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The map label for this gene is xseA [H]

Identifier: 124021951

GI number: 124021951

Start: 253492

End: 254649

Strand: Reverse

Name: xseA [H]

Synonym: P9303_02381

Alternate gene names: 124021951

Gene position: 254649-253492 (Counterclockwise)

Preceding gene: 124021952

Following gene: 124021950

Centisome position: 9.49

GC content: 52.68

Gene sequence:

>1158_bases
TTGACCGCTGAATCCCTTCCAAACTATTCAGTCCGCGATCTCAACGCGGCTATTGGCACTCTGCTGGAACGTGGCTTTGC
ACCTCGCTTTCTGGTGGAAGCGTCAGTCTCCAAGCCACAGATCAAAAAAGGTCATCTCTGGCTAACTCTGACTGACGGCA
ACGCAAGTATCACGGCAGTGGCTTGGGCTTCCAAGCTGCAGCAACTCACCTACAGGCCTGCAGAAGGGGATGGGGTAACG
GTTGTCGGCAAGCTCAACTTCTGGGCAACCCGAGCAAGCCTGGCCGTGCAGGTCATCGACCTGCGTCCGTCCCTATCGAC
GGTGCTGCGTCAGTTCGAAATTGTGAAAGCCCTGCTACTGAAAGAGGGCATCATCGACGAATCGAAACGGAAAGCGTTAC
CAAAATATCCAGAGGTTATAGCCATCTTGACCAGCGTGCCCAGTTCCGCCCTAGCAGACATGCTGCGTACAGCAAAAGAG
CGCTGGCCTCTAACTCAATTGCTGATCATTCCAATTCCAGTCCAAGGTGGTGTAGCAAAACAAATCCAATCCGTTTTACG
TTCTCTGGCTAATCAACATGATGAGCTGGGGATTGCAGCGATCGTGCTGGCCAGAGGAGGTGGCAGTCGTGAAGACCTGA
TGGTGTTTGATGATGAAGACCTGTGCCGTGACCTAGCCAGTTTCCCAATACCGGTGGTGACTGGACTAGGGCATGAGGAT
GACCAAACAGTGGCTGATCTGGTTGCTGACCATAGAGCCGCGACGCCAACAGCAGCGATGGTGGCCCTGTTGCCCAGTCG
GGAATCAGCTCAAAATGTGCTGGTCCAACGCCGTCATCGACTTAAAGACCACTGCAATTGGCTCATTCGCAAAGAACTTG
AGCGGCTTGTAGATCGAGGCAAAGCGTTGGAGCGTCAACAACCGCTGAAACAGATCGAGCTTCAGCGCATTCACTTAAGC
CAAAAGCATCAGCTCCTCCAAGCTCTTTCACCAGAACTCTGGTTGATGCGCGGTTTTGCCATCGTGAAGAACAAGCAAGG
CAAAACTCTGCAAAGCGTGGGTGATGTATCTCTGCTGGACAATTTGACCATCCAACTCAGCGATGGCCAGATCAATGCCA
CCGCAGAAGAAATTAATCAGCAAAGGCCCTCGACATGA

Upstream 100 bases:

>100_bases
TTCACAATCGCATCCACCCAACTGGATCATGCTTGGGGGCAAGCTGTTGCTGCGCTTAGCGTCGTGATCTGCCTCTACTG
GGGCATGGCCTACCGACGCC

Downstream 100 bases:

>100_bases
TAAAAGCCACTTCATCATCTGAGAAGACGCCGAGAGATTCCGGCTCTAAACAGCAAAAGCACGCCATCAATACTGCGCAA
TCAACGCTAGATAGCATGCT

Product: exonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVT
VVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGIIDESKRKALPKYPEVIAILTSVPSSALADMLRTAKE
RWPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLVQRRHRLKDHCNWLIRKELERLVDRGKALERQQPLKQIELQRIHLS
QKHQLLQALSPELWLMRGFAIVKNKQGKTLQSVGDVSLLDNLTIQLSDGQINATAEEINQQRPST

Sequences:

>Translated_385_residues
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVT
VVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGIIDESKRKALPKYPEVIAILTSVPSSALADMLRTAKE
RWPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLVQRRHRLKDHCNWLIRKELERLVDRGKALERQQPLKQIELQRIHLS
QKHQLLQALSPELWLMRGFAIVKNKQGKTLQSVGDVSLLDNLTIQLSDGQINATAEEINQQRPST
>Mature_384_residues
TAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVTV
VGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGIIDESKRKALPKYPEVIAILTSVPSSALADMLRTAKER
WPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHEDD
QTVADLVADHRAATPTAAMVALLPSRESAQNVLVQRRHRLKDHCNWLIRKELERLVDRGKALERQQPLKQIELQRIHLSQ
KHQLLQALSPELWLMRGFAIVKNKQGKTLQSVGDVSLLDNLTIQLSDGQINATAEEINQQRPST

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=310, Percent_Identity=31.6129032258064, Blast_Score=147, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 42502; Mature: 42371

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHH
AWASKLQQLTYRPAEGDGVTVVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHH
KEGIIDESKRKALPKYPEVIAILTSVPSSALADMLRTAKERWPLTQLLIIPIPVQGGVAK
HHCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHH
QIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCC
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLVQRRHRLKDHCNWLIRKELERLVDRG
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALERQQPLKQIELQRIHLSQKHQLLQALSPELWLMRGFAIVKNKQGKTLQSVGDVSLLD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCHHHHHCCHHHHC
NLTIQLSDGQINATAEEINQQRPST
CEEEEEECCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHH
AWASKLQQLTYRPAEGDGVTVVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHH
KEGIIDESKRKALPKYPEVIAILTSVPSSALADMLRTAKERWPLTQLLIIPIPVQGGVAK
HHCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHH
QIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCC
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLVQRRHRLKDHCNWLIRKELERLVDRG
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALERQQPLKQIELQRIHLSQKHQLLQALSPELWLMRGFAIVKNKQGKTLQSVGDVSLLD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCHHHHHCCHHHHC
NLTIQLSDGQINATAEEINQQRPST
CEEEEEECCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA