Click here to switch to the map view.

The map label for this gene is 124028491

Identifier: 124028491

GI number: 124028491

Start: 1645485

End: 1646522

Strand: Reverse

Name: 124028491

Synonym: Hbut_1652

Alternate gene names: NA

Gene position: 1646522-1645485 (Counterclockwise)

Preceding gene: 124028492

Following gene: 124028490

Centisome position: 98.76

GC content: 52.7

Gene sequence:

>1038_bases
GTGAGCAGAAGCTCTGACTGTGTAAGAATAGTTGATGGTTATCTCTTCGATTTTTCCAAACTCATAGAGCATGTCCGGAG
GTATGGCTACAAGAGGCTTCTCCTCGAAGCACCTCCTGGCATGTTGCACCTCTCCGAAAAACTCTCCAGCATCATAGCTG
AATGTTTAGGGGAGGACATCGAGGTAATCATCCGCCTCGAGCCAGTTTACGGGTCTTGTAGCACATCGTTACAACTCCTC
AGTCAAGGATTTGTGGACGCCATAGTACACATAGGCCACGACGAGTACCCCTACCCCCTCTGTATGGGTAGCCGATGCCT
CTACACCACACCGCCAAGAGTATTCTATGTTGAGGGTGAGTATGTTGGTGCTGACTTCTCCAGTCTTGCAACGCGGATCG
TCGAAACCGTAAAAGCCCCAACGCTAGCCATAGGCTTCCCAGCCCAGCACAAGAGGCTCGGTATACGTGTTGCAGAGCTC
CTAGCGAAGTGGGGGGTCAAGGTTAAGGCGGCAGCTAGGATTCTCGGCTGCTACTACCAGCCACTAGTGAGGAGCAATGC
GGACGCCTATGTTGTTATTGCCGGTGGCTACTTCCACGCCATAGGTTTAGCACTGGCCCTAGAGGCTTCAAAGCCTGTCT
ACCGTGCCGATCCATATACCGGGACTGTGGAGAATGTAACGGGTACTGCGAGGCGCTGGCTTGCAAAACGATACTGGGTG
ATAAGACAAGCGATGAGTGCAGATAGGTTTGGGGTAATAGTAGGCTTGCTTCCCGGCCAGTATAGGCCTGGCGTCGTTGA
GGCAGTCACGAAGCTCCTCCGAAGAGCTGGCAAAAGCTATAGGCTGCTATACAGTGAGAGGCTTAGCAGGGAATACCTTG
ACAATCTCTCGCCAGACGACTACGATGCCTTCATAGTAACGTCTTGTCCCAGGCTTGCAATAGAGGATCTTGGTGACTAC
TGGAAGCCCGTACTAACGCCGGGAGAAGCGTTTGTAGCTATCACGGGTAGGCTGGAGAGGTACCGTTTCCCCTGGTAG

Upstream 100 bases:

>100_bases
ATGCAAAGGAGGCACTAAGGCGTGGCGCCTCAAAGCTTCCACTACCATCCCGTATCCGTGTCATACCGTTAAAGGAGGAG
GCTAAGGCGGCTGCATAACA

Downstream 100 bases:

>100_bases
AGGGTGAGGTAGCATTAAGGAGCTACCAAGACTCTCAAGGATAGTGATTACCCTAGAGAGATATGTGCCAGAATTTACGC
GGCCTAAACGCGAGCTCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSRSSDCVRIVDGYLFDFSKLIEHVRRYGYKRLLLEAPPGMLHLSEKLSSIIAECLGEDIEVIIRLEPVYGSCSTSLQLL
SQGFVDAIVHIGHDEYPYPLCMGSRCLYTTPPRVFYVEGEYVGADFSSLATRIVETVKAPTLAIGFPAQHKRLGIRVAEL
LAKWGVKVKAAARILGCYYQPLVRSNADAYVVIAGGYFHAIGLALALEASKPVYRADPYTGTVENVTGTARRWLAKRYWV
IRQAMSADRFGVIVGLLPGQYRPGVVEAVTKLLRRAGKSYRLLYSERLSREYLDNLSPDDYDAFIVTSCPRLAIEDLGDY
WKPVLTPGEAFVAITGRLERYRFPW

Sequences:

>Translated_345_residues
MSRSSDCVRIVDGYLFDFSKLIEHVRRYGYKRLLLEAPPGMLHLSEKLSSIIAECLGEDIEVIIRLEPVYGSCSTSLQLL
SQGFVDAIVHIGHDEYPYPLCMGSRCLYTTPPRVFYVEGEYVGADFSSLATRIVETVKAPTLAIGFPAQHKRLGIRVAEL
LAKWGVKVKAAARILGCYYQPLVRSNADAYVVIAGGYFHAIGLALALEASKPVYRADPYTGTVENVTGTARRWLAKRYWV
IRQAMSADRFGVIVGLLPGQYRPGVVEAVTKLLRRAGKSYRLLYSERLSREYLDNLSPDDYDAFIVTSCPRLAIEDLGDY
WKPVLTPGEAFVAITGRLERYRFPW
>Mature_344_residues
SRSSDCVRIVDGYLFDFSKLIEHVRRYGYKRLLLEAPPGMLHLSEKLSSIIAECLGEDIEVIIRLEPVYGSCSTSLQLLS
QGFVDAIVHIGHDEYPYPLCMGSRCLYTTPPRVFYVEGEYVGADFSSLATRIVETVKAPTLAIGFPAQHKRLGIRVAELL
AKWGVKVKAAARILGCYYQPLVRSNADAYVVIAGGYFHAIGLALALEASKPVYRADPYTGTVENVTGTARRWLAKRYWVI
RQAMSADRFGVIVGLLPGQYRPGVVEAVTKLLRRAGKSYRLLYSERLSREYLDNLSPDDYDAFIVTSCPRLAIEDLGDYW
KPVLTPGEAFVAITGRLERYRFPW

Specific function: Unknown

COG id: COG1736

COG function: function code J; Diphthamide synthase subunit DPH2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116686106, Length=334, Percent_Identity=27.8443113772455, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17552166, Length=332, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322088, Length=336, Percent_Identity=27.0833333333333, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016435
- InterPro:   IPR002728
- InterPro:   IPR022428 [H]

Pfam domain/function: PF01866 Diphthamide_syn [H]

EC number: NA

Molecular weight: Translated: 38692; Mature: 38561

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSSDCVRIVDGYLFDFSKLIEHVRRYGYKRLLLEAPPGMLHLSEKLSSIIAECLGEDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCE
EVIIRLEPVYGSCSTSLQLLSQGFVDAIVHIGHDEYPYPLCMGSRCLYTTPPRVFYVEGE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCEEEEEECC
YVGADFSSLATRIVETVKAPTLAIGFPAQHKRLGIRVAELLAKWGVKVKAAARILGCYYQ
EECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PLVRSNADAYVVIAGGYFHAIGLALALEASKPVYRADPYTGTVENVTGTARRWLAKRYWV
HHHHCCCCEEEEEECCHHHHHHHHHHEECCCCCEECCCCCCCHHCCHHHHHHHHHHHHHH
IRQAMSADRFGVIVGLLPGQYRPGVVEAVTKLLRRAGKSYRLLYSERLSREYLDNLSPDD
HHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
YDAFIVTSCPRLAIEDLGDYWKPVLTPGEAFVAITGRLERYRFPW
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCC
>Mature Secondary Structure 
SRSSDCVRIVDGYLFDFSKLIEHVRRYGYKRLLLEAPPGMLHLSEKLSSIIAECLGEDI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCE
EVIIRLEPVYGSCSTSLQLLSQGFVDAIVHIGHDEYPYPLCMGSRCLYTTPPRVFYVEGE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCEEEEEECC
YVGADFSSLATRIVETVKAPTLAIGFPAQHKRLGIRVAELLAKWGVKVKAAARILGCYYQ
EECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PLVRSNADAYVVIAGGYFHAIGLALALEASKPVYRADPYTGTVENVTGTARRWLAKRYWV
HHHHCCCCEEEEEECCHHHHHHHHHHEECCCCCEECCCCCCCHHCCHHHHHHHHHHHHHH
IRQAMSADRFGVIVGLLPGQYRPGVVEAVTKLLRRAGKSYRLLYSERLSREYLDNLSPDD
HHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
YDAFIVTSCPRLAIEDLGDYWKPVLTPGEAFVAITGRLERYRFPW
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]