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The map label for this gene is pabA [H]

Identifier: 124024973

GI number: 124024973

Start: 237873

End: 238469

Strand: Direct

Name: pabA [H]

Synonym: NATL1_02601

Alternate gene names: 124024973

Gene position: 237873-238469 (Clockwise)

Preceding gene: 124024972

Following gene: 124024978

Centisome position: 12.76

GC content: 38.02

Gene sequence:

>597_bases
ATGTTTTTGGTGATTGACAATTATGACAGTTTCACTTATAACCTCGTTCAATATTTGGGCGAATTATCTTCTCAGCATCC
TATTGCATCAGAAGTAAGAGTCGAACGTAATGATGCTCTCACGATTAGTGAGATTAAAGATTTAAACCCTGATGCGATTT
TGTTATCTCCTGGTCCAGGAGATCCCAATCAATCTGGAGTTTGTCTGGATATTTTATCTGAGTTATCAATTGAAATACCC
ACCCTTGGTGTCTGTCTTGGTCATCAAGCTATTACACAAGCGTTCGGAGGGAAAATAATCAGAGCCAAAGAATTAATGCA
TGGCAAGACATCTAATGTTTTGCATAGAGGTACTGGAATATTTAAAGACTTGCCTAATCCCTTAGTAGCAACTAGATACC
ATAGCTTAATTGCCGAGAGAGAGAGTTTTCCAGAATGCTTAGAGGTTATAGCTTGGTTAGAGGATGAAACAATCATGGGA
ATATCTCATAAAGATTATCCGCACATATACGGCGTACAGTTTCATCCTGAGAGTGTATTAACTGAAGCTGGTCATAAGCT
ACTTTCTAATTTCCTAGATATAGCAAAAGCTACCTAG

Upstream 100 bases:

>100_bases
GGGGCAGTTTTAGTAGCCTCAATCAGTTCGGTGCTGATTGCTGTTTTATTATTATTTCCTCCATTACTTAAACAGTTAGG
AGTTTAATGGCTTAAAAATT

Downstream 100 bases:

>100_bases
ATTGTCTTATGCTTTGTAGACGTTATCAAATTATTTGAGCTATACTTCGTCGACAATTCTGAAAGCTGACCAGAATCTTT
TCATTTGGTCAATGGTTCCT

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MFLVIDNYDSFTYNLVQYLGELSSQHPIASEVRVERNDALTISEIKDLNPDAILLSPGPGDPNQSGVCLDILSELSIEIP
TLGVCLGHQAITQAFGGKIIRAKELMHGKTSNVLHRGTGIFKDLPNPLVATRYHSLIAERESFPECLEVIAWLEDETIMG
ISHKDYPHIYGVQFHPESVLTEAGHKLLSNFLDIAKAT

Sequences:

>Translated_198_residues
MFLVIDNYDSFTYNLVQYLGELSSQHPIASEVRVERNDALTISEIKDLNPDAILLSPGPGDPNQSGVCLDILSELSIEIP
TLGVCLGHQAITQAFGGKIIRAKELMHGKTSNVLHRGTGIFKDLPNPLVATRYHSLIAERESFPECLEVIAWLEDETIMG
ISHKDYPHIYGVQFHPESVLTEAGHKLLSNFLDIAKAT
>Mature_198_residues
MFLVIDNYDSFTYNLVQYLGELSSQHPIASEVRVERNDALTISEIKDLNPDAILLSPGPGDPNQSGVCLDILSELSIEIP
TLGVCLGHQAITQAFGGKIIRAKELMHGKTSNVLHRGTGIFKDLPNPLVATRYHSLIAERESFPECLEVIAWLEDETIMG
ISHKDYPHIYGVQFHPESVLTEAGHKLLSNFLDIAKAT

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=54.1666666666667, Blast_Score=227, Evalue=4e-61,
Organism=Escherichia coli, GI1787517, Length=198, Percent_Identity=38.8888888888889, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1786215, Length=156, Percent_Identity=32.0512820512821, Blast_Score=68, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=197, Percent_Identity=46.1928934010152, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=35.8490566037736, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21878; Mature: 21878

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVIDNYDSFTYNLVQYLGELSSQHPIASEVRVERNDALTISEIKDLNPDAILLSPGPG
CEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHEECCCCCEEHHHHHCCCCCEEEECCCCC
DPNQSGVCLDILSELSIEIPTLGVCLGHQAITQAFGGKIIRAKELMHGKTSNVLHRGTGI
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCHHHHCCCH
FKDLPNPLVATRYHSLIAERESFPECLEVIAWLEDETIMGISHKDYPHIYGVQFHPESVL
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECHHHHH
TEAGHKLLSNFLDIAKAT
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLVIDNYDSFTYNLVQYLGELSSQHPIASEVRVERNDALTISEIKDLNPDAILLSPGPG
CEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHEECCCCCEEHHHHHCCCCCEEEECCCCC
DPNQSGVCLDILSELSIEIPTLGVCLGHQAITQAFGGKIIRAKELMHGKTSNVLHRGTGI
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCHHHHCCCH
FKDLPNPLVATRYHSLIAERESFPECLEVIAWLEDETIMGISHKDYPHIYGVQFHPESVL
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECHHHHH
TEAGHKLLSNFLDIAKAT
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]