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The map label for this gene is aroC

Identifier: 124025017

GI number: 124025017

Start: 281855

End: 282940

Strand: Direct

Name: aroC

Synonym: NATL1_03041

Alternate gene names: 124025017

Gene position: 281855-282940 (Clockwise)

Preceding gene: 124025016

Following gene: 124025022

Centisome position: 15.12

GC content: 40.24

Gene sequence:

>1086_bases
ATGGGAAGTAGTTTCGGGAAACTTTTTACTATCAGCACCTTTGGCGAATCTCACGGAGGAGGTGTTGGTGTAATTATTGA
TGGATGTCCTCCAAGGTTGGAGCTCGACATTAACGAAATACAAAATGATCTCAATCGAAGGAGGCCAGGACAAAGCAAAA
TAACTACTCCAAGAAACGAAAGTGATGAAGTTGAAATTCTTAGTGGTCTTTTAGGTAATAAAACCTTAGGAACACCAATT
GCCATGGTTGTAAGAAATAAAGATCATCGGCCTAAGGATTATTCTGAAATTAAAAAAACTTTTAGGCCATCTCATGCTGA
TGCTACATATCAGAAAAAATACGGAATTCAGGCTTCAAGTGGCGGCGGGCGTGCATCAGCAAGAGAAACTATAGGTAGAG
TTGCTGCGGGTTCTGTTGCAAAGCAACTTCTAACTAAGTTTGCTAAAACGGAAATACTCGCTTGGGTAAAGAGAATTCAT
GATATTGAGGCTGAGATTCATCCGAGTGAAGTTACTTTTGATGAGATTGAGAAAAATATTGTTCGATGTCCAAATCAGTC
AGCTGCTGATTTAATGATTCAGAGAGTGGAGGCTTTTGGTAAAGAAGGAGACTCCTGTGGTGGAGTCATAGAATGTGTTG
TTCGGAATCCGCCCATAGGACTTGGTATGCCTGTTTTTGATAAATTAGAAGCTGATTTAGCAAAGGCATTAATGTCTTTG
CCTGCCACTAAAGGTTTTGAGGTGGGATCTGGTTTCGGAGGTACTTATTTGAAAGGCAGCGAACATAATGATCCTTTTTT
GCCATCCGATTCCAATCAATTGAAAACTGCCACTAACAATTCAGGCGGAATTCAAGGAGGTATCAGTAATGGTGAGGATA
TAGTACTAAGAGTAGGTTTTAAACCAACAGCAACTATTAGGAAAAGTCAAAAGACAATTGATGAGGATGGTAATGCAATA
ACTCTCAAGGCGACAGGAAGACATGATCCTTGTGTTTTGCCAAGGGCAGTTCCAATGGTTGAAGCAATGGTTGCGCTAGT
TTTAGCTGATCATTTACTAAGGCAAAGAGGCCAATGTACTGACTAA

Upstream 100 bases:

>100_bases
TTTAGAGGGCTTTTTTTTTGACTTTTTTTTGTTCTATGCATTACTTGAGTGGTTTATTTTTTAGCAAGTATTGATTAACA
TTTTGTAGATAGGTTTATTT

Downstream 100 bases:

>100_bases
TGTTCAAATAAATAATTATTTAAGATGCAATGCTAGACAAGGAATATATTGTTGATTTTTAGAATAGATTATCAGTAATC
CTCTAGCCATATTTCTAGGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MGSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNESDEVEILSGLLGNKTLGTPI
AMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASSGGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIH
DIEAEIHPSEVTFDEIEKNIVRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSL
PATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGFKPTATIRKSQKTIDEDGNAI
TLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCTD

Sequences:

>Translated_361_residues
MGSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNESDEVEILSGLLGNKTLGTPI
AMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASSGGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIH
DIEAEIHPSEVTFDEIEKNIVRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSL
PATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGFKPTATIRKSQKTIDEDGNAI
TLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCTD
>Mature_360_residues
GSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNESDEVEILSGLLGNKTLGTPIA
MVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASSGGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIHD
IEAEIHPSEVTFDEIEKNIVRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSLP
ATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGFKPTATIRKSQKTIDEDGNAIT
LKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCTD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=46.3888888888889, Blast_Score=303, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=55.3133514986376, Blast_Score=403, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PROM1 (A2C058)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014133.1
- ProteinModelPortal:   A2C058
- SMR:   A2C058
- STRING:   A2C058
- GeneID:   4780216
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_03041
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- BioCyc:   PMAR167555:NATL1_03041-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38831; Mature: 38699

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNE
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
SDEVEILSGLLGNKTLGTPIAMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASS
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCEECC
GGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIHDIEAEIHPSEVTFDEIEKNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSL
HCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECC
KPTATIRKSQKTIDEDGNAITLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCT
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
D
C
>Mature Secondary Structure 
GSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNE
CCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
SDEVEILSGLLGNKTLGTPIAMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASS
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCEECC
GGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIHDIEAEIHPSEVTFDEIEKNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSL
HCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECC
KPTATIRKSQKTIDEDGNAITLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCT
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA