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The map label for this gene is 124021990

Identifier: 124021990

GI number: 124021990

Start: 289539

End: 291653

Strand: Reverse

Name: 124021990

Synonym: P9303_02771

Alternate gene names: NA

Gene position: 291653-289539 (Counterclockwise)

Preceding gene: 124021991

Following gene: 124021989

Centisome position: 10.87

GC content: 42.46

Gene sequence:

>2115_bases
ATGCTAGTGGAAAAGGCAATAGAAGCTGAACAAGGGAACAGCTTTACACTCGGACTCCTGGCGACGATTGAAAAAGCATT
AGGCAACATTGACAGAGCCTCAGAACTTTTCGAAAAATCAATAAATATCGACCAAAGAAATCCAGATATACTGCACAACT
ATTCCATTTTATTGGCAGAAAAAGACCCTTCAAAAGCAGTAAATATATCGAATAGAGCGCTAGCAATGTCGCCAGAAAAC
AGCTATTATCTCGAAAGAAATGGATACTTAAAATGGAAGCAGGGCGATCTAGACAACGCACTCGAATCGACAATAAAAGC
CATAGAGCTCAGCCCTGATCTAATCGATGCCCACTTGAACCTGGGCGGCATCTTTAAAGATCTTGGAAACCTTGATCAGG
CTCTTGCTTCTACTCTCAAATCTCTGGAGCTCAAATCTGATAACTCTAAAGCTCACATGAACCTGGGCGGCATTTATAAA
GATCTCGGCAACCTTGATCAAGCTCTTGCTTCTACTCTCAAATCTCTGGAACTCAAGCCTGACAACCTCAGTGCCCTGAA
TAACCTAAACGGATTTATCGACCAGCTAACGCTCAGCCCCAGCAATGCGCAGAATCTTACAAAAGCATACGAATTGCTGA
TTAATTTAGACAATATCTCGCACAGCAAACTATCCATGATCTTTATTCAAACTTTCCTTCCAGCCATCCAAGAGGCTGCT
AAATTTAATCCCATCATCTCAGCAGAAAACAATGCTCTCACCAATCTCGCTGGGGATTGGCGACTAAGAAAGTCCCTTAC
ATTACTGATCCCACCTCATCAAGCTATTGAGCACTTCCTGAGGCGCCTAAGAAAAGAACTCGTTGGACTTGCAGCCAATC
AGCAAGTAATCCCAGAAATCTTAAGAGCGCTCACCGAATCATTAGCCACACAGTGCTTCCTTAATGAATACGTATACGCC
CAATCACCAGAAGAAGAAGTGTTTGTCAATCAACTGATCGAACTTATAAACGATAACCAGAATTCATTCAATCAATACCT
TGCCGTTCTTGCCTGCTACGCCCCCATCTATCGACTCAGCCTTAAGCAAGATTGGCTGAAAGATTATCCAACCTCTAGCC
ATGAGAGCAGAGCGCTCATCCAAACCCAACTAGAAGAGCCGAATGAAGAAGAAAAAATCAAAAGCGCAATCCTTACCAGT
TCAGTGATTAATGACGCAGTTTCGTCCAAAGTCAAGGCTATGTATGAAGAGAATCCATACCCTCGATATCGCTATGCGGA
CCATACAAGCAACTCATTAGCCAAGACCCCATCAGAAACCATCAAACTAGAGTCAACAAAATACAATCTTCAATTCTCAG
AAGAGTTAATCGCAAATCATTCACACCCAAAAGTGCTCATTGCCGGCTGTGGAACTGGCAATCAAGTCATCAATGCCAGT
CGCTACAAAAATGCCCAGATCACAGCAATTGATCTCAGCCGCCCAAGCCTGGCATATGCCATCAGGAAAGCAGAGGGTTA
CAACATGAACAATGTGTCTTTTAAAATAATAGATATTCTACATGTAGCCAACCTTAAGGCAACATTTGATATCATTGAGT
GTAGCGGTGTTCTTCATCACATGGAAGATCCCGGCAAAGGGATCTCAGCATTAAAAAGCCAACTTGCACATGGCGGCTAT
ATTAAACTTGCCTTATACAGCGAAATTGCCAGGCAACAAATCGTAGAAGCCCGAAATCAGATTAAACAGCTAGGATTCAA
AAGCACACCAAATGGCATCAGAGATTTTCGCCAACAAGTTTTCCAGGGTCAATTGAAGGAATTATCAGGGCTGTCCAAAA
TCTGGGTTGACTTTTATTCACTCTCAGAATGCCGAGATCTCTGCTTCCATGTACAAGAACATCGATTCACAGCAGAGTCG
ATTCAACATCTTTTAGACACTCAGGGATTAATCTTTTGTGGATTCATGCTGCCAAAGACAATCCGCAGTTCTTACCAAGA
ACAATACCCGGATGATTCTGAAATGACATCTCTTGAAAACTGGGGAGAATTTGAAAAAAAGCATCCAACAACCTTTAGAG
GAATGTACCAGTTCTGGGCTTATAAGCATTCTTAG

