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The map label for this gene is coaE [H]

Identifier: 124024776

GI number: 124024776

Start: 69676

End: 70320

Strand: Reverse

Name: coaE [H]

Synonym: NATL1_00631

Alternate gene names: 124024776

Gene position: 70320-69676 (Counterclockwise)

Preceding gene: 124024779

Following gene: 124024774

Centisome position: 3.77

GC content: 29.77

Gene sequence:

>645_bases
ATGATTGACCAAAAACAAACAAACAATCTTTGTCTTAGATGGAAAGGCAAGCAGAGAAGAATAGGTATCACTGGGGGTAT
CGCCAGTGGAAAAACAATCATTGGAGATTTTCTATTTCAAGCCAAGCAATGGCCTATTTTAGACGCTGACTTATACGCTC
ATGAAGCATTAAGTGCTGAAAGTGAAATAGTCAAAAAAGTCTGGTTGAGATATGGAAGTAAAATAATTAAAAATTCAAGT
AAAAATGATCACATTATTAATCGAAAAGCATTGGCCAAAATAGTTTTTCAAAATGAAATTGAAAAAAAATGGCTAGAGGG
AATAATACATCCATTCGTCAACAAAAGAATTGAAGAAGAATTAGAAAAATTGAAATCAAATTCAATTGTAATTTTGATTA
TTCCACTCCTATTTGAAAAAAATTATACAGGGTTATGTAGTGAAATTTGTTACATAGATTGCACTAGAAGTATGCAATTA
AAGCGACTTCAGTCAAGAGATCATTTAAGTATTAAAGAAGCAAATCAAAGAATTGATGCTCAATGGGCAAACTCTTTGAA
AAAACAATTTGCAGATCACATCATTAATAACTCTAATGATGATGAGACATGGAAATTACAATTAAAAAAATTATATAAAT
TCTAA

Upstream 100 bases:

>100_bases
AACCATCAGGGGCAGTAATACCACCAGATATTGGAGACCATACAGAAGATGTCAAAAGACTCAAGTTCAGAAGAGCATTT
TTCACTTACTATCAATATTA

Downstream 100 bases:

>100_bases
CCTTGTAATTTTTTATTTAATATTTGATTAGCGAGTTTTGGATCTGCTTTCCCTTTTGTTTCCTTCATTAATTGACCAAC
AAAAAACCCTAACAATTTCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIDQKQTNNLCLRWKGKQRRIGITGGIASGKTIIGDFLFQAKQWPILDADLYAHEALSAESEIVKKVWLRYGSKIIKNSS
KNDHIINRKALAKIVFQNEIEKKWLEGIIHPFVNKRIEEELEKLKSNSIVILIIPLLFEKNYTGLCSEICYIDCTRSMQL
KRLQSRDHLSIKEANQRIDAQWANSLKKQFADHIINNSNDDETWKLQLKKLYKF

Sequences:

>Translated_214_residues
MIDQKQTNNLCLRWKGKQRRIGITGGIASGKTIIGDFLFQAKQWPILDADLYAHEALSAESEIVKKVWLRYGSKIIKNSS
KNDHIINRKALAKIVFQNEIEKKWLEGIIHPFVNKRIEEELEKLKSNSIVILIIPLLFEKNYTGLCSEICYIDCTRSMQL
KRLQSRDHLSIKEANQRIDAQWANSLKKQFADHIINNSNDDETWKLQLKKLYKF
>Mature_214_residues
MIDQKQTNNLCLRWKGKQRRIGITGGIASGKTIIGDFLFQAKQWPILDADLYAHEALSAESEIVKKVWLRYGSKIIKNSS
KNDHIINRKALAKIVFQNEIEKKWLEGIIHPFVNKRIEEELEKLKSNSIVILIIPLLFEKNYTGLCSEICYIDCTRSMQL
KRLQSRDHLSIKEANQRIDAQWANSLKKQFADHIINNSNDDETWKLQLKKLYKF

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=183, Percent_Identity=31.6939890710383, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI191252795, Length=183, Percent_Identity=31.6939890710383, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=24.4791666666667, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554944, Length=185, Percent_Identity=28.1081081081081, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320402, Length=182, Percent_Identity=31.8681318681319, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24644728, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658602, Length=226, Percent_Identity=24.7787610619469, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24969; Mature: 24969

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDQKQTNNLCLRWKGKQRRIGITGGIASGKTIIGDFLFQAKQWPILDADLYAHEALSAE
CCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCHH
SEIVKKVWLRYGSKIIKNSSKNDHIINRKALAKIVFQNEIEKKWLEGIIHPFVNKRIEEE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKLKSNSIVILIIPLLFEKNYTGLCSEICYIDCTRSMQLKRLQSRDHLSIKEANQRIDA
HHHHCCCCEEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
QWANSLKKQFADHIINNSNDDETWKLQLKKLYKF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIDQKQTNNLCLRWKGKQRRIGITGGIASGKTIIGDFLFQAKQWPILDADLYAHEALSAE
CCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCHH
SEIVKKVWLRYGSKIIKNSSKNDHIINRKALAKIVFQNEIEKKWLEGIIHPFVNKRIEEE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKLKSNSIVILIIPLLFEKNYTGLCSEICYIDCTRSMQLKRLQSRDHLSIKEANQRIDA
HHHHCCCCEEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
QWANSLKKQFADHIINNSNDDETWKLQLKKLYKF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA