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The map label for this gene is rpoC1

Identifier: 124026590

GI number: 124026590

Start: 1544451

End: 1546358

Strand: Reverse

Name: rpoC1

Synonym: NATL1_18851

Alternate gene names: 124026590

Gene position: 1546358-1544451 (Counterclockwise)

Preceding gene: 124026591

Following gene: 124026589

Centisome position: 82.93

GC content: 38.63

Gene sequence:

>1908_bases
ATGACTAATAGCAATCTACGTACGGAAAATCATTTTGATTATGTAAAAATAAAATTAGCATCGCCTGAAAGAGTAATGGA
GTGGGGGCAAAGGACTTTGCCTAATGGTCAGGTTGTAGGGGAAGTAACTAAGCCAGAAACAATAAATTATCGAACACTCA
AGCCTGAAATGGATGGGTTGTTTTGTGAAAAGATTTTTGGTCCGTCCAAGGATTGGGAATGTCATTGTGGGAAATATAAG
AGGGTTAGACATCGTGGAATTGTTTGTGAGAGGTGTGGTGTTGAAGTAACAGAAAGTCGAGTTAGGAGACATAGAATGGG
ATTTATTAAATTAGCAGCTCCTGTATCACATGTTTGGTATCTAAAAGGTATTCCTAGCTATGTAGCTATTTTGTTAGATA
TGCCTCTTAGAGATGTTGAGCAAATCGTCTACTTTAATTGTTATGTGGTTTTAGATATTGGAGATAGTAAAGATTTAAAA
TATAAGCAGCTATTAACAGAAGATGAATGGCTTGAGATTGAAGACGAGATTTATGCCGAGGATTCAACTATTGAGAATGA
ACCCATCGTTGGCATAGGTGCAGAGGCCTTAAAACAATTACTTGAAGATTTAAATTTAAAAGAAGTTGCTGAGCAATTAC
GAGAAGATATTGCAACAAGTAAAGGTCAAAAAAGGGCTAAGCTTATAAAAAGACTAAGGGTAATAGATAACTTTATTGCT
ACAAGCGCAAGTCCAGAATGGATGGTTTTAGATGCGATACCTGTAATACCTCCTGATTTGAGGCCTATGGTGCAACTAGA
TGGAGGTAGATTCGCTACCTCAGATTTAAATGATTTATATAGAAGAGTAATCAATAGGAACAACCGTCTTGCTCGTCTTC
AGGAAATACTAGCTCCGGAAATAATAGTCAGAAATGAAAAAAGGATGCTGCAAGAGGCTGTAGATGCACTTATTGATAAT
GGTAGAAGAGGACGAACTGTTGTTGGCGCAAATAATCGCCCCTTGAAATCATTAAGCGATATTATCGAGGGTAAGCAAGG
TAGATTTAGACAGAATTTGCTTGGGAAAAGAGTTGATTATTCAGGTCGCTCGGTAATAGTAGTTGGCCCCAAGTTGAAAA
TGCATCAATGTGGATTGCCAAAGGAAATGGCGATAGAACTTTTTCAGCCTTTTGTAATTCATCGATTGATTCGCCAGAAC
ATTGTCAATAACATAAAAGCTGCAAAGAAATTGATACAGAAAGCAGACGATGAAGTAATGCAGGTATTACAGGAAGTCAT
AGAGGGTCATCCTATCCTGCTTAACCGTGCTCCTACTTTGCACCGATTAGGCATTCAAGCTTTTGAACCTAAATTAGTTG
CTGGACGAGCTATACAGCTACATCCATTAGTATGTCCAGCTTTTAATGCTGATTTTGATGGAGATCAAATGGCTGTTCAT
GTGCCTTTGGCAATTGAAGCGCAAACAGAAGCAAGGATGTTAATGCTAGCGAGTAACAATATTCTTTCCCCTGCAACTGG
GGATCCAATAGTTACCCCATCTCAAGATATGGTTTTAGGGTCTTACTACCTTACTGCAATTCAGCCTCAAGCAAAGCAGC
CAAAGTTCGGAGATTATTCAGATACCTATGCATCACTTGAAGATGTTTTACAAGCTCTTGAAGATAAAAGAATAGATTTA
CATGATTGGGTTTGGGTTCGATTTTCTGGTGAAATTGAGGATGACGATGAGCTTCAGAAACCGCTTAAGTCAGAGACTTT
GAAAGACGGTACCCGTATTGAGGAATGGACATATCGACGTGACCGATTAGATGAAGATGGAAGTTTAATTAGCCGTTATA
TATTGACTACTGTTGGCCGTGTCGTAATGAACCATACAATTATTGATGCCGTAGCAGCCACTTCGTAA

