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The map label for this gene is txlA [H]

Identifier: 124025033

GI number: 124025033

Start: 298341

End: 298910

Strand: Direct

Name: txlA [H]

Synonym: NATL1_03201

Alternate gene names: 124025033

Gene position: 298341-298910 (Clockwise)

Preceding gene: 124025032

Following gene: 124025037

Centisome position: 16.0

GC content: 31.4

Gene sequence:

>570_bases
ATGATTGATAACTCCAATTCAGATACAGCCCTTGGCCCCCGTCAAAAAATTTTTTTAGTTATACTAAGCTTCTTTTTAGT
TGTTTCACTATTCTTTTTTCGAACTGGGTTTAAAGCTAATGAAATGCTTGATCAATTGGCTAAGAACTCCTTGGAACCAG
AGATAGCTTTGTCAAATGGAAAACCTACAGTGTTTGAATTTTATGCTGATTGGTGTGAAGCTTGCAAGGAAATGGCTCCT
GAGATGGTTAATGCTGAAAAACTGAATTCAAATAAGATAGATATAGTTTTGCTTAATGTTGATAATTCAAGGTGGTTTGA
TTTGATTGATAAATATGATGTAAATGGCATTCCTCAATTAACTTTTTTTGACGATCAAGGTGACTTTAAGGGCTTTTCCT
TGGGAGTTAGAAAATATAGTGAACTTAATCAAATCTTTCTTGCTTTAATTAATAATTCTGAATTACCCGCTTTCACAAAA
TTATCAAATTCAAGTAATTTAATTTCTAAAAATAATTTAAAAGTTCTAGATAATAATATTAGATCAGAAGGCCCAAGGGA
TCATAGCTAG

Upstream 100 bases:

>100_bases
GCCTATTATTCACTAATTAATCAAATTTATAATTACAATATATGATATGTTTTAATTTAAAGTTTATGTATATAATCATT
AGTATGAAGTGTGAACTCGC

Downstream 100 bases:

>100_bases
AATAGCCAATTCAAAGCAGATGAAACTACTGGATATTCTTTTGAAAAAATATTTTTACATTCTTGTGCAATCTCCATATG
CTCTTTTTGCGTGCCATGAC

Product: thioredoxin-like protein TxlA

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MIDNSNSDTALGPRQKIFLVILSFFLVVSLFFFRTGFKANEMLDQLAKNSLEPEIALSNGKPTVFEFYADWCEACKEMAP
EMVNAEKLNSNKIDIVLLNVDNSRWFDLIDKYDVNGIPQLTFFDDQGDFKGFSLGVRKYSELNQIFLALINNSELPAFTK
LSNSSNLISKNNLKVLDNNIRSEGPRDHS

Sequences:

>Translated_189_residues
MIDNSNSDTALGPRQKIFLVILSFFLVVSLFFFRTGFKANEMLDQLAKNSLEPEIALSNGKPTVFEFYADWCEACKEMAP
EMVNAEKLNSNKIDIVLLNVDNSRWFDLIDKYDVNGIPQLTFFDDQGDFKGFSLGVRKYSELNQIFLALINNSELPAFTK
LSNSSNLISKNNLKVLDNNIRSEGPRDHS
>Mature_189_residues
MIDNSNSDTALGPRQKIFLVILSFFLVVSLFFFRTGFKANEMLDQLAKNSLEPEIALSNGKPTVFEFYADWCEACKEMAP
EMVNAEKLNSNKIDIVLLNVDNSRWFDLIDKYDVNGIPQLTFFDDQGDFKGFSLGVRKYSELNQIFLALINNSELPAFTK
LSNSSNLISKNNLKVLDNNIRSEGPRDHS

Specific function: Required for disulfide bond formation in some proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 21446; Mature: 21446

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNSNSDTALGPRQKIFLVILSFFLVVSLFFFRTGFKANEMLDQLAKNSLEPEIALSNG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCC
KPTVFEFYADWCEACKEMAPEMVNAEKLNSNKIDIVLLNVDNSRWFDLIDKYDVNGIPQL
CCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEE
TFFDDQGDFKGFSLGVRKYSELNQIFLALINNSELPAFTKLSNSSNLISKNNLKVLDNNI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEECCC
RSEGPRDHS
CCCCCCCCC
>Mature Secondary Structure
MIDNSNSDTALGPRQKIFLVILSFFLVVSLFFFRTGFKANEMLDQLAKNSLEPEIALSNG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCC
KPTVFEFYADWCEACKEMAPEMVNAEKLNSNKIDIVLLNVDNSRWFDLIDKYDVNGIPQL
CCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEE
TFFDDQGDFKGFSLGVRKYSELNQIFLALINNSELPAFTKLSNSSNLISKNNLKVLDNNI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEECCC
RSEGPRDHS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]