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The map label for this gene is ftsY [H]

Identifier: 124024722

GI number: 124024722

Start: 11983

End: 13278

Strand: Direct

Name: ftsY [H]

Synonym: NATL1_00091

Alternate gene names: 124024722

Gene position: 11983-13278 (Clockwise)

Preceding gene: 124024721

Following gene: 124024723

Centisome position: 0.64

GC content: 35.19

Gene sequence:

>1296_bases
ATGAAAGAAGATTGTTCTCAGGACGAAAAGAATTTTTCTAAGATGAATCAAAGCGAGAATTCGTCATCTATGAATGATGA
CTCTTTAGATTGGGCAAAACAAGCTTATTTGCAACTCAAACAAAAGCAAAAAGAGGAAAAAGAGTTATGTCAAAAAGAAA
TTGCAGAAAAAGAGATATTGAAAACTAAAACAAATACAAGCGAGGATTTTAAATCAAATATTACAGTTGAAAATAGTCTG
CAAGTTAGTCAAGAGACAGAAGTAGAAGATCAGCCTCAATTAGGAGATTTTGATGATACTTTTACATGGTCAGCGGAAGT
GTTAGCTGCCCAAGGTAAAAAAATTGACCAATTTTCATTAGATGATATTGATTGGCTCAGCAGACTGAAGCAAGGATTAG
AGAAAACTCGTAAAGGCTTTGTTACTGATTTATTAGAAAAATTAGGAGATGATCCACTTACTCCTGAAGTTCTTGATGAT
TTAGAAACTCTTTTACTTAGAGCAGATGCGGGAGTTTCTGCTACTGATCAAATTTTAGAATCTCTAAGAACCAAGTTAAA
TGAGGAAGTTGTTGAAGCTTCAGAGGGCTTGCGTTTTTTAAAAGAACAATTAGTCAATGTTTTAGAAAAACCAATAAAAG
ATAGTGGTGCTGATTTACTTTCTCCACAAAAAGGTTGTTTAAATATTTGGATGCTAGTAGGTGTTAATGGAGTTGGAAAA
ACGACGACCCTGGGTAAATTGGCAAGTGTTGCAAAAAGAAGTGGTTTTTCAGCAATGATTGCGGCTGCAGACACTTTTAG
AGCTGCAGCTGTTCAACAAGTAAAGGTATGGGGAGACAGAACAGGGGTTGAAGTTATCGCAAATGAATCTAAGAATGCCG
ATCCAGCATCGATAGTATTTGATGCTATTGGTGCAAGTAAATCAAAAAATATAGACTTACTATTGGTAGATACGGCAGGA
AGATTACAAACGAAAAATAATTTAATGGAGGAATTGAAAAAAATTAGAAAAATTATCGATAAACTTGCTCCTAAGGCAAA
CGTTGAATCTTTATTAGTACTTGATTCTAGTCAAGGTCAAAATGGCCTAAGGCAAGCTCTAGCATTTGCTGATTCAGCAG
AATTAACAGGCGTAATACTTACAAAACTTGATGGATCTTCTAAAGGAGGTGTTGCTATGGCTGTTGCATCAGAAGCAAAA
CTTCCTGTCAGATTTATCGGAGCTGGTGAGAAAATTAGAGACTTGCGACCATTTAATAGCTTTGAATTTATTGAGGCACT
TTTAACTGTTAGATGA

Upstream 100 bases:

>100_bases
CTGTAAATTTGGCTAATCGTTATAGCGATGTACAAGGACGCAGAATGATTAATGGAGTTTTAAGGAAACTTCAAAATTCT
GCTTTGATACTAAACTTGAA

Downstream 100 bases:

