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The map label for this gene is fabZ [H]

Identifier: 124026468

GI number: 124026468

Start: 1443771

End: 1444178

Strand: Reverse

Name: fabZ [H]

Synonym: NATL1_17631

Alternate gene names: 124026468

Gene position: 1444178-1443771 (Counterclockwise)

Preceding gene: 124026469

Following gene: 124026467

Centisome position: 77.45

GC content: 41.18

Gene sequence:

>408_bases
ATGGGGCTTTTGCCACATAGATATCCCTTTGCGCTTGTTGACAGAGTGATAGAACATGATCAAGGCAAGAAAGCTGTGGC
AATAAAAAATGTCACTCTTAATGAGCCGCAATTTCAAGGCCATTTTCCTGATAGACCACTAATGCCTGGAGTTTTAATAG
TAGAAGCAATGGCTCAAGTCGGTGGTTTGATTGTTTCTCAAATGCCTGATCTTCCAAAAGGGCTTTTTGTGTTCGCTGGG
ATTGATTCGGTTCGGTTTAGGCGTCCAGTGGTTCCAGGAGATCAATTATTGATATCTTGTGAGTTGATAAGCATCAAAAG
AAAGAGATTTGGGAAAGTTAAGGGAGAAGCAAAAGTGGATGATCAGTTGGTTTGTTCTGGAGATTTGATGTTCTCTCTTG
TGGATTGA

Upstream 100 bases:

>100_bases
TGAATTTGCAGCTTCTCTTCAAAAAGTATTAACTTAATTAAATCTGATTTTGACTGAAATTTCTCCTTCCCAACCTCTTG
TTTTAAATAGCGAGCAAATA

Downstream 100 bases:

>100_bases
AGTAATGATTGAACGTCAATCTTCTAAAAGCTTAATTGCAGATAACAAAGTAAATATTCATGAATTTGCGGACGTCTCTC
CAAAAGCTGAACTTGGCAGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MGLLPHRYPFALVDRVIEHDQGKKAVAIKNVTLNEPQFQGHFPDRPLMPGVLIVEAMAQVGGLIVSQMPDLPKGLFVFAG
IDSVRFRRPVVPGDQLLISCELISIKRKRFGKVKGEAKVDDQLVCSGDLMFSLVD

Sequences:

>Translated_135_residues
MGLLPHRYPFALVDRVIEHDQGKKAVAIKNVTLNEPQFQGHFPDRPLMPGVLIVEAMAQVGGLIVSQMPDLPKGLFVFAG
IDSVRFRRPVVPGDQLLISCELISIKRKRFGKVKGEAKVDDQLVCSGDLMFSLVD
>Mature_134_residues
GLLPHRYPFALVDRVIEHDQGKKAVAIKNVTLNEPQFQGHFPDRPLMPGVLIVEAMAQVGGLIVSQMPDLPKGLFVFAGI
DSVRFRRPVVPGDQLLISCELISIKRKRFGKVKGEAKVDDQLVCSGDLMFSLVD

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=130, Percent_Identity=50, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 14923; Mature: 14792

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLPHRYPFALVDRVIEHDQGKKAVAIKNVTLNEPQFQGHFPDRPLMPGVLIVEAMAQV
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GGLIVSQMPDLPKGLFVFAGIDSVRFRRPVVPGDQLLISCELISIKRKRFGKVKGEAKVD
HHHHHHCCCCCCCCEEEEECCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCC
DQLVCSGDLMFSLVD
CEEEECCCEEEEECC
>Mature Secondary Structure 
GLLPHRYPFALVDRVIEHDQGKKAVAIKNVTLNEPQFQGHFPDRPLMPGVLIVEAMAQV
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GGLIVSQMPDLPKGLFVFAGIDSVRFRRPVVPGDQLLISCELISIKRKRFGKVKGEAKVD
HHHHHHCCCCCCCCEEEEECCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCC
DQLVCSGDLMFSLVD
CEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]