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The map label for this gene is fbp [H]

Identifier: 124026418

GI number: 124026418

Start: 1399739

End: 1400293

Strand: Direct

Name: fbp [H]

Synonym: NATL1_17131

Alternate gene names: 124026418

Gene position: 1399739-1400293 (Clockwise)

Preceding gene: 124026416

Following gene: 124026419

Centisome position: 75.06

GC content: 42.34

Gene sequence:

>555_bases
ATGATTGCAGTGATTAGCCAAATCATCTCACCGACTCCAACGAATGCCTTACAAATTGACCAACCAATCCAAGCGGATGT
AAGGCAATCCACAAAAACCAGCGAGTCTGTAACTAATCCATTTGAATTAGACCCAGAAGACCCAAATCCATCACTTTTTA
CTATGGCTTCAGATAAAACCAGTGCAAGCAACGCTCCTCTCGGAGGCGCTGAGATAGGGGCATCTCAAGTAACTTCAAGT
GGGCTAAAAATTACTGAATTAGTTTTAGGTGATGGTCAAGAAGCTACCCCAGGAACAAGTGTCTCAGTAAATTACAAGGG
TACTCTTGATGATGGGAAAGAATTTGACAGCAGTTATGGGAGAGGTCCTTTTGAATTTTCGTTAGGTGCAGGAATGGTGA
TAAAAGGTTGGGATGAGGGAGTCGCAGGAATGAAAGTTGGAGGTAAAAGAAAATTAGTCATTCCACCAGAATTGGGGTAT
GGCAGCAGAGGAATAGGTCCAATCCCTCCTAATTCAGTGTTAACGTTTGAAGTGGAATTATTAGCTGTTAAGTGA

Upstream 100 bases:

>100_bases
TAGATGTAATTTGGGTATTAATCTGCAAGAATATTTTCGAGTACTTAATATTACTGTGAGAGAAATCTTAATTAGCTTTT
CTGTTTGCCTTAGCTGCTTG

Downstream 100 bases:

>100_bases
GTTTCTTAAATTATTCAGAAAGCTCTAGATAAAGTTATGGCGTTTGTTGACAAACGCCATTAATGTAAAAAAAAATGTTC
ACAAATTATTCTCAGATGTT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIAVISQIISPTPTNALQIDQPIQADVRQSTKTSESVTNPFELDPEDPNPSLFTMASDKTSASNAPLGGAEIGASQVTSS
GLKITELVLGDGQEATPGTSVSVNYKGTLDDGKEFDSSYGRGPFEFSLGAGMVIKGWDEGVAGMKVGGKRKLVIPPELGY
GSRGIGPIPPNSVLTFEVELLAVK

Sequences:

>Translated_184_residues
MIAVISQIISPTPTNALQIDQPIQADVRQSTKTSESVTNPFELDPEDPNPSLFTMASDKTSASNAPLGGAEIGASQVTSS
GLKITELVLGDGQEATPGTSVSVNYKGTLDDGKEFDSSYGRGPFEFSLGAGMVIKGWDEGVAGMKVGGKRKLVIPPELGY
GSRGIGPIPPNSVLTFEVELLAVK
>Mature_184_residues
MIAVISQIISPTPTNALQIDQPIQADVRQSTKTSESVTNPFELDPEDPNPSLFTMASDKTSASNAPLGGAEIGASQVTSS
GLKITELVLGDGQEATPGTSVSVNYKGTLDDGKEFDSSYGRGPFEFSLGAGMVIKGWDEGVAGMKVGGKRKLVIPPELGY
GSRGIGPIPPNSVLTFEVELLAVK

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=93, Percent_Identity=55.9139784946236, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI17149844, Length=93, Percent_Identity=55.9139784946236, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI17149842, Length=93, Percent_Identity=55.9139784946236, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI224809329, Length=107, Percent_Identity=55.1401869158878, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI224809327, Length=107, Percent_Identity=55.1401869158878, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI4758384, Length=107, Percent_Identity=55.1401869158878, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI224809331, Length=107, Percent_Identity=55.1401869158878, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI17149836, Length=107, Percent_Identity=46.7289719626168, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI4503725, Length=107, Percent_Identity=46.7289719626168, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=47.2527472527472, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758380, Length=107, Percent_Identity=43.9252336448598, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI4503729, Length=89, Percent_Identity=51.685393258427, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI33469985, Length=85, Percent_Identity=47.0588235294118, Blast_Score=81, Evalue=4e-16,
Organism=Homo sapiens, GI192448443, Length=93, Percent_Identity=47.3118279569892, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4503727, Length=114, Percent_Identity=40.3508771929825, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=40.5660377358491, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI7706131, Length=87, Percent_Identity=39.0804597701149, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI206725547, Length=94, Percent_Identity=43.6170212765958, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI31317231, Length=95, Percent_Identity=43.1578947368421, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=54.5454545454545, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI87082390, Length=110, Percent_Identity=49.0909090909091, Blast_Score=81, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=54.8387096774194, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71993519, Length=88, Percent_Identity=57.9545454545455, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17561778, Length=112, Percent_Identity=45.5357142857143, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=103, Percent_Identity=47.5728155339806, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323566, Length=110, Percent_Identity=47.2727272727273, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320727, Length=94, Percent_Identity=59.5744680851064, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323482, Length=110, Percent_Identity=47.2727272727273, Blast_Score=101, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6324194, Length=113, Percent_Identity=47.787610619469, Blast_Score=94, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647110, Length=110, Percent_Identity=55.4545454545455, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281363946, Length=94, Percent_Identity=56.3829787234042, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17352457, Length=94, Percent_Identity=56.3829787234042, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=53.2710280373832, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21356629, Length=95, Percent_Identity=55.7894736842105, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24583150, Length=89, Percent_Identity=52.8089887640449, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19154; Mature: 19154

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVISQIISPTPTNALQIDQPIQADVRQSTKTSESVTNPFELDPEDPNPSLFTMASDKT
CHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEECCCC
SASNAPLGGAEIGASQVTSSGLKITELVLGDGQEATPGTSVSVNYKGTLDDGKEFDSSYG
CCCCCCCCCHHCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHCC
RGPFEFSLGAGMVIKGWDEGVAGMKVGGKRKLVIPPELGYGSRGIGPIPPNSVLTFEVEL
CCCEEEECCCCEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEE
LAVK
EEEC
>Mature Secondary Structure
MIAVISQIISPTPTNALQIDQPIQADVRQSTKTSESVTNPFELDPEDPNPSLFTMASDKT
CHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEECCCC
SASNAPLGGAEIGASQVTSSGLKITELVLGDGQEATPGTSVSVNYKGTLDDGKEFDSSYG
CCCCCCCCCHHCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHCC
RGPFEFSLGAGMVIKGWDEGVAGMKVGGKRKLVIPPELGYGSRGIGPIPPNSVLTFEVEL
CCCEEEECCCCEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEE
LAVK
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]