>100_bases
TTTTTAGATATTTTTTGTATATGTTGCTAAGTTTTAATTTCTTTATTGTCGGAGAATGGTGAAAGAAAATTCTCCAATTT
CAGAACAACAAAATCAACAT

Product: signal recognition particle docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKEDCSQDEKNFSKMNQSENSSSMNDDSLDWAKQAYLQLKQKQKEEKELCQKEIAEKEILKTKTNTSEDFKSNITVENSL
QVSQETEVEDQPQLGDFDDTFTWSAEVLAAQGKKIDQFSLDDIDWLSRLKQGLEKTRKGFVTDLLEKLGDDPLTPEVLDD
LETLLLRADAGVSATDQILESLRTKLNEEVVEASEGLRFLKEQLVNVLEKPIKDSGADLLSPQKGCLNIWMLVGVNGVGK
TTTLGKLASVAKRSGFSAMIAAADTFRAAAVQQVKVWGDRTGVEVIANESKNADPASIVFDAIGASKSKNIDLLLVDTAG
RLQTKNNLMEELKKIRKIIDKLAPKANVESLLVLDSSQGQNGLRQALAFADSAELTGVILTKLDGSSKGGVAMAVASEAK
LPVRFIGAGEKIRDLRPFNSFEFIEALLTVR

Sequences:

>Translated_431_residues
MKEDCSQDEKNFSKMNQSENSSSMNDDSLDWAKQAYLQLKQKQKEEKELCQKEIAEKEILKTKTNTSEDFKSNITVENSL
QVSQETEVEDQPQLGDFDDTFTWSAEVLAAQGKKIDQFSLDDIDWLSRLKQGLEKTRKGFVTDLLEKLGDDPLTPEVLDD
LETLLLRADAGVSATDQILESLRTKLNEEVVEASEGLRFLKEQLVNVLEKPIKDSGADLLSPQKGCLNIWMLVGVNGVGK
TTTLGKLASVAKRSGFSAMIAAADTFRAAAVQQVKVWGDRTGVEVIANESKNADPASIVFDAIGASKSKNIDLLLVDTAG
RLQTKNNLMEELKKIRKIIDKLAPKANVESLLVLDSSQGQNGLRQALAFADSAELTGVILTKLDGSSKGGVAMAVASEAK
LPVRFIGAGEKIRDLRPFNSFEFIEALLTVR
>Mature_431_residues
MKEDCSQDEKNFSKMNQSENSSSMNDDSLDWAKQAYLQLKQKQKEEKELCQKEIAEKEILKTKTNTSEDFKSNITVENSL
QVSQETEVEDQPQLGDFDDTFTWSAEVLAAQGKKIDQFSLDDIDWLSRLKQGLEKTRKGFVTDLLEKLGDDPLTPEVLDD
LETLLLRADAGVSATDQILESLRTKLNEEVVEASEGLRFLKEQLVNVLEKPIKDSGADLLSPQKGCLNIWMLVGVNGVGK
TTTLGKLASVAKRSGFSAMIAAADTFRAAAVQQVKVWGDRTGVEVIANESKNADPASIVFDAIGASKSKNIDLLLVDTAG
RLQTKNNLMEELKKIRKIIDKLAPKANVESLLVLDSSQGQNGLRQALAFADSAELTGVILTKLDGSSKGGVAMAVASEAK
LPVRFIGAGEKIRDLRPFNSFEFIEALLTVR

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the membrane [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=274, Percent_Identity=35.036496350365, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI226371618, Length=215, Percent_Identity=37.2093023255814, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI23308697, Length=302, Percent_Identity=28.8079470198675, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI295424842, Length=302, Percent_Identity=28.8079470198675, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=37.7777777777778, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1789874, Length=312, Percent_Identity=46.474358974359, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788963, Length=271, Percent_Identity=29.1512915129151, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17539958, Length=294, Percent_Identity=31.6326530612245, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193206261, Length=320, Percent_Identity=30.625, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=281, Percent_Identity=31.3167259786477, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=215, Percent_Identity=30.6976744186047, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647949, Length=275, Percent_Identity=33.0909090909091, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24641198, Length=251, Percent_Identity=29.8804780876494, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 47302; Mature: 47302

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00180 GLNA_1 ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]