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The map label for this gene is htpG [H]

Identifier: 124025686

GI number: 124025686

Start: 896312

End: 898216

Strand: Reverse

Name: htpG [H]

Synonym: NATL1_09791

Alternate gene names: 124025686

Gene position: 898216-896312 (Counterclockwise)

Preceding gene: 124025687

Following gene: 124025685

Centisome position: 48.17

GC content: 32.23

Gene sequence:

>1905_bases
ATGTCCGTTAAAGAAGAAGGAACTATTCTTATTCACACAGAAAATATATTTCCAATAATAAAAAAAGCAGTTTACTCAGA
TCATGAGATATTTATTAGAGAGCTTATAAGTAATTCCGTAGATGCAATCAAGAAAAGGAAAATGGCCGCCTTTGCAGGAG
ATTGTGTCGCTGCTGACGATGAAAAAATAAAAATTTCGATAGACAGAGAGCATAAGACATTGACCATTAGTGACAATGGA
ATAGGAATGACTAGTGATGAAATTAAGAAATATATTAATCAAGTAGCTTTCTCAAGTGCAGAAGAATTTCTTGAAAAATA
TAAGCAACCTGACGATGGTTTTATAGGCCATTTTGGACTCGGTTTTTACTCAAGTTTTATGGTTGCAGAAGAAGTTGAAA
TAATAACTAAATCAGCAAAGAATGACTCACAAGCTATTCAATGGAAATGCAATGGATCGCCTCAATATTCACTTGATGAA
TCAGATAAAGAAGAGGTAGGTACAGATATAATTTTACATTTAATGGAAGATGAAATTGAATATATAGAACCAAGCAGAAT
TAAGACATTAATTAAAAAATATTGTGATTTCATGCCTATTGAAATCTCACTTGAAGAAGAAGTTATCAATAAAATGAATC
CACCATGGAGAGAAAGCAAACAAAATCTTAAAGATGAAGATTATATTGAACTCTATAAATATCTCTATCCCTTTCAGGGA
GATCCTCTCTTATGGGTTCACCTAAATACTGACTATCCATATAATTTGCAAGGAATATTATATTTTCCAAAGATAAGTGG
AAGAGCAGATTGGGAAAGTGGTGAAATAAAACTTTTCTGTAATCAGGTCTTTGTTAGTGACTCAATTAAAGAGATAGTTC
CTAGATATCTTTTACCGTTGAGGGGTGTGATAGATTCACCAGACATTCCCTTAAATGTTAGTAGAAGCGCATTACAATCA
GACAGAAGAGTTAAATCTATAGGTAACTTTATTGCTAAGAAATTAGCCGATAAGCTTAAAACATTAAAGAAGGATGAAAC
CCAATTTTATGCTGACATATGGGACTCAATAGCCCCTTTTATAAAAATTGGAGCTATGGAAGATGAGAAATTTGCCGAGC
AAGTAAAAGATATAATTTTATATTCAACAACAAAAGTTCCTGTTGAAGATAATGAAGAGAATAACGAGTTGGTAAAATCT
GGTTCAAAAACATTTACTACCCTAGAAGGATATAAGAATAGGCTTACTGATGAGAACAAAAAGATTTTATATTCAACAGA
TGAAGTCTCTCAATCAACAGCACTAAATATGTGGACTTCACAAGGTAAAGAGGTCTTAAAACTTGATACTGTTATTGATA
CTCAGTTTATTCCTTGGCTAGAGGAAAAAAATAAAGAAATAAATTTTGTAAGAGTCGATTCCGAACTGGACGAAAATATT
AAAGATGATTCGCCTGAGATTGCAGATAAAGACGGGAATACAAAGTCAGAAACACTTAAAAAAATTATTAGTTCGGCTTT
AAACAATGAAAAAGTCACAGTACAAATACAGAATCTAAAAGGTGATAATTCACCACCTTCATTAATATTGTTACCAGAAC
AAATGAGAAGAATAAATGATATAACAGCATTAATGGAACAGAAACTGCCTGGTCTTCCTGAATATCATAATTTAATAGTC
AATTCAAACCACCCACTTATTCAAGGCTTACTCAAGCTAAATTCTAACCAAATAGTTATTGAAGGATCCAGTAAATCAGA
AGAAGGTCAATTAGCTAGCGACATCGCTATACATGTTTATGAGATGGCAAAACTATCAATTGGAGGGCTTGAGAACAAAG
ATATAGCAGCTTTTCAAAATAGAAATGCTGAGCTGCTAGGGAAATTAATGAAAAATTTCGTATAA

Upstream 100 bases:

>100_bases
TCAGGGATTGAAAACTATTGAGCTGTAATCAATAACACTTTTGCATTTAACGCCTAAATAGAAATTTGTATCGCTATGAT
AATAAAAATTTAGACAAGAC

Downstream 100 bases:

