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The map label for this gene is nusG [H]

Identifier: 124024994

GI number: 124024994

Start: 259385

End: 260053

Strand: Reverse

Name: nusG [H]

Synonym: NATL1_02811

Alternate gene names: 124024994

Gene position: 260053-259385 (Counterclockwise)

Preceding gene: 124024995

Following gene: 124024993

Centisome position: 13.95

GC content: 38.57

Gene sequence:

>669_bases
GTGTCAGAGATTGAAACCACCCCTGCTAAAGATTCAAAAATAATTGATAGATCAGAAGCAATTGAGGATGATCAATCATT
TCTTGCAAACCAATCAATCAAGACAAATATTGCACGGTGGTACGCTATTCAAGTTGCCTCAAGTTGCGAAAAGAAGGTAA
AAGCGACACTTGAGCAAAGAGCCATAACTCTTGGTGTCAGTGACAGAATAATAGAGATAGAAATCCCTCAAACACCAGCA
GTTAAGCTAAAAAAAGATGGTAGTAGGCAGACTACAGAAGAAAAAGTTTTCCCTGGATATGTGCTGGTTCGTATGGTTTT
AGATGAAGACACAATGATGGCTGTAAGAAGTACACCTAATGTAATTAATTTTGTTGGTGCAGAGGACCGCAGAGCTACTG
GTAAAGCACGCGGACACATAAAACCTCGCCCTCTCAGCAGGCAAGAAGTTAATAGGATTTTCAAACGAGCAGCTGAAAAG
AAAACTGTTGTCAAATTGGATGTAGAGGAAGGTGATCAGATTGTTGTAACTGCAGGTCCTTTTAAAGACTTCCAAGGAGA
AGTTATTGAAGTTTCAGGAGAACGAAACAAACTTAAGGCTCTTTTATCAATTTTTGGTAGAGAAACTCCAGTTGAACTTG
AATTTTCTCAAATAACTAAGCAAAATTGA

Upstream 100 bases:

>100_bases
ATCAATCGCAGCTGTAAGCCGTTTTTATGGATGGGCCTCTACTCAGATATTTCGCTGAGTTGACTAACCTAAATTTTTAA
ACCACTCACAATTTTTTCCA

Downstream 100 bases:

>100_bases
TTTTTAATTTCCTTTTGCTGTCTGGTCAGTCTAGGAGTTAAGTTTAATAGATAATTTAATCTGATTAATTTCAGGTTTTC
CGCATTAGTTCAATTTTCAG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSEIETTPAKDSKIIDRSEAIEDDQSFLANQSIKTNIARWYAIQVASSCEKKVKATLEQRAITLGVSDRIIEIEIPQTPA
VKLKKDGSRQTTEEKVFPGYVLVRMVLDEDTMMAVRSTPNVINFVGAEDRRATGKARGHIKPRPLSRQEVNRIFKRAAEK
KTVVKLDVEEGDQIVVTAGPFKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQITKQN

Sequences:

>Translated_222_residues
MSEIETTPAKDSKIIDRSEAIEDDQSFLANQSIKTNIARWYAIQVASSCEKKVKATLEQRAITLGVSDRIIEIEIPQTPA
VKLKKDGSRQTTEEKVFPGYVLVRMVLDEDTMMAVRSTPNVINFVGAEDRRATGKARGHIKPRPLSRQEVNRIFKRAAEK
KTVVKLDVEEGDQIVVTAGPFKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQITKQN
>Mature_221_residues
SEIETTPAKDSKIIDRSEAIEDDQSFLANQSIKTNIARWYAIQVASSCEKKVKATLEQRAITLGVSDRIIEIEIPQTPAV
KLKKDGSRQTTEEKVFPGYVLVRMVLDEDTMMAVRSTPNVINFVGAEDRRATGKARGHIKPRPLSRQEVNRIFKRAAEKK
TVVKLDVEEGDQIVVTAGPFKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQITKQN

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=184, Percent_Identity=38.5869565217391, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 24902; Mature: 24771

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIETTPAKDSKIIDRSEAIEDDQSFLANQSIKTNIARWYAIQVASSCEKKVKATLEQR
CCCCCCCCCCCCHHHCHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITLGVSDRIIEIEIPQTPAVKLKKDGSRQTTEEKVFPGYVLVRMVLDEDTMMAVRSTPN
EEEEECCCEEEEEECCCCCCEEEECCCCCCCCHHHCCCHHEEEEEHHCCCCEEEECCCCC
VINFVGAEDRRATGKARGHIKPRPLSRQEVNRIFKRAAEKKTVVKLDVEEGDQIVVTAGP
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECC
FKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQITKQN
CCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHCCCC
>Mature Secondary Structure 
SEIETTPAKDSKIIDRSEAIEDDQSFLANQSIKTNIARWYAIQVASSCEKKVKATLEQR
CCCCCCCCCCCHHHCHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITLGVSDRIIEIEIPQTPAVKLKKDGSRQTTEEKVFPGYVLVRMVLDEDTMMAVRSTPN
EEEEECCCEEEEEECCCCCCEEEECCCCCCCCHHHCCCHHEEEEEHHCCCCEEEECCCCC
VINFVGAEDRRATGKARGHIKPRPLSRQEVNRIFKRAAEKKTVVKLDVEEGDQIVVTAGP
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECC
FKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQITKQN
CCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685084; 8905231; 7505271 [H]