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The map label for this gene is anmK

Identifier: 124024865

GI number: 124024865

Start: 149826

End: 150962

Strand: Direct

Name: anmK

Synonym: NATL1_01521

Alternate gene names: 124024865

Gene position: 149826-150962 (Clockwise)

Preceding gene: 124024864

Following gene: 124024867

Centisome position: 8.03

GC content: 35.53

Gene sequence:

>1137_bases
ATGCGTGTATTGGGTTTGATGAGTGGTACGAGTGCGGATGGAATAGATGCAGTTTTAGTTGATTTTACAGGTGATCCTTC
AAAGCCAAAATGGCAAATTCTAAACACATTTTCTTATGAATATCCTTCATCAATTAGAGAAAAAATAATACAAGTAGGTC
AAGGATTAAAAATTAGTAGCAAAGATTGGCTCGAGTTGGCTGAGGAAATTACTGAACTAAATGCTTTTGCTGCTCGTACT
TGTGACCCTGATTCAACCGCAGAGGTTGTTGGATGTCACGGCCAAACTTTATTTCATAGAAGTGTAAAAAAATCTAAAAG
AGGAGGAAGTCTTCAAATTCTTTTAGGACCTTTACTCGCAAATCTTTTAGATCAAATTGTTATTTATGATTTTAGATCTA
AGGATATTGCTTCAGGTGGTCATGGTGCCCCTTTAGTAGCATTAGTCGATGAAGCTTTAGTTGGAAGGTTATATGGATGG
CGAGGAGTCCTCAACCTTGGTGGAATTGCTAATCTTACAATTATTCCACCTAAAACTGGAATTGATAAAACTTCTCAATG
CTTAGGCTGGGATTGCGGACCGGCTAATTCTTTAGTTGATTTAGCTGTTAAAGAAAGTACAAATTCATCTTTAACTTTTG
ATGAAAATGGATCATTAGCATCGCTTGGGATTCCTAAATTAGAAATCATCGATAAGTGGTTGAGGGATCCTTTTTTTTAT
CTAGAGCCTCCACGATCTACAGGTAGAGAACAATTCGGTTTTCAATACTTACAGAAAAGAAAAAAGGAATTGGGTGATAT
TTCCAAAGAAGATTTAATATCTACATTAACTACATTTACCGCGTCAATTATCTCTCAAGATTTAGATAATCTTTTTAAGT
TCAAACAGATACGTTTAATTGAGCTTTTGGTTGCTGGAGGTGGAAGTAAAAATCTATTTTTAATGAGGCAACTACAGAAA
CAATGTTGTGGTGTTCATGTGCGTCCAATAAATGAAATTGGTGTTCCATCGCAATATAGAGAAGCACTCGTTTTTGCAAC
TTTATCTTGGTGGAACTTTTTAGGAAAAAAAGTTAACCCGAAGTACATCACAGGAGCAAAGAAACCTATTTTATATGGTG
TACGTGTTGATCCTTAA

Upstream 100 bases:

>100_bases
AACTGTTAATCCTCCGGCGAAATATATTTTGGAAAAAGACCATGTCCTTGTAGTCATGGGCTCAATGGAAGATCTTCAAA
AGCTGCCTCAAACTTAATCT

Downstream 100 bases:

>100_bases
GTTAACTAATTTAATAGTTAATCTCTTTTGAATTTTAATCTTTTCGGAATACCTTTTAATCTTTGTGTTTTTTGTTTTTC
TAATGCGTTTATAAAATTTT

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISSKDWLELAEEITELNAFAART
CDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLANLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGW
RGVLNLGGIANLTIIPPKTGIDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFY
LEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLIELLVAGGGSKNLFLMRQLQK
QCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNPKYITGAKKPILYGVRVDP

Sequences:

>Translated_378_residues
MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISSKDWLELAEEITELNAFAART
CDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLANLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGW
RGVLNLGGIANLTIIPPKTGIDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFY
LEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLIELLVAGGGSKNLFLMRQLQK
QCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNPKYITGAKKPILYGVRVDP
>Mature_378_residues
MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISSKDWLELAEEITELNAFAART
CDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLANLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGW
RGVLNLGGIANLTIIPPKTGIDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFY
LEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLIELLVAGGGSKNLFLMRQLQK
QCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNPKYITGAKKPILYGVRVDP

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=378, Percent_Identity=30.952380952381, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_PROM1 (A2BZQ6)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001013981.1
- ProteinModelPortal:   A2BZQ6
- SMR:   A2BZQ6
- STRING:   A2BZQ6
- GeneID:   4779644
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_01521
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   PMAR167555:NATL1_01521-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 41677; Mature: 41677

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISS
CCEEEECCCCCCCCCEEEEEEECCCCCCCCEEEEEHHCCCCCHHHHHHHHHHCCCCEECC
KDWLELAEEITELNAFAARTCDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHCCCCCEEEEHHHHHH
NLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGWRGVLNLGGIANLTIIPPKTG
HHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
IDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFY
CCCHHHHCCCCCCCCCHHHHEEEECCCCCCEEECCCCCEEECCCCHHHHHHHHHHCCCEE
LEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLI
ECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLVAGGGSKNLFLMRQLQKQCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNP
HHHEECCCCCCHHHHHHHHHHHCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KYITGAKKPILYGVRVDP
CEECCCCCCEEEEEEECC
>Mature Secondary Structure
MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISS
CCEEEECCCCCCCCCEEEEEEECCCCCCCCEEEEEHHCCCCCHHHHHHHHHHCCCCEECC
KDWLELAEEITELNAFAARTCDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHCCCCCEEEEHHHHHH
NLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGWRGVLNLGGIANLTIIPPKTG
HHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
IDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFY
CCCHHHHCCCCCCCCCHHHHEEEECCCCCCEEECCCCCEEECCCCHHHHHHHHHHCCCEE
LEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLI
ECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLVAGGGSKNLFLMRQLQKQCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNP
HHHEECCCCCCHHHHHHHHHHHCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KYITGAKKPILYGVRVDP
CEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA