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The map label for this gene is tatD [C]

Identifier: 124026592

GI number: 124026592

Start: 1549943

End: 1550734

Strand: Reverse

Name: tatD [C]

Synonym: NATL1_18871

Alternate gene names: 124026592

Gene position: 1550734-1549943 (Counterclockwise)

Preceding gene: 124026593

Following gene: 124026591

Centisome position: 83.16

GC content: 38.26

Gene sequence:

>792_bases
TTGAGCGATTCGAAAAGTTCGATAATTGATAGTCACTGCCATATCGTATTCTCTAACTTTAATGAGGATAGAGAAAAAGT
TGCAGAAAGGTGGAGATCACAAGGAGTTAAAGCTTTATTGCATGCTTGCGTAGAACCATCTGAAATCCCTGCTATTAAAT
CAATGGCTGATCAATTTCAGGAGTTGAGATATTCAGTAGGAGTTCATCCATTGGACGCCCATCATTGGGGACCTGAAACT
TTAAGTGTTTTAAAAAATGCAGCTCTTGATGACAGTCGAGTTGTTGCTATTGGAGAATTAGGACTAGATCTTTTCAAAGC
AGAGAACTTGAGTGAGCAGCTTTCAATTTTAATGCCGCAATTAAACTTGGCTTTTGAATTGAAGTTACCGGTCATTGTTC
ATTGCAGAGATGCCGCAAAAGAAATGTTAGAAGTTTTTGCTAAGCTTTCTGAGCATGGTTGCTGTCCAAAAGGAGTTATG
CATTGCTGGAGTGGCAATGTCAAAGAGATGAAAGAGTTTCTTGATCTTGGCTTTTACATTAGCTTCAGTGGAAATGTAAC
TTTCAAAAACGCTATTGATATCCATGAATGTGCTAAAAAAGTTCCTCAAAGTAGATTTTTAGTTGAAACCGATAGCCCTT
TCTTGTCACCTGTCCCTCATAGAGGCAAAAGGAATGAACCTTCTTTCGTAAAGCACGTGGTAGATAAAATTTCAGAGATT
AGAGGCGAAAGCTTTTCTGAAATTGCTGAAAAAAGCACTCAAAACGCAAGGGAATTGTTTGCGTTGCCTTAA

Upstream 100 bases:

>100_bases
AATCAGAAATCTCGACTTAGCGTTGCGCTTAAGAAGGTTTTGAAAGAAGTTGTTTGAGAATAAATAATCTAATATTGAAA
GAGAATTTCATTTTTCTATC

Downstream 100 bases:

>100_bases
ATATCATCATTTCCTCTAGTTAATTCTCTGGTTTGAGTGTAGAGTTATTTATTGTCTTGCCTAGGCGTGGTATCTACGCT
TAAACCTTAAGGTTCACCTT

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSDSKSSIIDSHCHIVFSNFNEDREKVAERWRSQGVKALLHACVEPSEIPAIKSMADQFQELRYSVGVHPLDAHHWGPET
LSVLKNAALDDSRVVAIGELGLDLFKAENLSEQLSILMPQLNLAFELKLPVIVHCRDAAKEMLEVFAKLSEHGCCPKGVM
HCWSGNVKEMKEFLDLGFYISFSGNVTFKNAIDIHECAKKVPQSRFLVETDSPFLSPVPHRGKRNEPSFVKHVVDKISEI
RGESFSEIAEKSTQNARELFALP

Sequences:

>Translated_263_residues
MSDSKSSIIDSHCHIVFSNFNEDREKVAERWRSQGVKALLHACVEPSEIPAIKSMADQFQELRYSVGVHPLDAHHWGPET
LSVLKNAALDDSRVVAIGELGLDLFKAENLSEQLSILMPQLNLAFELKLPVIVHCRDAAKEMLEVFAKLSEHGCCPKGVM
HCWSGNVKEMKEFLDLGFYISFSGNVTFKNAIDIHECAKKVPQSRFLVETDSPFLSPVPHRGKRNEPSFVKHVVDKISEI
RGESFSEIAEKSTQNARELFALP
>Mature_262_residues
SDSKSSIIDSHCHIVFSNFNEDREKVAERWRSQGVKALLHACVEPSEIPAIKSMADQFQELRYSVGVHPLDAHHWGPETL
SVLKNAALDDSRVVAIGELGLDLFKAENLSEQLSILMPQLNLAFELKLPVIVHCRDAAKEMLEVFAKLSEHGCCPKGVMH
CWSGNVKEMKEFLDLGFYISFSGNVTFKNAIDIHECAKKVPQSRFLVETDSPFLSPVPHRGKRNEPSFVKHVVDKISEIR
GESFSEIAEKSTQNARELFALP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI110349730, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI226061853, Length=280, Percent_Identity=27.8571428571429, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI226061614, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI225903424, Length=203, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI225903439, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI14042943, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226061595, Length=237, Percent_Identity=26.5822784810127, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=35.408560311284, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=30.6201550387597, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI48994985, Length=264, Percent_Identity=30.3030303030303, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=285, Percent_Identity=24.2105263157895, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=25.4752851711027, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=222, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648690, Length=289, Percent_Identity=28.719723183391, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221330018, Length=272, Percent_Identity=26.1029411764706, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586117, Length=272, Percent_Identity=26.1029411764706, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29513; Mature: 29382

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSKSSIIDSHCHIVFSNFNEDREKVAERWRSQGVKALLHACVEPSEIPAIKSMADQFQ
CCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ELRYSVGVHPLDAHHWGPETLSVLKNAALDDSRVVAIGELGLDLFKAENLSEQLSILMPQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHCHHHHHHCCHHHHHHHHHHC
LNLAFELKLPVIVHCRDAAKEMLEVFAKLSEHGCCPKGVMHCWSGNVKEMKEFLDLGFYI
CCEEEEECCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCEEE
SFSGNVTFKNAIDIHECAKKVPQSRFLVETDSPFLSPVPHRGKRNEPSFVKHVVDKISEI
EECCCEEECCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGESFSEIAEKSTQNARELFALP
CCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSKSSIIDSHCHIVFSNFNEDREKVAERWRSQGVKALLHACVEPSEIPAIKSMADQFQ
CCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ELRYSVGVHPLDAHHWGPETLSVLKNAALDDSRVVAIGELGLDLFKAENLSEQLSILMPQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHCHHHHHHCCHHHHHHHHHHC
LNLAFELKLPVIVHCRDAAKEMLEVFAKLSEHGCCPKGVMHCWSGNVKEMKEFLDLGFYI
CCEEEEECCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCEEE
SFSGNVTFKNAIDIHECAKKVPQSRFLVETDSPFLSPVPHRGKRNEPSFVKHVVDKISEI
EECCCEEECCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGESFSEIAEKSTQNARELFALP
CCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]