Upstream 100 bases:

>100_bases
TAAACAAAACAAAACAAAACAACTGAGAAAATTAGAAATAGAGGGGGCAATAAAGCAATCACTCATGGCTTACAAACAAG
GGAACCTAAGGAACGCGAAG

Downstream 100 bases:

>100_bases
ATCAGTTCAAATGCATGGGATATTGTGCTTCTTATATTCCTTACGAATCGTCTCCTCAATCCCTTCCTGGTACAACGCAG
AAAGATTCAATCACCATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MLVEKAIEAEQGNSFTLGLLATIEKALGNIDRASELFEKSINIDQRNPDILHNYSILLAEKDPSKAVNISNRALAMSPEN
SYYLERNGYLKWKQGDLDNALESTIKAIELSPDLIDAHLNLGGIFKDLGNLDQALASTLKSLELKSDNSKAHMNLGGIYK
DLGNLDQALASTLKSLELKPDNLSALNNLNGFIDQLTLSPSNAQNLTKAYELLINLDNISHSKLSMIFIQTFLPAIQEAA
KFNPIISAENNALTNLAGDWRLRKSLTLLIPPHQAIEHFLRRLRKELVGLAANQQVIPEILRALTESLATQCFLNEYVYA
QSPEEEVFVNQLIELINDNQNSFNQYLAVLACYAPIYRLSLKQDWLKDYPTSSHESRALIQTQLEEPNEEEKIKSAILTS
SVINDAVSSKVKAMYEENPYPRYRYADHTSNSLAKTPSETIKLESTKYNLQFSEELIANHSHPKVLIAGCGTGNQVINAS
RYKNAQITAIDLSRPSLAYAIRKAEGYNMNNVSFKIIDILHVANLKATFDIIECSGVLHHMEDPGKGISALKSQLAHGGY
IKLALYSEIARQQIVEARNQIKQLGFKSTPNGIRDFRQQVFQGQLKELSGLSKIWVDFYSLSECRDLCFHVQEHRFTAES
IQHLLDTQGLIFCGFMLPKTIRSSYQEQYPDDSEMTSLENWGEFEKKHPTTFRGMYQFWAYKHS

Sequences:

>Translated_704_residues
MLVEKAIEAEQGNSFTLGLLATIEKALGNIDRASELFEKSINIDQRNPDILHNYSILLAEKDPSKAVNISNRALAMSPEN
SYYLERNGYLKWKQGDLDNALESTIKAIELSPDLIDAHLNLGGIFKDLGNLDQALASTLKSLELKSDNSKAHMNLGGIYK
DLGNLDQALASTLKSLELKPDNLSALNNLNGFIDQLTLSPSNAQNLTKAYELLINLDNISHSKLSMIFIQTFLPAIQEAA
KFNPIISAENNALTNLAGDWRLRKSLTLLIPPHQAIEHFLRRLRKELVGLAANQQVIPEILRALTESLATQCFLNEYVYA
QSPEEEVFVNQLIELINDNQNSFNQYLAVLACYAPIYRLSLKQDWLKDYPTSSHESRALIQTQLEEPNEEEKIKSAILTS
SVINDAVSSKVKAMYEENPYPRYRYADHTSNSLAKTPSETIKLESTKYNLQFSEELIANHSHPKVLIAGCGTGNQVINAS
RYKNAQITAIDLSRPSLAYAIRKAEGYNMNNVSFKIIDILHVANLKATFDIIECSGVLHHMEDPGKGISALKSQLAHGGY
IKLALYSEIARQQIVEARNQIKQLGFKSTPNGIRDFRQQVFQGQLKELSGLSKIWVDFYSLSECRDLCFHVQEHRFTAES
IQHLLDTQGLIFCGFMLPKTIRSSYQEQYPDDSEMTSLENWGEFEKKHPTTFRGMYQFWAYKHS
>Mature_704_residues
MLVEKAIEAEQGNSFTLGLLATIEKALGNIDRASELFEKSINIDQRNPDILHNYSILLAEKDPSKAVNISNRALAMSPEN
SYYLERNGYLKWKQGDLDNALESTIKAIELSPDLIDAHLNLGGIFKDLGNLDQALASTLKSLELKSDNSKAHMNLGGIYK
DLGNLDQALASTLKSLELKPDNLSALNNLNGFIDQLTLSPSNAQNLTKAYELLINLDNISHSKLSMIFIQTFLPAIQEAA
KFNPIISAENNALTNLAGDWRLRKSLTLLIPPHQAIEHFLRRLRKELVGLAANQQVIPEILRALTESLATQCFLNEYVYA
QSPEEEVFVNQLIELINDNQNSFNQYLAVLACYAPIYRLSLKQDWLKDYPTSSHESRALIQTQLEEPNEEEKIKSAILTS
SVINDAVSSKVKAMYEENPYPRYRYADHTSNSLAKTPSETIKLESTKYNLQFSEELIANHSHPKVLIAGCGTGNQVINAS
RYKNAQITAIDLSRPSLAYAIRKAEGYNMNNVSFKIIDILHVANLKATFDIIECSGVLHHMEDPGKGISALKSQLAHGGY
IKLALYSEIARQQIVEARNQIKQLGFKSTPNGIRDFRQQVFQGQLKELSGLSKIWVDFYSLSECRDLCFHVQEHRFTAES
IQHLLDTQGLIFCGFMLPKTIRSSYQEQYPDDSEMTSLENWGEFEKKHPTTFRGMYQFWAYKHS

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2067c [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=171, Percent_Identity=29.8245614035088, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI32307150, Length=171, Percent_Identity=29.8245614035088, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17647755, Length=195, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585827, Length=195, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585829, Length=195, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 79329; Mature: 79329

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVEKAIEAEQGNSFTLGLLATIEKALGNIDRASELFEKSINIDQRNPDILHNYSILLAE
CCCHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEECEEEEEEE
KDPSKAVNISNRALAMSPENSYYLERNGYLKWKQGDLDNALESTIKAIELSPDLIDAHLN
CCCCCCCCCCCCEEEECCCCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCC
LGGIFKDLGNLDQALASTLKSLELKSDNSKAHMNLGGIYKDLGNLDQALASTLKSLELKP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
DNLSALNNLNGFIDQLTLSPSNAQNLTKAYELLINLDNISHSKLSMIFIQTFLPAIQEAA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KFNPIISAENNALTNLAGDWRLRKSLTLLIPPHQAIEHFLRRLRKELVGLAANQQVIPEI
HCCCCEECCCCCHHHCCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LRALTESLATQCFLNEYVYAQSPEEEVFVNQLIELINDNQNSFNQYLAVLACYAPIYRLS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKQDWLKDYPTSSHESRALIQTQLEEPNEEEKIKSAILTSSVINDAVSSKVKAMYEENPY
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRYRYADHTSNSLAKTPSETIKLESTKYNLQFSEELIANHSHPKVLIAGCGTGNQVINAS
CCCEECCCCCCCHHCCCCHHEEEECEEECCEEHHHHHCCCCCCEEEEEECCCCCHHCCHH
RYKNAQITAIDLSRPSLAYAIRKAEGYNMNNVSFKIIDILHVANLKATFDIIECSGVLHH
HCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHH
MEDPGKGISALKSQLAHGGYIKLALYSEIARQQIVEARNQIKQLGFKSTPNGIRDFRQQV
CCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FQGQLKELSGLSKIWVDFYSLSECRDLCFHVQEHRFTAESIQHLLDTQGLIFCGFMLPKT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
IRSSYQEQYPDDSEMTSLENWGEFEKKHPTTFRGMYQFWAYKHS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVEKAIEAEQGNSFTLGLLATIEKALGNIDRASELFEKSINIDQRNPDILHNYSILLAE
CCCHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEECEEEEEEE
KDPSKAVNISNRALAMSPENSYYLERNGYLKWKQGDLDNALESTIKAIELSPDLIDAHLN
CCCCCCCCCCCCEEEECCCCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCC
LGGIFKDLGNLDQALASTLKSLELKSDNSKAHMNLGGIYKDLGNLDQALASTLKSLELKP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
DNLSALNNLNGFIDQLTLSPSNAQNLTKAYELLINLDNISHSKLSMIFIQTFLPAIQEAA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KFNPIISAENNALTNLAGDWRLRKSLTLLIPPHQAIEHFLRRLRKELVGLAANQQVIPEI
HCCCCEECCCCCHHHCCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LRALTESLATQCFLNEYVYAQSPEEEVFVNQLIELINDNQNSFNQYLAVLACYAPIYRLS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKQDWLKDYPTSSHESRALIQTQLEEPNEEEKIKSAILTSSVINDAVSSKVKAMYEENPY
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRYRYADHTSNSLAKTPSETIKLESTKYNLQFSEELIANHSHPKVLIAGCGTGNQVINAS
CCCEECCCCCCCHHCCCCHHEEEECEEECCEEHHHHHCCCCCCEEEEEECCCCCHHCCHH
RYKNAQITAIDLSRPSLAYAIRKAEGYNMNNVSFKIIDILHVANLKATFDIIECSGVLHH
HCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHH
MEDPGKGISALKSQLAHGGYIKLALYSEIARQQIVEARNQIKQLGFKSTPNGIRDFRQQV
CCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FQGQLKELSGLSKIWVDFYSLSECRDLCFHVQEHRFTAESIQHLLDTQGLIFCGFMLPKT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
IRSSYQEQYPDDSEMTSLENWGEFEKKHPTTFRGMYQFWAYKHS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041005; 1901865 [H]