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The map label for this gene is coaX [H]

Identifier: 124024858

GI number: 124024858

Start: 142969

End: 143712

Strand: Reverse

Name: coaX [H]

Synonym: NATL1_01451

Alternate gene names: 124024858

Gene position: 143712-142969 (Counterclockwise)

Preceding gene: 124024859

Following gene: 124024856

Centisome position: 7.71

GC content: 32.26

Gene sequence:

>744_bases
ATGTGGGATCCATTTAAATACGCAATAACAAGGAATAAACTCGTGTACTCAGAAGAAAATTTCCTAATGATTGGCAATAC
AAGATGGCATTGGGCAAGCAAAGTTAAAAAAGATTGGAAATATTTTCATACCTCACCAAATCCAATCGAATTTAAAGATA
AGGATTATTCTCAATTAACCTGGGCCTCCGTTGGTCCCATCCCTGAGAATATTAAATTATGCCCTTCAAAAAAAATAATT
TTAGACAATGTTCCCCTAAACAATCTTCCATCTAATTTAGGAATTGACAGAGCTCTTTCTTCATGGAGTGCTTTTAAAAA
ACAATCATTTTTAAAAAGCAAAGAACAAGATTTAATTGTGATAGACGCAGGAACAATATTAAGCGTCACAAAAATATCAA
ACAAAGGAGAATTTATTGGGGGACAACTAATTTCCGGTTTCAGCCTTCAATTATCTTCAATGTCAAACCGTGCAATGAAT
TTAGAAACTCCCATTGTCAAAAAAATCCCAACTGAAACATTTCAATATGAGACTCACAATGCAATGATAAGAGGCTCAAT
GAATGCGTTAATAGGATTAATCTTAACACTTTTTGAGGAGACTAAATTACCGATATGGATGTGCGGTGGTGATGCTCCAA
TCATATTAAATGAACTCAAAAATACAAATATTGATATCAATCATTCTCCGAATCTAGTTCTAGAAGGAATGATTGATATA
TACAAAAAAATTAATTCAATTTAA

Upstream 100 bases:

>100_bases
TTGAAAAAGGTTATTCCACTGTAGGAGATTGGCATTCAAGCGGAGCAGAAAATACTAATACCAAAGGAAGGTCAACGAGA
TTTGGAGGCCTCAGTGAAGA

Downstream 100 bases:

>100_bases
GATCATTTAAAATCTGATTAGCCATATTATCTGATTTAACTTTTAAATATATTAATTCAATTTTCCCGTATTTGTTTACA
ACGAAAGTGTGTCTCATCAT

Product: transcriptional regulator

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MWDPFKYAITRNKLVYSEENFLMIGNTRWHWASKVKKDWKYFHTSPNPIEFKDKDYSQLTWASVGPIPENIKLCPSKKII
LDNVPLNNLPSNLGIDRALSSWSAFKKQSFLKSKEQDLIVIDAGTILSVTKISNKGEFIGGQLISGFSLQLSSMSNRAMN
LETPIVKKIPTETFQYETHNAMIRGSMNALIGLILTLFEETKLPIWMCGGDAPIILNELKNTNIDINHSPNLVLEGMIDI
YKKINSI

Sequences:

>Translated_247_residues
MWDPFKYAITRNKLVYSEENFLMIGNTRWHWASKVKKDWKYFHTSPNPIEFKDKDYSQLTWASVGPIPENIKLCPSKKII
LDNVPLNNLPSNLGIDRALSSWSAFKKQSFLKSKEQDLIVIDAGTILSVTKISNKGEFIGGQLISGFSLQLSSMSNRAMN
LETPIVKKIPTETFQYETHNAMIRGSMNALIGLILTLFEETKLPIWMCGGDAPIILNELKNTNIDINHSPNLVLEGMIDI
YKKINSI
>Mature_247_residues
MWDPFKYAITRNKLVYSEENFLMIGNTRWHWASKVKKDWKYFHTSPNPIEFKDKDYSQLTWASVGPIPENIKLCPSKKII
LDNVPLNNLPSNLGIDRALSSWSAFKKQSFLKSKEQDLIVIDAGTILSVTKISNKGEFIGGQLISGFSLQLSSMSNRAMN
LETPIVKKIPTETFQYETHNAMIRGSMNALIGLILTLFEETKLPIWMCGGDAPIILNELKNTNIDINHSPNLVLEGMIDI
YKKINSI

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28037; Mature: 28037

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDPFKYAITRNKLVYSEENFLMIGNTRWHWASKVKKDWKYFHTSPNPIEFKDKDYSQLT
CCCCEEEEEECCEEEEECCCEEEECCCCCHHHHHHHHHHHEECCCCCCCEECCCCCCEEE
WASVGPIPENIKLCPSKKIILDNVPLNNLPSNLGIDRALSSWSAFKKQSFLKSKEQDLIV
EEECCCCCCCCEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IDAGTILSVTKISNKGEFIGGQLISGFSLQLSSMSNRAMNLETPIVKKIPTETFQYETHN
EECCCEEEEEEECCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCCCEEECCCC
AMIRGSMNALIGLILTLFEETKLPIWMCGGDAPIILNELKNTNIDINHSPNLVLEGMIDI
EEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCEEECCCCCEEHHHHHHH
YKKINSI
HHHHHCC
>Mature Secondary Structure
MWDPFKYAITRNKLVYSEENFLMIGNTRWHWASKVKKDWKYFHTSPNPIEFKDKDYSQLT
CCCCEEEEEECCEEEEECCCEEEECCCCCHHHHHHHHHHHEECCCCCCCEECCCCCCEEE
WASVGPIPENIKLCPSKKIILDNVPLNNLPSNLGIDRALSSWSAFKKQSFLKSKEQDLIV
EEECCCCCCCCEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IDAGTILSVTKISNKGEFIGGQLISGFSLQLSSMSNRAMNLETPIVKKIPTETFQYETHN
EECCCEEEEEEECCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCCCEEECCCC
AMIRGSMNALIGLILTLFEETKLPIWMCGGDAPIILNELKNTNIDINHSPNLVLEGMIDI
EEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCEEECCCCCEEHHHHHHH
YKKINSI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]