>100_bases
ACTCAACCTCATTTGATAGAATAAATAAACGAATAAGATTAAAAAATGTCTAGAGTTTGCCAACTTACAGGCACAAGGGC
TAATAACGGAATGTCAGTCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSVKEEGTILIHTENIFPIIKKAVYSDHEIFIRELISNSVDAIKKRKMAAFAGDCVAADDEKIKISIDREHKTLTISDNG
IGMTSDEIKKYINQVAFSSAEEFLEKYKQPDDGFIGHFGLGFYSSFMVAEEVEIITKSAKNDSQAIQWKCNGSPQYSLDE
SDKEEVGTDIILHLMEDEIEYIEPSRIKTLIKKYCDFMPIEISLEEEVINKMNPPWRESKQNLKDEDYIELYKYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPKISGRADWESGEIKLFCNQVFVSDSIKEIVPRYLLPLRGVIDSPDIPLNVSRSALQS
DRRVKSIGNFIAKKLADKLKTLKKDETQFYADIWDSIAPFIKIGAMEDEKFAEQVKDIILYSTTKVPVEDNEENNELVKS
GSKTFTTLEGYKNRLTDENKKILYSTDEVSQSTALNMWTSQGKEVLKLDTVIDTQFIPWLEEKNKEINFVRVDSELDENI
KDDSPEIADKDGNTKSETLKKIISSALNNEKVTVQIQNLKGDNSPPSLILLPEQMRRINDITALMEQKLPGLPEYHNLIV
NSNHPLIQGLLKLNSNQIVIEGSSKSEEGQLASDIAIHVYEMAKLSIGGLENKDIAAFQNRNAELLGKLMKNFV

Sequences:

>Translated_634_residues
MSVKEEGTILIHTENIFPIIKKAVYSDHEIFIRELISNSVDAIKKRKMAAFAGDCVAADDEKIKISIDREHKTLTISDNG
IGMTSDEIKKYINQVAFSSAEEFLEKYKQPDDGFIGHFGLGFYSSFMVAEEVEIITKSAKNDSQAIQWKCNGSPQYSLDE
SDKEEVGTDIILHLMEDEIEYIEPSRIKTLIKKYCDFMPIEISLEEEVINKMNPPWRESKQNLKDEDYIELYKYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPKISGRADWESGEIKLFCNQVFVSDSIKEIVPRYLLPLRGVIDSPDIPLNVSRSALQS
DRRVKSIGNFIAKKLADKLKTLKKDETQFYADIWDSIAPFIKIGAMEDEKFAEQVKDIILYSTTKVPVEDNEENNELVKS
GSKTFTTLEGYKNRLTDENKKILYSTDEVSQSTALNMWTSQGKEVLKLDTVIDTQFIPWLEEKNKEINFVRVDSELDENI
KDDSPEIADKDGNTKSETLKKIISSALNNEKVTVQIQNLKGDNSPPSLILLPEQMRRINDITALMEQKLPGLPEYHNLIV
NSNHPLIQGLLKLNSNQIVIEGSSKSEEGQLASDIAIHVYEMAKLSIGGLENKDIAAFQNRNAELLGKLMKNFV
>Mature_633_residues
SVKEEGTILIHTENIFPIIKKAVYSDHEIFIRELISNSVDAIKKRKMAAFAGDCVAADDEKIKISIDREHKTLTISDNGI
GMTSDEIKKYINQVAFSSAEEFLEKYKQPDDGFIGHFGLGFYSSFMVAEEVEIITKSAKNDSQAIQWKCNGSPQYSLDES
DKEEVGTDIILHLMEDEIEYIEPSRIKTLIKKYCDFMPIEISLEEEVINKMNPPWRESKQNLKDEDYIELYKYLYPFQGD
PLLWVHLNTDYPYNLQGILYFPKISGRADWESGEIKLFCNQVFVSDSIKEIVPRYLLPLRGVIDSPDIPLNVSRSALQSD
RRVKSIGNFIAKKLADKLKTLKKDETQFYADIWDSIAPFIKIGAMEDEKFAEQVKDIILYSTTKVPVEDNEENNELVKSG
SKTFTTLEGYKNRLTDENKKILYSTDEVSQSTALNMWTSQGKEVLKLDTVIDTQFIPWLEEKNKEINFVRVDSELDENIK
DDSPEIADKDGNTKSETLKKIISSALNNEKVTVQIQNLKGDNSPPSLILLPEQMRRINDITALMEQKLPGLPEYHNLIVN
SNHPLIQGLLKLNSNQIVIEGSSKSEEGQLASDIAIHVYEMAKLSIGGLENKDIAAFQNRNAELLGKLMKNFV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=645, Percent_Identity=26.3565891472868, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI4507677, Length=699, Percent_Identity=25.6080114449213, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI153792590, Length=197, Percent_Identity=36.5482233502538, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI154146191, Length=197, Percent_Identity=36.5482233502538, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI20149594, Length=199, Percent_Identity=36.1809045226131, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI1786679, Length=473, Percent_Identity=32.3467230443975, Blast_Score=249, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI115535205, Length=654, Percent_Identity=28.1345565749235, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI115535167, Length=427, Percent_Identity=31.3817330210773, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17559162, Length=663, Percent_Identity=26.395173453997, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17542208, Length=686, Percent_Identity=27.2594752186589, Blast_Score=196, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323840, Length=535, Percent_Identity=29.5327102803738, Blast_Score=193, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6325016, Length=203, Percent_Identity=38.423645320197, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24586016, Length=525, Percent_Identity=27.6190476190476, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI21357739, Length=689, Percent_Identity=26.5602322206096, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17647529, Length=419, Percent_Identity=26.0143198090692, Blast_Score=125, Evalue=9e-29,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72204; Mature: 72073

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKEEGTILIHTENIFPIIKKAVYSDHEIFIRELISNSVDAIKKRKMAAFAGDCVAADD
CCCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
EKIKISIDREHKTLTISDNGIGMTSDEIKKYINQVAFSSAEEFLEKYKQPDDGFIGHFGL
CEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHH
GFYSSFMVAEEVEIITKSAKNDSQAIQWKCNGSPQYSLDESDKEEVGTDIILHLMEDEIE
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YIEPSRIKTLIKKYCDFMPIEISLEEEVINKMNPPWRESKQNLKDEDYIELYKYLYPFQG
HCCHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPKISGRADWESGEIKLFCNQVFVSDSIKEIVPRYLLPL
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQSDRRVKSIGNFIAKKLADKLKTLKKDETQFYADIWDSIAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKIGAMEDEKFAEQVKDIILYSTTKVPVEDNEENNELVKSGSKTFTTLEGYKNRLTDENK
HEECCCCHHHHHHHHHHHHHEECEECCCCCCCCCHHHHHCCCCCEEEHHHHHHHCCCCCC
KILYSTDEVSQSTALNMWTSQGKEVLKLDTVIDTQFIPWLEEKNKEINFVRVDSELDENI
EEEEECCHHCHHHHHHHHHHCCCCEEEEHHHHCCHHCCCHHCCCCCEEEEEECCHHCCCC
KDDSPEIADKDGNTKSETLKKIISSALNNEKVTVQIQNLKGDNSPPSLILLPEQMRRIND
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECHHHHHHHHH
ITALMEQKLPGLPEYHNLIVNSNHPLIQGLLKLNSNQIVIEGSSKSEEGQLASDIAIHVY
HHHHHHHHCCCCCCHHCEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
EMAKLSIGGLENKDIAAFQNRNAELLGKLMKNFV
HHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SVKEEGTILIHTENIFPIIKKAVYSDHEIFIRELISNSVDAIKKRKMAAFAGDCVAADD
CCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
EKIKISIDREHKTLTISDNGIGMTSDEIKKYINQVAFSSAEEFLEKYKQPDDGFIGHFGL
CEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHH
GFYSSFMVAEEVEIITKSAKNDSQAIQWKCNGSPQYSLDESDKEEVGTDIILHLMEDEIE
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YIEPSRIKTLIKKYCDFMPIEISLEEEVINKMNPPWRESKQNLKDEDYIELYKYLYPFQG
HCCHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPKISGRADWESGEIKLFCNQVFVSDSIKEIVPRYLLPL
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQSDRRVKSIGNFIAKKLADKLKTLKKDETQFYADIWDSIAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKIGAMEDEKFAEQVKDIILYSTTKVPVEDNEENNELVKSGSKTFTTLEGYKNRLTDENK
HEECCCCHHHHHHHHHHHHHEECEECCCCCCCCCHHHHHCCCCCEEEHHHHHHHCCCCCC
KILYSTDEVSQSTALNMWTSQGKEVLKLDTVIDTQFIPWLEEKNKEINFVRVDSELDENI
EEEEECCHHCHHHHHHHHHHCCCCEEEEHHHHCCHHCCCHHCCCCCEEEEEECCHHCCCC
KDDSPEIADKDGNTKSETLKKIISSALNNEKVTVQIQNLKGDNSPPSLILLPEQMRRIND
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECHHHHHHHHH
ITALMEQKLPGLPEYHNLIVNSNHPLIQGLLKLNSNQIVIEGSSKSEEGQLASDIAIHVY
HHHHHHHHCCCCCCHHCEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
EMAKLSIGGLENKDIAAFQNRNAELLGKLMKNFV
HHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]