPDQRQLYENRSPLLHANKIQCPVIFFQGLQDKVVPP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCCCEEEEECCCCCCCCCC
DQTERMANALKENGIPVELHIFEQEGHGFRDSAVKIKVLEATEQFFRRHLKL
CHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MESTSHHQRNPKQTTQPLSARRALGQTPTLKEPRLIDDWVLWLEQRPQEHGRTTALIRPW
CCCCCCCCCCCHHHHCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHCCCEEEEEECC
GQSDHPPQELTPAPANLRSRIHDYGGGVLATACQDNQLLMAWIDDADGCLWFQRWQGLNQ
CCCCCCCHHCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEHHHHHCCCCH
ATKGKKALSPLKPPLRLSKPNDAQLADGLIDLPRQRWLGIMEADKRDWLVTFSLNHENQA
HHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCEECCCCCEEEEEEECCCCCE
ATVLHRPADFAGYAILSPNGDQLAWVEWQQPAMPWEASQLWWASLDPAGLIQSSACLAGS
EEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHCCHHHCCC
KPLDHKQTSVFQPLWLPNGELVVSEDSSGWWNLMVAKLTTDPTVQPTWRRPWPLSAETGM
CCCCCCHHHCCCEEECCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
PQWVYGMSSSAWDGEQILTAVCEQGSWRLSRLADDGQISTINQPFDDLNGLQAQEGRAVA
CCEEECCCCCCCCHHHHHHHHHHCCCCEEHHCCCCCCEEECCCCHHHHCCCCCCCCCEEE
IASNATTSPGLLELNLNCGSWKHTPANEPLLNADAISVAEPIWFEGCHGQATHAWYYPPI
EECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCEEEECCCC
NGSKGPAPLLVKSHSGPTSMANHGLSLSIQFWTCRGWGVVDVNYGGSTGFGRAYRERLRG
CCCCCCCCEEEECCCCCHHHHCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCC
GWGETDVTDCAQAALALVKCNKANPTQIAIEGGSAGGFTTLACLCFTDVFRAAACRYAVS
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTAMAEDTHRFEARYLDHLVGRWPDQRQLYENRSPLLHANKIQCPVIFFQGLQDKVVPP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCCCEEEEECCCCCCCCCC
DQTERMANALKENGIPVELHIFEQEGHGFRDSAVKIKVLEATEQFFRRHLKL
CHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]