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The map label for this gene is argD [H]

Identifier: 124026426

GI number: 124026426

Start: 1406116

End: 1407378

Strand: Direct

Name: argD [H]

Synonym: NATL1_17211

Alternate gene names: 124026426

Gene position: 1406116-1407378 (Clockwise)

Preceding gene: 124026425

Following gene: 124026427

Centisome position: 75.41

GC content: 38.24

Gene sequence:

>1263_bases
GTGGAATTGGTAGACGCACCGCACTCAAAATGCGGCACCTTCGGGTTTGTCGGTTCAAGTCCGACCGCTCCCACTTCATT
GATGAAAACTTACAATCGTTTTCCCTTAGATCTTATTAGGGGTAAAGGCTCATGGGTGTGGGATAAAAAAGGCCGAAAAT
ATCTTGATGCTGTGGCTGGAATTGCAACATGTTCACTAGGCCACAGTGATAAAGCATTAATCAAATCCTTATCAAAACAA
TTAAAAAGACTTCAACACGTATCTAACCTTTACGGAATACCAGAGCAAGAAGAATTAGCTCAATGGTTAACTTCAAAAAG
TTTTGCCAAGAGTGTATTTTTTTGCAATAGCGGTGCTGAAGCAAACGAAGCTGCAATTAAATTGGCAAGAAAATATGGGC
ATATTGAACGTAATATCGACAACCCAGTCATTCTTTGCTCAAAGGAAAGCTTTCACGGAAGAACACTCGCCGCTGTAAGT
GCGACAGGCCAAACGAAATACCACAAAGGTTTCGAGCCAATGGTTCAGGGATTTCAGTTTTTTTCTTATAATGACAGTGA
ATCTTTTGAAAATCTATTTGATACTTTAGAAAAAACAGGTCCACAAATTGCAGCTGTATTTATTGAACCTATACAAGGTG
AGGGAGGAATAAATATTGGAAAAAAATCATTTTTTGAGCTCTTAAGAAAAAAATGTACTCACAGCAATGTTTTATTGATA
TTTGACGAAGTCCAAACTGGAATGGGGAGGACAGGTACTCTTTGGGGATATGAACAACTAGGTATTGAACCTGATGTTTT
CACACTAGCCAAAGGGCTTGGTGGAGGTCATGCAATTGGAGCGCTATTAGTTAATCAATTAGCTGATGTCTTTCAGCCCG
GTGATCATGCCAGCACTTTTGGAGGGAATCCTTTCGCATGCAGAGCAGCTCTAACCGTTGGACAAGAAATACAAAAAAGA
GACCTACTAAATAAAGTCACTGAGAGAGGTGCTCAATTAAAAGAAGGATTAATTAAACTTTCAAATAAATATTCAGACAT
ATTTATTTCCACTAGAGGCGTTGGGCTTATTCAAGGTCTCGTTCTAAAAGACAATATCAAAACAACATCTCTTGATATTG
TCAAATTCGCCTTAGAAGAGAAACTACTTTTAGTATCTGCTGGTGTAAAAGTATTAAGGATAGTCCCTCCTCTGACTATT
ACAAAAAAAGAAATCAACGAGCTTTTATCGAGACTAGACAAATGTCTGATGAAACTTTCTTAG

Upstream 100 bases:

>100_bases
TAACAAAATAATTAGTGAAGACAATATTGATACTCAAAAAAATGCAGCTTAGTTTCATATATTTGCTAGTTTTGACATAA
AATAAACACATGGGAGCGTG

Downstream 100 bases:

>100_bases
CACAATCGAATTTCATTTCTGAAAGCAAGAGCAAAGAATATAAAGATATGAATCTGGGCATAGATCGTATGTCATTGGCT
ATTAATGCTATGGGAGATCC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MELVDAPHSKCGTFGFVGSSPTAPTSLMKTYNRFPLDLIRGKGSWVWDKKGRKYLDAVAGIATCSLGHSDKALIKSLSKQ
LKRLQHVSNLYGIPEQEELAQWLTSKSFAKSVFFCNSGAEANEAAIKLARKYGHIERNIDNPVILCSKESFHGRTLAAVS
ATGQTKYHKGFEPMVQGFQFFSYNDSESFENLFDTLEKTGPQIAAVFIEPIQGEGGINIGKKSFFELLRKKCTHSNVLLI
FDEVQTGMGRTGTLWGYEQLGIEPDVFTLAKGLGGGHAIGALLVNQLADVFQPGDHASTFGGNPFACRAALTVGQEIQKR
DLLNKVTERGAQLKEGLIKLSNKYSDIFISTRGVGLIQGLVLKDNIKTTSLDIVKFALEEKLLLVSAGVKVLRIVPPLTI
TKKEINELLSRLDKCLMKLS

Sequences:

>Translated_420_residues
MELVDAPHSKCGTFGFVGSSPTAPTSLMKTYNRFPLDLIRGKGSWVWDKKGRKYLDAVAGIATCSLGHSDKALIKSLSKQ
LKRLQHVSNLYGIPEQEELAQWLTSKSFAKSVFFCNSGAEANEAAIKLARKYGHIERNIDNPVILCSKESFHGRTLAAVS
ATGQTKYHKGFEPMVQGFQFFSYNDSESFENLFDTLEKTGPQIAAVFIEPIQGEGGINIGKKSFFELLRKKCTHSNVLLI
FDEVQTGMGRTGTLWGYEQLGIEPDVFTLAKGLGGGHAIGALLVNQLADVFQPGDHASTFGGNPFACRAALTVGQEIQKR
DLLNKVTERGAQLKEGLIKLSNKYSDIFISTRGVGLIQGLVLKDNIKTTSLDIVKFALEEKLLLVSAGVKVLRIVPPLTI
TKKEINELLSRLDKCLMKLS
>Mature_420_residues
MELVDAPHSKCGTFGFVGSSPTAPTSLMKTYNRFPLDLIRGKGSWVWDKKGRKYLDAVAGIATCSLGHSDKALIKSLSKQ
LKRLQHVSNLYGIPEQEELAQWLTSKSFAKSVFFCNSGAEANEAAIKLARKYGHIERNIDNPVILCSKESFHGRTLAAVS
ATGQTKYHKGFEPMVQGFQFFSYNDSESFENLFDTLEKTGPQIAAVFIEPIQGEGGINIGKKSFFELLRKKCTHSNVLLI
FDEVQTGMGRTGTLWGYEQLGIEPDVFTLAKGLGGGHAIGALLVNQLADVFQPGDHASTFGGNPFACRAALTVGQEIQKR
DLLNKVTERGAQLKEGLIKLSNKYSDIFISTRGVGLIQGLVLKDNIKTTSLDIVKFALEEKLLLVSAGVKVLRIVPPLTI
TKKEINELLSRLDKCLMKLS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=394, Percent_Identity=30.9644670050761, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI284507298, Length=306, Percent_Identity=32.3529411764706, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=30.3448275862069, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=26.6666666666667, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=26.1904761904762, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=24.1050119331742, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=26.7352185089974, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=26.0143198090692, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=26.0143198090692, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=26.0143198090692, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=39.7932816537468, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=37.17277486911, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI145693181, Length=389, Percent_Identity=31.8766066838046, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=32.6781326781327, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=31.3924050632911, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786991, Length=417, Percent_Identity=25.6594724220624, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786349, Length=350, Percent_Identity=26.5714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=31.331592689295, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI32564660, Length=430, Percent_Identity=29.5348837209302, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=268, Percent_Identity=32.089552238806, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=27.6346604215457, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=442, Percent_Identity=28.5067873303167, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71981843, Length=157, Percent_Identity=31.8471337579618, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=36.5671641791045, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.3333333333333, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6321456, Length=432, Percent_Identity=29.1666666666667, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324386, Length=450, Percent_Identity=22.8888888888889, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=31.4720812182741, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI28574759, Length=413, Percent_Identity=30.0242130750605, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=28.7383177570093, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=26.3657957244656, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=436, Percent_Identity=27.0642201834862, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667139, Length=436, Percent_Identity=27.0642201834862, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667143, Length=436, Percent_Identity=27.0642201834862, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 46061; Mature: 46061

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVDAPHSKCGTFGFVGSSPTAPTSLMKTYNRFPLDLIRGKGSWVWDKKGRKYLDAVAG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHEECCCCEEECCCCHHHHHHHHH
IATCSLGHSDKALIKSLSKQLKRLQHVSNLYGIPEQEELAQWLTSKSFAKSVFFCNSGAE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCC
ANEAAIKLARKYGHIERNIDNPVILCSKESFHGRTLAAVSATGQTKYHKGFEPMVQGFQF
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
FSYNDSESFENLFDTLEKTGPQIAAVFIEPIQGEGGINIGKKSFFELLRKKCTHSNVLLI
CCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
FDEVQTGMGRTGTLWGYEQLGIEPDVFTLAKGLGGGHAIGALLVNQLADVFQPGDHASTF
EECHHCCCCCCCCCCCHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GGNPFACRAALTVGQEIQKRDLLNKVTERGAQLKEGLIKLSNKYSDIFISTRGVGLIQGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCE
VLKDNIKTTSLDIVKFALEEKLLLVSAGVKVLRIVPPLTITKKEINELLSRLDKCLMKLS
EEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELVDAPHSKCGTFGFVGSSPTAPTSLMKTYNRFPLDLIRGKGSWVWDKKGRKYLDAVAG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHEECCCCEEECCCCHHHHHHHHH
IATCSLGHSDKALIKSLSKQLKRLQHVSNLYGIPEQEELAQWLTSKSFAKSVFFCNSGAE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCC
ANEAAIKLARKYGHIERNIDNPVILCSKESFHGRTLAAVSATGQTKYHKGFEPMVQGFQF
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
FSYNDSESFENLFDTLEKTGPQIAAVFIEPIQGEGGINIGKKSFFELLRKKCTHSNVLLI
CCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
FDEVQTGMGRTGTLWGYEQLGIEPDVFTLAKGLGGGHAIGALLVNQLADVFQPGDHASTF
EECHHCCCCCCCCCCCHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GGNPFACRAALTVGQEIQKRDLLNKVTERGAQLKEGLIKLSNKYSDIFISTRGVGLIQGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCE
VLKDNIKTTSLDIVKFALEEKLLLVSAGVKVLRIVPPLTITKKEINELLSRLDKCLMKLS
EEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]