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The map label for this gene is atpB

Identifier: 124026559

GI number: 124026559

Start: 1514831

End: 1515556

Strand: Reverse

Name: atpB

Synonym: NATL1_18541

Alternate gene names: 124026559

Gene position: 1515556-1514831 (Counterclockwise)

Preceding gene: 124026560

Following gene: 124026558

Centisome position: 81.27

GC content: 40.36

Gene sequence:

>726_bases
ATGGGTTTTTTGCCATTTGTTTTTCCTTTCGCTGAATTAGAAGTTGGTCAACAACTTTATTGGCAAATTGGAAATTTTAG
AATTCACGGCCAAGTCTTTATGACTTCATGGCTTCTTATAGGCGCTTTGCTTGCCTTAGTAGTCATTGGGACTAAAAAAA
TGGAACGTGATCCAAGGGGTGTCCAGAACCTTTTGGAATTTCTTTGGGATTACATACGTGATCTTGCAAGAACACAAATT
GGTGAAAAGGTTTATAGAGATTGGATGCCTTTCATCGGAACCCTCTTTCTGTTCATTTTTGTGAGCAATTGGGGCGGTGC
ATTAGTTCCTTGGAAGCTGATCAAACTCCCAAGTGGTGAGCTTGGGGCACCTACAGCTGACATAAATACAACTGTTGCAT
TAGCACTACTGGTATCTCTCTCATATTTCTATGCGGGCTTGAGCAATAAAGGTTTGCGTTACTTCGAGTATTACGTTCAC
CCAACGCCAATTATGCTCCCATTCAAAATTGTAGAAGATTTTACAAAGCCTCTTTCTCTCTCTTTCCGTTTATTTGGAAA
CATTCTGGCTGATGAACTTGTTGTAGCGGTGCTCGTTTTTCTAGTACCTCTTGTTCTTCCAGTTCCAGTTATGTTTTTAG
GCTTGTTTACTAGTGCTATTCAAGCTCTGATTTTTGCAACTCTTGCTGCTTACTACATCGGGGAAGCAGTTGAAGAGCAT
CATTAA

Upstream 100 bases:

>100_bases
TATTCAGTTTCTATCTATGCCATAGGGCTTATTTAGAAATCAAATTTTTAAGTTTTGTTTGTTTGGCTTTTATTTTCTAC
GCAACCTAAACTTCCAGATA

Downstream 100 bases:

>100_bases
TCATAACTTTTTGCTATTGAATTAACTTTTTAATGGCAAATTTCCTGCTTTTAGGCCTGAAATTCTTTCAGTATCATCTC
AAGAACTATGAGATGCACCC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGFLPFVFPFAELEVGQQLYWQIGNFRIHGQVFMTSWLLIGALLALVVIGTKKMERDPRGVQNLLEFLWDYIRDLARTQI
GEKVYRDWMPFIGTLFLFIFVSNWGGALVPWKLIKLPSGELGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVH
PTPIMLPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H

Sequences:

>Translated_241_residues
MGFLPFVFPFAELEVGQQLYWQIGNFRIHGQVFMTSWLLIGALLALVVIGTKKMERDPRGVQNLLEFLWDYIRDLARTQI
GEKVYRDWMPFIGTLFLFIFVSNWGGALVPWKLIKLPSGELGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVH
PTPIMLPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H
>Mature_240_residues
GFLPFVFPFAELEVGQQLYWQIGNFRIHGQVFMTSWLLIGALLALVVIGTKKMERDPRGVQNLLEFLWDYIRDLARTQIG
EKVYRDWMPFIGTLFLFIFVSNWGGALVPWKLIKLPSGELGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVHP
TPIMLPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_PROM1 (A2C4K0)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015674.1
- ProteinModelPortal:   A2C4K0
- STRING:   A2C4K0
- GeneID:   4780466
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_18541
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- BioCyc:   PMAR167555:NATL1_18541-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27259; Mature: 27127

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x203bfea8)-; HASH(0x2235e58c)-; HASH(0x21b53ea4)-; HASH(0x217cfaac)-; HASH(0x21be0850)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLPFVFPFAELEVGQQLYWQIGNFRIHGQVFMTSWLLIGALLALVVIGTKKMERDPRG
CCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFIFVSNWGGALVPWKLIKLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCC
LGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVHPTPIMLPFKIVEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHH
SFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
H
H
>Mature Secondary Structure 
GFLPFVFPFAELEVGQQLYWQIGNFRIHGQVFMTSWLLIGALLALVVIGTKKMERDPRG
CCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFIFVSNWGGALVPWKLIKLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCC
LGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVHPTPIMLPFKIVEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHH
SFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
H
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA