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The map label for this gene is purN [H]

Identifier: 124025699

GI number: 124025699

Start: 911298

End: 911996

Strand: Reverse

Name: purN [H]

Synonym: NATL1_09921

Alternate gene names: 124025699

Gene position: 911996-911298 (Counterclockwise)

Preceding gene: 124025701

Following gene: 124025697

Centisome position: 48.91

GC content: 29.47

Gene sequence:

>699_bases
ATGAATCAAAATAATAAAGAATATTGCGAAAGTAACTTATTTAATGGTTTAAATGGACGGAGCCTAATAAGTCCAAATGA
ATCAGTCAGTAATTTTATTGAGCCAAAGATTAGATTAGGTATCCTTGCATCTGGAAATGGATCAAATTTTGAATTCATTA
TTAAATCTATTCAAAACAATGAACTTAATGCAGAAGTATCTATATTAATTGTTAATAATCCTAATTGCTTAGCAATAGAA
AAGGCAATTAAATATGATATACCCTATGTAATTATTAATCATAGAGATTGTAATTCGAGATTAGAACACGATAAATTGGT
TATGAATAAACTAGAGGAACTATCTGTAGAACTAGTTGTCATGGCTGGGTGGATGAGAATTGTTGGTGAAGAAATAATTA
ATAAGTTCAATAATAGACTAATTAATATACATCCATCACTTTTACCATCTTTTAAAGGCATTGATGCAATACAGCAGGCA
ATGGACAAAAGGGTAACTATAACTGGCTGTACAGTTCACTATGTTCAAAAGGAGGTTGATTCAGGCTCAATAATTATTCA
AGCGGCAGTCCCTCTTAAAGAAAAAGATAGTATAGAAACCTTAAAAAAAAGAATTCAAGATATGGAACATATAATATTAC
CTTTAGCGATTGCTAAAGTAGCAATTGAAATTAGAACTAGTTTCAAGGATAAAAAGTAA

Upstream 100 bases:

>100_bases
ATACTAATCTAGAATATTATTAATATTAAAAATGTCTTTACATATAGATATTGTAATTTCATCGTTAGGTCGTATATTTG
TTGTATATAAGCCTTAATTG

Downstream 100 bases:

>100_bases
TCTTAGGAAGACCAATATCTGATTCAAGTCCGTGCATAATATTTAAATTTTGGACTGCCTGTCCTGCTTGACCTTTTAGA
AGATTATCTATAACACTCAT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNQNNKEYCESNLFNGLNGRSLISPNESVSNFIEPKIRLGILASGNGSNFEFIIKSIQNNELNAEVSILIVNNPNCLAIE
KAIKYDIPYVIINHRDCNSRLEHDKLVMNKLEELSVELVVMAGWMRIVGEEIINKFNNRLINIHPSLLPSFKGIDAIQQA
MDKRVTITGCTVHYVQKEVDSGSIIIQAAVPLKEKDSIETLKKRIQDMEHIILPLAIAKVAIEIRTSFKDKK

Sequences:

>Translated_232_residues
MNQNNKEYCESNLFNGLNGRSLISPNESVSNFIEPKIRLGILASGNGSNFEFIIKSIQNNELNAEVSILIVNNPNCLAIE
KAIKYDIPYVIINHRDCNSRLEHDKLVMNKLEELSVELVVMAGWMRIVGEEIINKFNNRLINIHPSLLPSFKGIDAIQQA
MDKRVTITGCTVHYVQKEVDSGSIIIQAAVPLKEKDSIETLKKRIQDMEHIILPLAIAKVAIEIRTSFKDKK
>Mature_232_residues
MNQNNKEYCESNLFNGLNGRSLISPNESVSNFIEPKIRLGILASGNGSNFEFIIKSIQNNELNAEVSILIVNNPNCLAIE
KAIKYDIPYVIINHRDCNSRLEHDKLVMNKLEELSVELVVMAGWMRIVGEEIINKFNNRLINIHPSLLPSFKGIDAIQQA
MDKRVTITGCTVHYVQKEVDSGSIIIQAAVPLKEKDSIETLKKRIQDMEHIILPLAIAKVAIEIRTSFKDKK

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=213, Percent_Identity=40.8450704225352, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI209869995, Length=213, Percent_Identity=40.8450704225352, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI209869993, Length=213, Percent_Identity=40.8450704225352, Blast_Score=175, Evalue=3e-44,
Organism=Escherichia coli, GI1788846, Length=181, Percent_Identity=33.7016574585635, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787483, Length=159, Percent_Identity=31.4465408805031, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17567511, Length=189, Percent_Identity=37.5661375661376, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320616, Length=206, Percent_Identity=26.6990291262136, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582400, Length=183, Percent_Identity=36.6120218579235, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 26182; Mature: 26182

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQNNKEYCESNLFNGLNGRSLISPNESVSNFIEPKIRLGILASGNGSNFEFIIKSIQNN
CCCCCHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCC
ELNAEVSILIVNNPNCLAIEKAIKYDIPYVIINHRDCNSRLEHDKLVMNKLEELSVELVV
CCCCEEEEEEEECCCEEEEHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
MAGWMRIVGEEIINKFNNRLINIHPSLLPSFKGIDAIQQAMDKRVTITGCTVHYVQKEVD
HHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCHHHHHHHHHCEEEEEEHHHEEHHHHCC
SGSIIIQAAVPLKEKDSIETLKKRIQDMEHIILPLAIAKVAIEIRTSFKDKK
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQNNKEYCESNLFNGLNGRSLISPNESVSNFIEPKIRLGILASGNGSNFEFIIKSIQNN
CCCCCHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCC
ELNAEVSILIVNNPNCLAIEKAIKYDIPYVIINHRDCNSRLEHDKLVMNKLEELSVELVV
CCCCEEEEEEEECCCEEEEHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
MAGWMRIVGEEIINKFNNRLINIHPSLLPSFKGIDAIQQAMDKRVTITGCTVHYVQKEVD
HHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCHHHHHHHHHCEEEEEEHHHEEHHHHCC
SGSIIIQAAVPLKEKDSIETLKKRIQDMEHIILPLAIAKVAIEIRTSFKDKK
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA