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The map label for this gene is phrA [H]

Identifier: 124026272

GI number: 124026272

Start: 1271884

End: 1272999

Strand: Direct

Name: phrA [H]

Synonym: NATL1_15661

Alternate gene names: 124026272

Gene position: 1271884-1272999 (Clockwise)

Preceding gene: 124026271

Following gene: 124026273

Centisome position: 68.21

GC content: 29.57

Gene sequence:

>1116_bases
ATGAATATTTTTGATGAGGCTAATGATTTATTAGATAATTTCATTTTCAATCACCTTAATTCATACCATCAACTAAGAAA
TTACGATTATGGGATCGAAGATAGGACTAATGTTTCTCAGATTTCTAAATATACATCACATAGAATTCTCTACGAATTTG
ACATAATTGAAAAATTAAAAAAGTATGATAAGAAACAAAAGTACACTGATGAAATCCTTTGGAGAATCTATTGGAAGGGT
TACCTTGAAAATTACAAATCTATATGGTTTGAATATATAAATTTCAAAGAAAACTCAAATAATTCATACTTAATTAGTTC
TGCGATAAATGGTAAGACAGGTATAGATTGCTTTGATACATGGATAGAGGAGCTTAGAGAGAATAACTATTTGCATAATC
ACGCAAGGATGTGGTTCGCAAGTATATGGATTTTCACTCTGGGACTTCCATGGCAATTAGGAGCGAGGCTTTTTATGAAA
CATCTGCTAGATGGGGATGCTGCATCAAACACCCTTAGCTGGAGATGGGTGGCTGGAATGCACACTAATAAGAAGCCTTA
CTTAGCATCTAAAGAAAACATCAACAAGTACACAGTTAATCGATTTAGAGATACATCAATTAGCCTCTCGAGCAAAATTA
ATATCATAAAACATAGTCAACATAAATCGAATAAACTTCCAGTTCAAAGAAGTTTTCCTAATAGTAATATTCTAATAATG
TTTGATAATGATATGGATATCATGAGCAGATCTACGTTATTTAATTCATACTCAAAAGTTTATATATTGCGTAATATAGC
CATAAATAATGAATTTGATCTAAGTGAGAACGTGAGTCAATTCAAACGAGGTTTAATTGATAAAGTAAATAAGTTAATTC
CAAACTCAGAAGTATTAAAATCAACTGACCTAGGAATTAATTTGTCTGGTCACAATTTTATTGATGTTATCTACCCAGGA
GTTGGTCATAATCTAGATTTAATAAATAAATTCGCCAATCAAAATCAAATCATTTTTAATTATATATATAGAGAAGATGA
CCTTAAATATTGGAATTATGCAAATTCAGGATTTTACAAATTTAAGACTTCATTTAATAGAATTAATATGATCTAA

Upstream 100 bases:

>100_bases
GTAATAAAACATATATTTGAAGACCTTCTAAATGGTCCAGCTCATATAAAAGAAGCTATAAAAGCATTAAAAAAACTTCA
ATAATAAATTTAATACTCTT

Downstream 100 bases:

>100_bases
AATCTTATTAATTTTATTAAATCAATACAAACAGATCATCCAGGTCTACCACACTTAAATTAAATCATAATTATAGTAAA
TAAACATTTTCAAAGGGTTA

Product: DNA photolyase-like protein

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNIFDEANDLLDNFIFNHLNSYHQLRNYDYGIEDRTNVSQISKYTSHRILYEFDIIEKLKKYDKKQKYTDEILWRIYWKG
YLENYKSIWFEYINFKENSNNSYLISSAINGKTGIDCFDTWIEELRENNYLHNHARMWFASIWIFTLGLPWQLGARLFMK
HLLDGDAASNTLSWRWVAGMHTNKKPYLASKENINKYTVNRFRDTSISLSSKINIIKHSQHKSNKLPVQRSFPNSNILIM
FDNDMDIMSRSTLFNSYSKVYILRNIAINNEFDLSENVSQFKRGLIDKVNKLIPNSEVLKSTDLGINLSGHNFIDVIYPG
VGHNLDLINKFANQNQIIFNYIYREDDLKYWNYANSGFYKFKTSFNRINMI

Sequences:

>Translated_371_residues
MNIFDEANDLLDNFIFNHLNSYHQLRNYDYGIEDRTNVSQISKYTSHRILYEFDIIEKLKKYDKKQKYTDEILWRIYWKG
YLENYKSIWFEYINFKENSNNSYLISSAINGKTGIDCFDTWIEELRENNYLHNHARMWFASIWIFTLGLPWQLGARLFMK
HLLDGDAASNTLSWRWVAGMHTNKKPYLASKENINKYTVNRFRDTSISLSSKINIIKHSQHKSNKLPVQRSFPNSNILIM
FDNDMDIMSRSTLFNSYSKVYILRNIAINNEFDLSENVSQFKRGLIDKVNKLIPNSEVLKSTDLGINLSGHNFIDVIYPG
VGHNLDLINKFANQNQIIFNYIYREDDLKYWNYANSGFYKFKTSFNRINMI
>Mature_371_residues
MNIFDEANDLLDNFIFNHLNSYHQLRNYDYGIEDRTNVSQISKYTSHRILYEFDIIEKLKKYDKKQKYTDEILWRIYWKG
YLENYKSIWFEYINFKENSNNSYLISSAINGKTGIDCFDTWIEELRENNYLHNHARMWFASIWIFTLGLPWQLGARLFMK
HLLDGDAASNTLSWRWVAGMHTNKKPYLASKENINKYTVNRFRDTSISLSSKINIIKHSQHKSNKLPVQRSFPNSNILIM
FDNDMDIMSRSTLFNSYSKVYILRNIAINNEFDLSENVSQFKRGLIDKVNKLIPNSEVLKSTDLGINLSGHNFIDVIYPG
VGHNLDLINKFANQNQIIFNYIYREDDLKYWNYANSGFYKFKTSFNRINMI

Specific function: Involved in repair of UV radiation-induced DNA damage. Exhibits specific, light-dependent repair activity for a cyclobutyl pyrimidine dimer by catalyzing the light-dependent monomerization (300-600 nm) of the dimers (in cis-syn configuration), which are f

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=189, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324962, Length=138, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR019947
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 44109; Mature: 44109

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFDEANDLLDNFIFNHLNSYHQLRNYDYGIEDRTNVSQISKYTSHRILYEFDIIEKLK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCEEEEEHHHHHHHH
KYDKKQKYTDEILWRIYWKGYLENYKSIWFEYINFKENSNNSYLISSAINGKTGIDCFDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCHHHHH
WIEELRENNYLHNHARMWFASIWIFTLGLPWQLGARLFMKHLLDGDAASNTLSWRWVAGM
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
HTNKKPYLASKENINKYTVNRFRDTSISLSSKINIIKHSQHKSNKLPVQRSFPNSNILIM
CCCCCCCCCCCCCCCHHHHHHHCCCCEEHHHCEEEEECCCCCCCCCCCEECCCCCCEEEE
FDNDMDIMSRSTLFNSYSKVYILRNIAINNEFDLSENVSQFKRGLIDKVNKLIPNSEVLK
ECCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
STDLGINLSGHNFIDVIYPGVGHNLDLINKFANQNQIIFNYIYREDDLKYWNYANSGFYK
HCCCEEEECCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCCEEE
FKTSFNRINMI
EEECCCCCCCC
>Mature Secondary Structure
MNIFDEANDLLDNFIFNHLNSYHQLRNYDYGIEDRTNVSQISKYTSHRILYEFDIIEKLK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCEEEEEHHHHHHHH
KYDKKQKYTDEILWRIYWKGYLENYKSIWFEYINFKENSNNSYLISSAINGKTGIDCFDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCHHHHH
WIEELRENNYLHNHARMWFASIWIFTLGLPWQLGARLFMKHLLDGDAASNTLSWRWVAGM
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
HTNKKPYLASKENINKYTVNRFRDTSISLSSKINIIKHSQHKSNKLPVQRSFPNSNILIM
CCCCCCCCCCCCCCCHHHHHHHCCCCEEHHHCEEEEECCCCCCCCCCCEECCCCCCEEEE
FDNDMDIMSRSTLFNSYSKVYILRNIAINNEFDLSENVSQFKRGLIDKVNKLIPNSEVLK
ECCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
STDLGINLSGHNFIDVIYPGVGHNLDLINKFANQNQIIFNYIYREDDLKYWNYANSGFYK
HCCCEEEECCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCCEEE
FKTSFNRINMI
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11254140; 8905231; 10896222; 10871367 [H]