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The map label for this gene is cbiD

Identifier: 124024747

GI number: 124024747

Start: 33942

End: 35087

Strand: Direct

Name: cbiD

Synonym: NATL1_00341

Alternate gene names: 124024747

Gene position: 33942-35087 (Clockwise)

Preceding gene: 124024745

Following gene: 124024748

Centisome position: 1.82

GC content: 36.74

Gene sequence:

>1146_bases
TTGAATCAATTTACTCTTCCCGTTTGGGTGGTTGCTGCTGCAAAGTCAGCAACGAATATTCTTATTGGTAATAAATTTAG
GGATAAAGAGCGAATTGATTTACCAAATAAAGAAGAATCGATTTCGGTACCTATTTCTTCTTCTGCTTTACTCGATAACG
GTAAAAGATCTTTAGCAGTAAGTCATTGTCAGTCTGGATTGCCTCTTGACATAACAAGAGGAGTAGAAATCTGGGCTTAT
ATTCAATTAAGTAAAGGAAGTTCTCAATCTAAAGGGAAAGTTCAAAATGGTTTTCCTGATTGGCTTGATTTTCATGCCGG
TTGTGGAGTAGGTAAATTTCAATCATCTGGTCAGCCATGTATTTCTCAGTTTGCGCGTGACTTGCTATGTATTAATCTTT
ACCCTCTTGTACCCAAAGGTAATTCAATTAAAGTTGAGATTATTTTACCTGAAGGGAAAGATCGTGCATCAAAGACAAGT
AATGAAGCCTTTGGAGTTGTAGATGGATTGTCCCTCATTGGGACCCAGGCTGAGGTTCAAATTAGTGCTTCTCCAGATCA
GTTGAAAAACTGCAAAGAGATTTTGTACCACAAATGCTCTGAAGCAAAATTTGATGGATGTTTGACTTTTGTGATTGGTG
AAAATGGAATGGATTTAGCGATGAAATATGGCCTGCCAGCTAATCAAATTATTAAAACCGGGAATTGGCTAGGTCCTCTT
CTTGTTGCTGCTGCAGAAAATGGAGTCAAGAAACTTTTATTATTTGGATATCATGGAAAACTTATAAAACTTTCTGGCGG
CGTTTTTCATACACATCATCATCTTGCTGATGGAAGGATTGAAATACTCACGTCACTTGCATTCAGAGAAGGAATCTCAT
TTGATTTGATTGAGTTAATAAGTAAATCAACATCAGTGGAAAATGCTTTATTAACCCTTGAAGTAAGTAACCCAGATGCT
GTGTCTTTGATATGGAGCAGGATGGCTAAAGAAATTGAAATTAAAAGCAGAAGCTATGTGAATAGATACTTGTCTTCATC
AATGGAAATAGGATCTGTTTTATTTGATCGTAAGAGACAAATGCGTTGGGCTGGTCTTGAGGGTTTAAAACAGATTAATT
CTTTGGGGTTAATTCTTAAGCGATAG

Upstream 100 bases:

>100_bases
TAAATTGAGTTTGTCCTGCATTTACTTATTCAAATCTAGATTAAGATTATTTTAAAAAATTATTTAGGGAATTTCCTTTA
TCGTCAGCTCTTCCAATGAT

Downstream 100 bases:

>100_bases
GCATATTCCTATTCTCTTAATTAGTCTATTTGATAAGAATGTTTTATAAGGATTCATCAGGTTGATATGGCTTCAATGAT
TTCAGCTGAAAAACGTAATC

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNKEESISVPISSSALLDNGKRSLAVSHCQSGLPLDITRGVEIWAY
IQLSKGSSQSKGKVQNGFPDWLDFHAGCGVGKFQSSGQPCISQFARDLLCINLYPLVPKGNSIKVEIILPEGKDRASKTS
NEAFGVVDGLSLIGTQAEVQISASPDQLKNCKEILYHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPL
LVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSLAFREGISFDLIELISKSTSVENALLTLEVSNPDA
VSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQMRWAGLEGLKQINSLGLILKR

Sequences:

>Translated_381_residues
MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNKEESISVPISSSALLDNGKRSLAVSHCQSGLPLDITRGVEIWAY
IQLSKGSSQSKGKVQNGFPDWLDFHAGCGVGKFQSSGQPCISQFARDLLCINLYPLVPKGNSIKVEIILPEGKDRASKTS
NEAFGVVDGLSLIGTQAEVQISASPDQLKNCKEILYHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPL
LVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSLAFREGISFDLIELISKSTSVENALLTLEVSNPDA
VSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQMRWAGLEGLKQINSLGLILKR
>Mature_381_residues
MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNKEESISVPISSSALLDNGKRSLAVSHCQSGLPLDITRGVEIWAY
IQLSKGSSQSKGKVQNGFPDWLDFHAGCGVGKFQSSGQPCISQFARDLLCINLYPLVPKGNSIKVEIILPEGKDRASKTS
NEAFGVVDGLSLIGTQAEVQISASPDQLKNCKEILYHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPL
LVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSLAFREGISFDLIELISKSTSVENALLTLEVSNPDA
VSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQMRWAGLEGLKQINSLGLILKR

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_PROM1 (A2BZD8)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001013863.1
- ProteinModelPortal:   A2BZD8
- STRING:   A2BZD8
- GeneID:   4780273
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_00341
- eggNOG:   COG1903
- HOGENOM:   HBG285971
- OMA:   THHHLAD
- ProtClustDB:   PRK00075
- BioCyc:   PMAR167555:NATL1_00341-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 41730; Mature: 41730

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNKEESISVPISSSALLDNGKRSLAV
CCCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCHHEEH
SHCQSGLPLDITRGVEIWAYIQLSKGSSQSKGKVQNGFPDWLDFHAGCGVGKFQSSGQPC
HHHCCCCCEEEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHH
ISQFARDLLCINLYPLVPKGNSIKVEIILPEGKDRASKTSNEAFGVVDGLSLIGTQAEVQ
HHHHHHHEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEE
ISASPDQLKNCKEILYHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPL
EECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCHHHH
LVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSLAFREGISFDLIELI
HHHHHHCCCEEEEEEECCCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
SKSTSVENALLTLEVSNPDAVSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQ
HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MRWAGLEGLKQINSLGLILKR
HHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNKEESISVPISSSALLDNGKRSLAV
CCCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCHHEEH
SHCQSGLPLDITRGVEIWAYIQLSKGSSQSKGKVQNGFPDWLDFHAGCGVGKFQSSGQPC
HHHCCCCCEEEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHH
ISQFARDLLCINLYPLVPKGNSIKVEIILPEGKDRASKTSNEAFGVVDGLSLIGTQAEVQ
HHHHHHHEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEE
ISASPDQLKNCKEILYHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPL
EECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCHHHH
LVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSLAFREGISFDLIELI
HHHHHHCCCEEEEEEECCCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
SKSTSVENALLTLEVSNPDAVSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQ
HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MRWAGLEGLKQINSLGLILKR
HHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA