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The map label for this gene is ntcA [H]

Identifier: 124025037

GI number: 124025037

Start: 301052

End: 301783

Strand: Direct

Name: ntcA [H]

Synonym: NATL1_03241

Alternate gene names: 124025037

Gene position: 301052-301783 (Clockwise)

Preceding gene: 124025033

Following gene: 124025038

Centisome position: 16.14

GC content: 38.25

Gene sequence:

>732_bases
ATGGTCACTTCATATCGTGGCTTTACTCGTTTCAACCAACCCAAAAATAGCCAGATGGTTGGTAACTCCTCAACTCCATT
GCCGCCAAATAAAACTCTCTTAGATGTAATTAAATCTTTGGAGGGAGTTTCTACTGAAACTGTAGATAGATCAAAAACTA
TTTTTTTTCCTGGTGATCCTGCCGAAAGGGTTTATTTGATAAGACGTGGTGCAGTTCGATTGAGCAGAGTCTATGAAACG
GGTGAAGAAATTACTGTTGCTTTGTTGAGAGAAAATAGTCTGTTTGGAGTTTTATCTTTATTGACAGGTCATAGATCAGA
TCGTTTTTATCACGCTGTTGCCTTTACACGTGTGGAACTCGTTTCTGCTCCAGCCACTTCATTAAGGAATGCAATAGAGC
AAGATGCCTCTGTTGGGTTGCTCCTTTTACAAGGTTTATCAAGTCGAGTACTTCAAACTGAAACAATGATTGAAACTTTA
ACTCATAGAGATATGTCTTCTCGTCTCGCAAGTTTTTTACTTGTTTTGTGTAGAGACTTTGGTGTGCCTGGGGAAAAAGG
AGTCACAATTGACTTAAGACTCTCTCATCAAGCTATTGCTGAAGCAATAGGTTCAACCAGAGTTACTATTACACGACTAC
TTGGTGAGTTGAAAAGTTCCTCATTATTGGCAATAGATAGGAAGAAAATAACCATATTCGATCCAATAGCGTTAGCAAAA
AGATTTAATTGA

Upstream 100 bases:

>100_bases
GAGAACAGCCTTGGATTATTGACTTAGCTTCAAAAAAGTCGCCATGGCTACATATCGTTTTTTCTTGACTTATTAATGTT
CTTTGAACAATTAATTAAAT

Downstream 100 bases:

>100_bases
AGGCCATTGCATACTAAGGTTTAGGGGGTTTGATTAATTCTTCTTCTTTATCTCTGTGACTGCTTGGCTTAAAATTCTTT
TAGTATTAATCCTAGGTGGA

Product: CRP family global nitrogen regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MVTSYRGFTRFNQPKNSQMVGNSSTPLPPNKTLLDVIKSLEGVSTETVDRSKTIFFPGDPAERVYLIRRGAVRLSRVYET
GEEITVALLRENSLFGVLSLLTGHRSDRFYHAVAFTRVELVSAPATSLRNAIEQDASVGLLLLQGLSSRVLQTETMIETL
THRDMSSRLASFLLVLCRDFGVPGEKGVTIDLRLSHQAIAEAIGSTRVTITRLLGELKSSSLLAIDRKKITIFDPIALAK
RFN

Sequences:

>Translated_243_residues
MVTSYRGFTRFNQPKNSQMVGNSSTPLPPNKTLLDVIKSLEGVSTETVDRSKTIFFPGDPAERVYLIRRGAVRLSRVYET
GEEITVALLRENSLFGVLSLLTGHRSDRFYHAVAFTRVELVSAPATSLRNAIEQDASVGLLLLQGLSSRVLQTETMIETL
THRDMSSRLASFLLVLCRDFGVPGEKGVTIDLRLSHQAIAEAIGSTRVTITRLLGELKSSSLLAIDRKKITIFDPIALAK
RFN
>Mature_243_residues
MVTSYRGFTRFNQPKNSQMVGNSSTPLPPNKTLLDVIKSLEGVSTETVDRSKTIFFPGDPAERVYLIRRGAVRLSRVYET
GEEITVALLRENSLFGVLSLLTGHRSDRFYHAVAFTRVELVSAPATSLRNAIEQDASVGLLLLQGLSSRVLQTETMIETL
THRDMSSRLASFLLVLCRDFGVPGEKGVTIDLRLSHQAIAEAIGSTRVTITRLLGELKSSSLLAIDRKKITIFDPIALAK
RFN

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=193, Percent_Identity=26.9430051813472, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26864; Mature: 26864

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSYRGFTRFNQPKNSQMVGNSSTPLPPNKTLLDVIKSLEGVSTETVDRSKTIFFPGDP
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
AERVYLIRRGAVRLSRVYETGEEITVALLRENSLFGVLSLLTGHRSDRFYHAVAFTRVEL
HHHEEEEHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
VSAPATSLRNAIEQDASVGLLLLQGLSSRVLQTETMIETLTHRDMSSRLASFLLVLCRDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GVPGEKGVTIDLRLSHQAIAEAIGSTRVTITRLLGELKSSSLLAIDRKKITIFDPIALAK
CCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHH
RFN
CCC
>Mature Secondary Structure
MVTSYRGFTRFNQPKNSQMVGNSSTPLPPNKTLLDVIKSLEGVSTETVDRSKTIFFPGDP
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
AERVYLIRRGAVRLSRVYETGEEITVALLRENSLFGVLSLLTGHRSDRFYHAVAFTRVEL
HHHEEEEHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
VSAPATSLRNAIEQDASVGLLLLQGLSSRVLQTETMIETLTHRDMSSRLASFLLVLCRDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GVPGEKGVTIDLRLSHQAIAEAIGSTRVTITRLLGELKSSSLLAIDRKKITIFDPIALAK
CCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHH
RFN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366058; 8905231 [H]