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The map label for this gene is hit [C]

Identifier: 124024844

GI number: 124024844

Start: 127668

End: 128003

Strand: Reverse

Name: hit [C]

Synonym: NATL1_01311

Alternate gene names: 124024844

Gene position: 128003-127668 (Counterclockwise)

Preceding gene: 124024845

Following gene: 124024843

Centisome position: 6.86

GC content: 36.01

Gene sequence:

>336_bases
ATGACAACAATCTTCGATAAAATTCTTAGCGGTGAAATTCCATGTGATGAGGTTTTTAGTGATAACAAATGCCTAGCTTT
CAAAGATATAACCCCTCAAGCACCTACTCACATTTTAATAATTCCTAGAAAACCTATTCCAAGTCTGCAAGATATAAAAA
AAGAAGATCAAGAATTACTTGGGCATTTACTGCTAAAAGGGACCGAAATTGCTAATGCTGCTGGTTTAGAAAGTTGGAGA
ACCATAATTAATACAGGAGAAGAAGCAGGTCAAACAGTCTTTCACTTACATATTCATATCATTGGCGGAAGGAAGTTAAG
TTGGCCACCTGGATAA

Upstream 100 bases:

>100_bases
GCGAAGCGATGTAATAAAAGCAACGAATTGAAAAAATCTTGTCAATTCAAGCTATAAAAAATCGCATTAGATTCTTCTTA
TTGCTCTCTACACAAATTCA

Downstream 100 bases:

>100_bases
ATAATTCATTTCTTTTGATCAATCAGCACGATTGCCTTACTGGCTTAGTTGCTGACTCATTTCCACCCATTGATGCGCTA
TAAGGTAGTTAAATAATCTT

Product: HIT (histidine triad) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MTTIFDKILSGEIPCDEVFSDNKCLAFKDITPQAPTHILIIPRKPIPSLQDIKKEDQELLGHLLLKGTEIANAAGLESWR
TIINTGEEAGQTVFHLHIHIIGGRKLSWPPG

Sequences:

>Translated_111_residues
MTTIFDKILSGEIPCDEVFSDNKCLAFKDITPQAPTHILIIPRKPIPSLQDIKKEDQELLGHLLLKGTEIANAAGLESWR
TIINTGEEAGQTVFHLHIHIIGGRKLSWPPG
>Mature_110_residues
TTIFDKILSGEIPCDEVFSDNKCLAFKDITPQAPTHILIIPRKPIPSLQDIKKEDQELLGHLLLKGTEIANAAGLESWRT
IINTGEEAGQTVFHLHIHIIGGRKLSWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=110, Percent_Identity=51.8181818181818, Blast_Score=135, Evalue=8e-33,
Organism=Homo sapiens, GI4885413, Length=110, Percent_Identity=48.1818181818182, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1787346, Length=106, Percent_Identity=46.2264150943396, Blast_Score=91, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17506713, Length=110, Percent_Identity=42.7272727272727, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574010, Length=110, Percent_Identity=52.7272727272727, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24581222, Length=110, Percent_Identity=52.7272727272727, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12289; Mature: 12158

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIFDKILSGEIPCDEVFSDNKCLAFKDITPQAPTHILIIPRKPIPSLQDIKKEDQELL
CCHHHHHHHCCCCCHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
GHLLLKGTEIANAAGLESWRTIINTGEEAGQTVFHLHIHIIGGRKLSWPPG
HHHHHCCCCCCCCCCHHHHHHHHHCCHHCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TTIFDKILSGEIPCDEVFSDNKCLAFKDITPQAPTHILIIPRKPIPSLQDIKKEDQELL
CHHHHHHHCCCCCHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
GHLLLKGTEIANAAGLESWRTIINTGEEAGQTVFHLHIHIIGGRKLSWPPG
HHHHHCCCCCCCCCCHHHHHHHHHCCHHCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]