Upstream 100 bases:

>100_bases
TAGAAGCACGCCAAGTAGACCTACCTATGAATCATTAGGTAAAGAATACGAGGAGTAATCGATTCAATCTAAACAAATTA
TCTAAACACACTAAACTCTC

Downstream 100 bases:

>100_bases
ACCTTAGAACAAATCCACTTTTTTCTTGAATAGCATTTTATCATGACTTCCTCCTCTCCTAAAACTCGTAAATCCTCTAC
TAAATCAAAAGCAAAAAGAG

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MTNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLK
YKQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIA
TSASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQAKQPKFGDYSDTYASLEDVLQALEDKRIDL
HDWVWVRFSGEIEDDDELQKPLKSETLKDGTRIEEWTYRRDRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS

Sequences:

>Translated_635_residues
MTNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLK
YKQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIA
TSASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQAKQPKFGDYSDTYASLEDVLQALEDKRIDL
HDWVWVRFSGEIEDDDELQKPLKSETLKDGTRIEEWTYRRDRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS
>Mature_634_residues
TNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLKY
KQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIAT
SASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVHV
PLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQAKQPKFGDYSDTYASLEDVLQALEDKRIDLH
DWVWVRFSGEIEDDDELQKPLKSETLKDGTRIEEWTYRRDRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily

Homologues:

Organism=Homo sapiens, GI4505939, Length=510, Percent_Identity=27.0588235294118, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI39725938, Length=322, Percent_Identity=28.2608695652174, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=30.3571428571429, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI2367335, Length=516, Percent_Identity=61.6279069767442, Blast_Score=690, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=323, Percent_Identity=30.9597523219814, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=30.8196721311475, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71998295, Length=336, Percent_Identity=24.4047619047619, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320061, Length=518, Percent_Identity=26.8339768339768, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324690, Length=227, Percent_Identity=36.1233480176211, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17530899, Length=338, Percent_Identity=29.585798816568, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360912, Length=503, Percent_Identity=25.844930417495, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17647875, Length=337, Percent_Identity=28.1899109792285, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC1_PROM1 (A2C4N1)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015705.1
- ProteinModelPortal:   A2C4N1
- SMR:   A2C4N1
- STRING:   A2C4N1
- GeneID:   4780050
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_18851
- eggNOG:   COG0086
- HOGENOM:   HBG285548
- OMA:   HVWYLKG
- ProtClustDB:   PRK02625
- BioCyc:   PMAR167555:NATL1_18851-MONOMER
- HAMAP:   MF_01323
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755
- SMART:   SM00663
- TIGRFAMs:   TIGR02387

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3

EC number: =2.7.7.6

Molecular weight: Translated: 72252; Mature: 72121

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHCCCCCCEECCHHHCCC
DSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TSASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCHHHCCCEEEECCEECCCCCCCCCCCCEEEE
VPLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQAKQPKFGDYS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
DTYASLEDVLQALEDKRIDLHDWVWVRFSGEIEDDDELQKPLKSETLKDGTRIEEWTYRR
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
DRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKIKLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDIGDSKDLKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHCCCCCCEECCHHHCCC
DSTIENEPIVGIGAEALKQLLEDLNLKEVAEQLREDIATSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TSASPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCHHHCCCEEEECCEECCCCCCCCCCCCEEEE
VPLAIEAQTEARMLMLASNNILSPATGDPIVTPSQDMVLGSYYLTAIQPQAKQPKFGDYS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
DTYASLEDVLQALEDKRIDLHDWVWVRFSGEIEDDDELQKPLKSETLKDGTRIEEWTYRR
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
DRLDEDGSLISRYILTTVGRVVMNHTIIDAVAATS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA