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The map label for this gene is ruvB [H]

Identifier: 124021906

GI number: 124021906

Start: 211616

End: 212812

Strand: Direct

Name: ruvB [H]

Synonym: P9303_01931

Alternate gene names: 124021906

Gene position: 211616-212812 (Clockwise)

Preceding gene: 124021904

Following gene: 124021907

Centisome position: 7.89

GC content: 57.31

Gene sequence:

>1197_bases
ATGCCTTGCCAGACGGTTGTCCGCGAGCAGACGGTTGGCCGCGGCTCGAGCAGCAGCAGTCGCTTTTTTGTTTCCTCCCT
TGGCCATCTGCGTTTACCGATGCTTTCGACCCTATCCAGGGATCGGTACTCTTCCAACATGGCGATTGTGTCTTCCAGTG
CTGGCCGAGCTGATTCCCAGCCGCCAGCAGCAAAGTCTCGGGTGGTAGATGCTTCACCTTTGCCTGAAGAGGCCAGTCCA
GCTCGAGAAGATGGGCTTAGACCTAAGCGTTTGGAGGACTACATCGGTCAGCGTGAGCTGAAGCAGGTGTTGGGGATTGC
CGTTAAGGCGGCCATGGGCAGAGGCGATGCTTTGGATCATGTTTTGCTCTACGGCCCTCCGGGCTTGGGTAAAACCACCA
TGGCCATGGTTTTGGCTGAAGAATTGGGGGTTAAGTGTCGGGTTACCAGTGCGCCGGCTCTCGAGCGCCCTCGTGACATC
GTTGGTCTGTTGGTGAATCTGCAACCTCGCGAGGTTTTATTCATTGATGAGATTCACCGGCTCACAAGGGTTGCTGAAGA
ATTGCTTTATCCAGCAATGGAGGATAGGCGTCTTGATCTCACTGTGGGCAAGGGCAGTACCGCTCGCACCAGGGCATTGG
AGCTGCCTCCGTTCACTCTGGTGGGTGCTACGACTCGCGCTGGTGCCCTTAGCTCGCCGCTGCGGGATCGTTTCGGTCTT
ATTCAACGATTGGAGTTTTATGGCCTGGAGGATCTGCAAGCGATTGTTGAGCGGGCGGCTGGGCTGCTGAGGTTGCAGTT
AACTGCACAAGCCTGCCAGGAGATTGCTCGTCGCTGTAGGGGTACACCGAGGATCGCCAACAGATTGCTGCGACGGGTTC
GTGATGTAGCGAGTGTCTGTGGCGGGGAGAGCTTGATCGATGCTGCATTGGTGGATGAGGCTCTCACTTTGCATCGAGTC
GATGCTCGGGGTCTTGATGCCAGTGATCGGCGCTTGTTGGACTTGTTGCTGGAGTCTCATGGCGGTGGCCCGGTCGGTTT
GGAGACTTTGGCTGCCGCTTTGGGAGAGGATCCAGCCACTCTTGAAGCAGTGGTAGAACCATTTCTGCTGCAGCTGGGTT
TTTTGCAGCGAACTCCGCGTGGGCGCGTGGTGACTGGCGCGGGGCGACGCCATCTTGGTTGGCCGGAGTTGCCATGA

Upstream 100 bases:

>100_bases
AGAAGCCATCGCGGAGATTGGCTTGGCCGGCCCGGATTGACTTGACTTCGGTTCCCACCAACTCAATGCCAGTTTCAAGG
GTGTCGAGGATCTCGTATTG

Downstream 100 bases:

>100_bases
GCGTTCTCCAGGGGTTGAAAAACTGGGTGACTAGATGGTCAGGTTTGCTTTTAGTTGCGCTGTTGCTGGTCATGGATCCC
GTCACTGGAGCAGCTACCCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPCQTVVREQTVGRGSSSSSRFFVSSLGHLRLPMLSTLSRDRYSSNMAIVSSSAGRADSQPPAAKSRVVDASPLPEEASP
AREDGLRPKRLEDYIGQRELKQVLGIAVKAAMGRGDALDHVLLYGPPGLGKTTMAMVLAEELGVKCRVTSAPALERPRDI
VGLLVNLQPREVLFIDEIHRLTRVAEELLYPAMEDRRLDLTVGKGSTARTRALELPPFTLVGATTRAGALSSPLRDRFGL
IQRLEFYGLEDLQAIVERAAGLLRLQLTAQACQEIARRCRGTPRIANRLLRRVRDVASVCGGESLIDAALVDEALTLHRV
DARGLDASDRRLLDLLLESHGGGPVGLETLAAALGEDPATLEAVVEPFLLQLGFLQRTPRGRVVTGAGRRHLGWPELP

Sequences:

>Translated_398_residues
MPCQTVVREQTVGRGSSSSSRFFVSSLGHLRLPMLSTLSRDRYSSNMAIVSSSAGRADSQPPAAKSRVVDASPLPEEASP
AREDGLRPKRLEDYIGQRELKQVLGIAVKAAMGRGDALDHVLLYGPPGLGKTTMAMVLAEELGVKCRVTSAPALERPRDI
VGLLVNLQPREVLFIDEIHRLTRVAEELLYPAMEDRRLDLTVGKGSTARTRALELPPFTLVGATTRAGALSSPLRDRFGL
IQRLEFYGLEDLQAIVERAAGLLRLQLTAQACQEIARRCRGTPRIANRLLRRVRDVASVCGGESLIDAALVDEALTLHRV
DARGLDASDRRLLDLLLESHGGGPVGLETLAAALGEDPATLEAVVEPFLLQLGFLQRTPRGRVVTGAGRRHLGWPELP
>Mature_397_residues
PCQTVVREQTVGRGSSSSSRFFVSSLGHLRLPMLSTLSRDRYSSNMAIVSSSAGRADSQPPAAKSRVVDASPLPEEASPA
REDGLRPKRLEDYIGQRELKQVLGIAVKAAMGRGDALDHVLLYGPPGLGKTTMAMVLAEELGVKCRVTSAPALERPRDIV
GLLVNLQPREVLFIDEIHRLTRVAEELLYPAMEDRRLDLTVGKGSTARTRALELPPFTLVGATTRAGALSSPLRDRFGLI
QRLEFYGLEDLQAIVERAAGLLRLQLTAQACQEIARRCRGTPRIANRLLRRVRDVASVCGGESLIDAALVDEALTLHRVD
ARGLDASDRRLLDLLLESHGGGPVGLETLAAALGEDPATLEAVVEPFLLQLGFLQRTPRGRVVTGAGRRHLGWPELP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=329, Percent_Identity=54.7112462006079, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 43168; Mature: 43037

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCQTVVREQTVGRGSSSSSRFFVSSLGHLRLPMLSTLSRDRYSSNMAIVSSSAGRADSQ
CCCHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PPAAKSRVVDASPLPEEASPAREDGLRPKRLEDYIGQRELKQVLGIAVKAAMGRGDALDH
CCHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
VLLYGPPGLGKTTMAMVLAEELGVKCRVTSAPALERPRDIVGLLVNLQPREVLFIDEIHR
EEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
LTRVAEELLYPAMEDRRLDLTVGKGSTARTRALELPPFTLVGATTRAGALSSPLRDRFGL
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCEEEECCCCCCCHHCCHHHHHHHH
IQRLEFYGLEDLQAIVERAAGLLRLQLTAQACQEIARRCRGTPRIANRLLRRVRDVASVC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GGESLIDAALVDEALTLHRVDARGLDASDRRLLDLLLESHGGGPVGLETLAAALGEDPAT
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHH
LEAVVEPFLLQLGFLQRTPRGRVVTGAGRRHLGWPELP
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PCQTVVREQTVGRGSSSSSRFFVSSLGHLRLPMLSTLSRDRYSSNMAIVSSSAGRADSQ
CCHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PPAAKSRVVDASPLPEEASPAREDGLRPKRLEDYIGQRELKQVLGIAVKAAMGRGDALDH
CCHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
VLLYGPPGLGKTTMAMVLAEELGVKCRVTSAPALERPRDIVGLLVNLQPREVLFIDEIHR
EEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
LTRVAEELLYPAMEDRRLDLTVGKGSTARTRALELPPFTLVGATTRAGALSSPLRDRFGL
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCEEEECCCCCCCHHCCHHHHHHHH
IQRLEFYGLEDLQAIVERAAGLLRLQLTAQACQEIARRCRGTPRIANRLLRRVRDVASVC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GGESLIDAALVDEALTLHRVDARGLDASDRRLLDLLLESHGGGPVGLETLAAALGEDPAT
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHH
LEAVVEPFLLQLGFLQRTPRGRVVTGAGRRHLGWPELP
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA