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The map label for this gene is ppnK [H]

Identifier: 124026393

GI number: 124026393

Start: 1375970

End: 1376878

Strand: Reverse

Name: ppnK [H]

Synonym: NATL1_16881

Alternate gene names: 124026393

Gene position: 1376878-1375970 (Counterclockwise)

Preceding gene: 124026394

Following gene: 124026391

Centisome position: 73.84

GC content: 41.14

Gene sequence:

>909_bases
GTGCCCCGAGTAGGACTGATCGTTAATGACGGGAAAGAGCTTGCTGTTAAGACAGCAAAAACTTTTCAAAAAAAACTAGA
AGATTCTGGTTTTGAGGTCGTAAGAGTAAGTAGCGCAGGCGGTTTATTAGGTTTTACTAATCCTGATCAATACATGAGTT
CACAAGGATACAACTCATGTATTCCAGATGGTTTTGATTCTTCAATTTTGTTTGCCGTTGTATTGGGAGGCGATGGGACT
GTCTTGTCTGCAGCAAGACAAACTGCACCATTGGGTATCCCCATACTCACTGTAAATACAGGACATTTAGGCTTTTTGGC
TGAGGCGTATCTTTCAGATATAGATAAAATTTTCAAACATTTAGTTGCAAGGCAATGGAGTATTGAGAAAAGAACAAGCC
TAGTAGTGAGTGTTATGAGAGGTGATCAATGTAGATGGGAAGCTCTTTGCCTCAATGAAATGGCATTGCATAGAGAACCT
ATGACAAGTATGTGTCATTTTGAAATTTCTGTTGGTCGGCATGCGCCCGTCGATATTTCTGCAGATGGTGTAATTCTCTC
TACTCCTACTGGTTCAACTGCTTATTCACTCAGTGCCGGGGGACCTGTCATTACTCCTGATTGTCCAGTTCTACAGCTTA
CGCCTGTATCTCCTCATTCATTAGCATCCAGAGCTCTTGTTTTTAGCAACGAAGAGCCAGTAACGGTTTTTCCTGCCACA
CCTGAAAGATTAATGATGGTAGTTGATGGTAGTGCAGGCTGTTATGTATGGCCAGAGGATAGAGTTTTAATCAGAAAAAG
TGATCATCCAGTTAAGTTCATTAGACTTTCCGATCATGAGTTCTTTCAAGTTCTAAGAAATAAATTAGGTTGGGGACTCC
CCCACGTTGCGAAACCTGATAAAACATAA

Upstream 100 bases:

>100_bases
ATTTTAAAGTTGGATTTTTTGAATTAAATTTTAATTTATTAAATAAATAATATTGACATTTAATTGCTAATATTGTGCAA
TAGTTTGTGAAGTATGATCG

Downstream 100 bases:

>100_bases
AAATTATTTAATTTCACCTTTCAAAATAAAAACAGGATTTAAAGGAGATAATCTTATATCTTCTCCAATACTTACACCTC
TATACGATTGATGTTGACTA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MPRVGLIVNDGKELAVKTAKTFQKKLEDSGFEVVRVSSAGGLLGFTNPDQYMSSQGYNSCIPDGFDSSILFAVVLGGDGT
VLSAARQTAPLGIPILTVNTGHLGFLAEAYLSDIDKIFKHLVARQWSIEKRTSLVVSVMRGDQCRWEALCLNEMALHREP
MTSMCHFEISVGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPVSPHSLASRALVFSNEEPVTVFPAT
PERLMMVVDGSAGCYVWPEDRVLIRKSDHPVKFIRLSDHEFFQVLRNKLGWGLPHVAKPDKT

Sequences:

>Translated_302_residues
MPRVGLIVNDGKELAVKTAKTFQKKLEDSGFEVVRVSSAGGLLGFTNPDQYMSSQGYNSCIPDGFDSSILFAVVLGGDGT
VLSAARQTAPLGIPILTVNTGHLGFLAEAYLSDIDKIFKHLVARQWSIEKRTSLVVSVMRGDQCRWEALCLNEMALHREP
MTSMCHFEISVGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPVSPHSLASRALVFSNEEPVTVFPAT
PERLMMVVDGSAGCYVWPEDRVLIRKSDHPVKFIRLSDHEFFQVLRNKLGWGLPHVAKPDKT
>Mature_301_residues
PRVGLIVNDGKELAVKTAKTFQKKLEDSGFEVVRVSSAGGLLGFTNPDQYMSSQGYNSCIPDGFDSSILFAVVLGGDGTV
LSAARQTAPLGIPILTVNTGHLGFLAEAYLSDIDKIFKHLVARQWSIEKRTSLVVSVMRGDQCRWEALCLNEMALHREPM
TSMCHFEISVGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPVSPHSLASRALVFSNEEPVTVFPATP
ERLMMVVDGSAGCYVWPEDRVLIRKSDHPVKFIRLSDHEFFQVLRNKLGWGLPHVAKPDKT

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788968, Length=222, Percent_Identity=34.6846846846847, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=30.6772908366534, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325068, Length=158, Percent_Identity=34.1772151898734, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322509, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573828, Length=256, Percent_Identity=27.734375, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573830, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573832, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161077047, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573826, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129957, Length=281, Percent_Identity=25.6227758007117, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32819; Mature: 32688

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVGLIVNDGKELAVKTAKTFQKKLEDSGFEVVRVSSAGGLLGFTNPDQYMSSQGYNSC
CCCEEEEEECCCCEEHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHCCCCCCC
IPDGFDSSILFAVVLGGDGTVLSAARQTAPLGIPILTVNTGHLGFLAEAYLSDIDKIFKH
CCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
LVARQWSIEKRTSLVVSVMRGDQCRWEALCLNEMALHREPMTSMCHFEISVGRHAPVDIS
HHHHCCCCHHHHHHEEHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEC
ADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPVSPHSLASRALVFSNEEPVTVFPAT
CCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCHHHHHCEEEEECCCCCEEEECCC
PERLMMVVDGSAGCYVWPEDRVLIRKSDHPVKFIRLSDHEFFQVLRNKLGWGLPHVAKPD
CCCEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
KT
CC
>Mature Secondary Structure 
PRVGLIVNDGKELAVKTAKTFQKKLEDSGFEVVRVSSAGGLLGFTNPDQYMSSQGYNSC
CCEEEEEECCCCEEHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHCCCCCCC
IPDGFDSSILFAVVLGGDGTVLSAARQTAPLGIPILTVNTGHLGFLAEAYLSDIDKIFKH
CCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
LVARQWSIEKRTSLVVSVMRGDQCRWEALCLNEMALHREPMTSMCHFEISVGRHAPVDIS
HHHHCCCCHHHHHHEEHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEC
ADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPVSPHSLASRALVFSNEEPVTVFPAT
CCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCHHHHHCEEEEECCCCCEEEECCC
PERLMMVVDGSAGCYVWPEDRVLIRKSDHPVKFIRLSDHEFFQVLRNKLGWGLPHVAKPD
CCCEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
KT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA