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The map label for this gene is queF [H]

Identifier: 124026565

GI number: 124026565

Start: 1519743

End: 1520129

Strand: Reverse

Name: queF [H]

Synonym: NATL1_18601

Alternate gene names: 124026565

Gene position: 1520129-1519743 (Counterclockwise)

Preceding gene: 124026568

Following gene: 124026561

Centisome position: 81.52

GC content: 31.01

Gene sequence:

>387_bases
ATGTATGGGGAGAGGGAAATAGAGGCTGGGAGTTTAATTTGTTTCCCAAATCCAAATATTAATAGAGATTATGAGATTTC
AATAGATTTCCCTGAATTTACCTGTAAGTGTCCTTTTTCGGGATATCCTGATTTTGCAACTTTGAAAATTAAATATCAAC
CAAATACTAAGGTTATAGAATTAAAGGCAATTAAACTTTACTTAAATAGCTTTCGAGAAAAGAAGATATCTCATGAAGAA
GTTACGAATAAAATTATCGATGACTTTGTTGAAGTTTCTGATCCTAAGTGGATGCAATTAGAAGCTGATTTCAATCCTAG
AGGTAATGTTCATACAATCATTAGAGTCTGTCATGGGAAAAGAAAAAATTTAGATCTAATTCTCTAA

Upstream 100 bases:

>100_bases
TTATTTAAAGTTTGAATTTTTAATCAAGCTTTTATGTAGTGTGAGTTTTAAATGCAGTTAAAATGTGATTAGACAAGAAA
AAGACATCAAAGATGAAATT

Downstream 100 bases:

>100_bases
AAAACTAATAAGATTTGGCAATTCTTTTGAAAGACCAGAGAGATTTCTATTACTTAATCCACCTATATAAATCATAGATT
TTTCATTTTCATGTAAGACC

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MYGEREIEAGSLICFPNPNINRDYEISIDFPEFTCKCPFSGYPDFATLKIKYQPNTKVIELKAIKLYLNSFREKKISHEE
VTNKIIDDFVEVSDPKWMQLEADFNPRGNVHTIIRVCHGKRKNLDLIL

Sequences:

>Translated_128_residues
MYGEREIEAGSLICFPNPNINRDYEISIDFPEFTCKCPFSGYPDFATLKIKYQPNTKVIELKAIKLYLNSFREKKISHEE
VTNKIIDDFVEVSDPKWMQLEADFNPRGNVHTIIRVCHGKRKNLDLIL
>Mature_128_residues
MYGEREIEAGSLICFPNPNINRDYEISIDFPEFTCKCPFSGYPDFATLKIKYQPNTKVIELKAIKLYLNSFREKKISHEE
VTNKIIDDFVEVSDPKWMQLEADFNPRGNVHTIIRVCHGKRKNLDLIL

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 14955; Mature: 14955

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGEREIEAGSLICFPNPNINRDYEISIDFPEFTCKCPFSGYPDFATLKIKYQPNTKVIE
CCCCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEECCCCEEEE
LKAIKLYLNSFREKKISHEEVTNKIIDDFVEVSDPKWMQLEADFNPRGNVHTIIRVCHGK
EEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCC
RKNLDLIL
CCCCEEEC
>Mature Secondary Structure
MYGEREIEAGSLICFPNPNINRDYEISIDFPEFTCKCPFSGYPDFATLKIKYQPNTKVIE
CCCCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEECCCCEEEE
LKAIKLYLNSFREKKISHEEVTNKIIDDFVEVSDPKWMQLEADFNPRGNVHTIIRVCHGK
EEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCC
RKNLDLIL
CCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA