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The map label for this gene is coaD

Identifier: 124025706

GI number: 124025706

Start: 920519

End: 920995

Strand: Reverse

Name: coaD

Synonym: NATL1_09991

Alternate gene names: 124025706

Gene position: 920995-920519 (Counterclockwise)

Preceding gene: 124025711

Following gene: 124025701

Centisome position: 49.39

GC content: 36.9

Gene sequence:

>477_bases
ATGAAGGCGCTTTATCCGGGTAGTTTCGACCCATTAACGTTTGGGCACCTTGATCTAATTCAACGAGGAAGTGATTTATT
TGGGGAGGTTCTCATTGCAGTATTAGAAAACCCCTCAAAAAAGGCAACTTTCTCCTGCAAGAGAAGAATCGAGCAGATTG
AAAATGCTACTAAAGATATCCCAGGTTGCAGAACAATAGCTTTTAAAGGATTAACTGTTGATTGTGCTCGTGAAAACAAT
GCTGATCTTATTTTAAGAGGCTTAAGAGCTATGAGTGATTTTGAATATGAACTACAAGTTGCTCATACAAACAGATCTTT
AAATAATCAGTACGAAACAATTTTTCTCGCGACAGAAACGCACCATAGCTTTTTAAGTAGTTCAGTAGTTAAAGAAGTCG
CAAGATTTGGCGGTGAGATTCGCCATATGGTTCCTGAATTTATTGCTAAGGATCTTATGAAACTAAATACTAATTAA

Upstream 100 bases:

>100_bases
AAGAACTTTTTTTGCATCCTGATTGAGAGTCATGCGCTTTGATACGTTTAAACATATGTGATTCTATGAAAGAAATGGAC
ATTTTTAAAACTAAAACACA

Downstream 100 bases:

>100_bases
GTACAATAATTAGTATTATCTACTATTGATAAAATATTAATAATATTCTTCGTCGAATTTTCCTTATTATTAACAATAAT
ACTAAATATTTTATCTTTAC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDIPGCRTIAFKGLTVDCARENN
ADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATETHHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN

Sequences:

>Translated_158_residues
MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDIPGCRTIAFKGLTVDCARENN
ADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATETHHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN
>Mature_158_residues
MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDIPGCRTIAFKGLTVDCARENN
ADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATETHHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=152, Percent_Identity=42.1052631578947, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PROM1 (A2C247)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014822.1
- ProteinModelPortal:   A2C247
- SMR:   A2C247
- STRING:   A2C247
- GeneID:   4780529
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09991
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   PMAR167555:NATL1_09991-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17807; Mature: 17807

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDI
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
PGCRTIAFKGLTVDCARENNADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATET
CCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECH
HHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDI
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
PGCRTIAFKGLTVDCARENNADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATET
CCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECH
HHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA