BacMap

Definition	Hyperthermus butylicus DSM 5456 chromosome, complete genome.
Accession	NC_008818
Length	1,667,163

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The map label for this gene is lolD [C]

Identifier: 124028259

GI number: 124028259

Start: 1412133

End: 1412828

Strand: Direct

Name: lolD [C]

Synonym: Hbut_1410

Alternate gene names: 124028259

Gene position: 1412133-1412828 (Clockwise)

Preceding gene: 124028258

Following gene: 124028260

Centisome position: 84.7

GC content: 59.05

Gene sequence:

>696_bases
TTGACCGAGCCCATACTAGTGCTGGACAATGTGTGGAAACGTATCGCAGGCACAGCTGTGCTCCGCGGCGTGAGCCTCGA
GGCCCGCGCTGGCTGGCTTATAGTTGTGCGCGGAAGGAGCGGTATGGAGAAAACCACCCTCGCGAGGATAGCTGTGCTCC
TCGACGTACCCGACCAGGGCACGGTCATACTGCTTGGAAGGAGGATGGAGAGCCTAGGCGACTCTACACGGGCCAAGCTT
CGCCTCAGATACATAGGCTACGTAGACCAGTTCTACACCCTCGTAGAGCACCTCACAGTATGGGAGAACGTGGAGCTGCC
CCTGCGCCTCATGGGCATACCCCGGAGCGAGCGCGCCGCGAGGGTGAGAGAGGCAATACGCCTCATAGGCCTTGAGGAGC
GCAAGCCAGGCCAGCTCACTGGTGGGCAGAGACAACGCGTAGCCATAGCACGAGCGCTAGCAAAGAAGCCCCGGCTGATA
ATAGCTGACGAACCCTTCTCGAACCTCGACCAGGAGGCCGAAGAGCAGGTCCTCGAAGCACTGAGGAGCCATGCCAGAGA
GGGTAACGCCGTGATCATAACCGCTAAGGACCTCCTCCGGGACTATCGAGCAGTCCACGACTACACATTATCCAGTGGCA
TCCTCACTCCCACCGCACAATGTGGAACAAGAAAAACTGTCCCTGCCACCAGATAA

Upstream 100 bases:

>100_bases
CATAGAGCTAGAAAGGCTTCTCCAGGAGCTAAGCCTAATCTACAACACAGTCATAGTCCAAGCATACACCTACACCTAGG
CCTCAGAGGGCTGATGTTCC

Downstream 100 bases:

>100_bases
TCCACCACGGAGGGGGTTAGCCTGCGGCTAGTAAGCCTGGAGATGTTGTTGCAACTGTGCTAGCTGGTGGCACAGTGTGC
GCCGCGTGTTTCTCCTCATG

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTEPILVLDNVWKRIAGTAVLRGVSLEARAGWLIVVRGRSGMEKTTLARIAVLLDVPDQGTVILLGRRMESLGDSTRAKL
RLRYIGYVDQFYTLVEHLTVWENVELPLRLMGIPRSERAARVREAIRLIGLEERKPGQLTGGQRQRVAIARALAKKPRLI
IADEPFSNLDQEAEEQVLEALRSHAREGNAVIITAKDLLRDYRAVHDYTLSSGILTPTAQCGTRKTVPATR

Sequences:

>Translated_231_residues
MTEPILVLDNVWKRIAGTAVLRGVSLEARAGWLIVVRGRSGMEKTTLARIAVLLDVPDQGTVILLGRRMESLGDSTRAKL
RLRYIGYVDQFYTLVEHLTVWENVELPLRLMGIPRSERAARVREAIRLIGLEERKPGQLTGGQRQRVAIARALAKKPRLI
IADEPFSNLDQEAEEQVLEALRSHAREGNAVIITAKDLLRDYRAVHDYTLSSGILTPTAQCGTRKTVPATR
>Mature_230_residues
TEPILVLDNVWKRIAGTAVLRGVSLEARAGWLIVVRGRSGMEKTTLARIAVLLDVPDQGTVILLGRRMESLGDSTRAKLR
LRYIGYVDQFYTLVEHLTVWENVELPLRLMGIPRSERAARVREAIRLIGLEERKPGQLTGGQRQRVAIARALAKKPRLII
ADEPFSNLDQEAEEQVLEALRSHAREGNAVIITAKDLLRDYRAVHDYTLSSGILTPTAQCGTRKTVPATR

Specific function: Part Of The Abc Transporter Complex Lolcde Involved In The Translocation Of Mature Outer Membrane-Directed Lipoproteins, From The Inner Membrane To The Periplasmic Chaperone, Lola. Responsible For The Formation Of The Lola-Lipoprotein Complex In An ATP-De

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4505771, Length=194, Percent_Identity=35.0515463917526, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI9961250, Length=191, Percent_Identity=31.413612565445, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI9961252, Length=194, Percent_Identity=35.0515463917526, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI42490749, Length=203, Percent_Identity=32.512315270936, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI42741659, Length=189, Percent_Identity=32.2751322751323, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI46592964, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592956, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592915, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592971, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI255708477, Length=220, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592978, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592898, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI156105685, Length=191, Percent_Identity=34.5549738219895, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI21536378, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI27262624, Length=212, Percent_Identity=25.9433962264151, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI27262626, Length=212, Percent_Identity=25.9433962264151, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI148612844, Length=187, Percent_Identity=31.5508021390374, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI153792144, Length=167, Percent_Identity=24.5508982035928, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150417984, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI21536376, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27436953, Length=209, Percent_Identity=24.4019138755981, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI27477115, Length=182, Percent_Identity=25.8241758241758, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=36.8932038834951, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1787105, Length=181, Percent_Identity=39.7790055248619, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788225, Length=199, Percent_Identity=37.6884422110553, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87081709, Length=174, Percent_Identity=39.0804597701149, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786398, Length=165, Percent_Identity=41.8181818181818, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787370, Length=187, Percent_Identity=37.9679144385027, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786703, Length=184, Percent_Identity=37.5, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081791, Length=198, Percent_Identity=35.3535353535354, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787029, Length=195, Percent_Identity=36.9230769230769, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788644, Length=212, Percent_Identity=33.4905660377358, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788761, Length=182, Percent_Identity=37.3626373626374, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790467, Length=194, Percent_Identity=36.5979381443299, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789672, Length=199, Percent_Identity=33.6683417085427, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787089, Length=181, Percent_Identity=35.9116022099448, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=33.1730769230769, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789891, Length=188, Percent_Identity=37.2340425531915, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787712, Length=194, Percent_Identity=32.9896907216495, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1789032, Length=185, Percent_Identity=32.4324324324324, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082267, Length=173, Percent_Identity=36.4161849710983, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=33.1775700934579, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788506, Length=197, Percent_Identity=32.994923857868, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786872, Length=198, Percent_Identity=34.8484848484849, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788450, Length=234, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787500, Length=195, Percent_Identity=33.8461538461538, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI145693107, Length=183, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790544, Length=217, Percent_Identity=31.3364055299539, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789962, Length=186, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790534, Length=186, Percent_Identity=30.6451612903226, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994943, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=31.858407079646, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786698, Length=196, Percent_Identity=26.0204081632653, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87081782, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786253, Length=182, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787758, Length=166, Percent_Identity=31.3253012048193, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787164, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787547, Length=175, Percent_Identity=27.4285714285714, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=188, Percent_Identity=33.5106382978723, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788897, Length=188, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788165, Length=200, Percent_Identity=30.5, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790525, Length=237, Percent_Identity=24.8945147679325, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787759, Length=226, Percent_Identity=31.858407079646, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI48994883, Length=211, Percent_Identity=30.3317535545024, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786345, Length=205, Percent_Identity=29.7560975609756, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789991, Length=213, Percent_Identity=26.7605633802817, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87082064, Length=184, Percent_Identity=30.4347826086957, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788053, Length=174, Percent_Identity=31.6091954022989, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=215, Percent_Identity=23.7209302325581, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789864, Length=240, Percent_Identity=25.4166666666667, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367384, Length=215, Percent_Identity=26.9767441860465, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1787143, Length=183, Percent_Identity=32.7868852459016, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193202349, Length=188, Percent_Identity=35.1063829787234, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193211015, Length=187, Percent_Identity=32.0855614973262, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71996809, Length=187, Percent_Identity=32.0855614973262, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193211017, Length=187, Percent_Identity=32.0855614973262, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17541710, Length=196, Percent_Identity=34.6938775510204, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17552010, Length=219, Percent_Identity=30.1369863013699, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=191, Percent_Identity=35.0785340314136, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=189, Percent_Identity=32.2751322751323, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71984940, Length=212, Percent_Identity=33.4905660377358, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=188, Percent_Identity=31.9148936170213, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=197, Percent_Identity=28.4263959390863, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17569145, Length=206, Percent_Identity=35.4368932038835, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=200, Percent_Identity=34, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=187, Percent_Identity=31.0160427807487, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=109, Percent_Identity=41.2844036697248, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=108, Percent_Identity=40.7407407407407, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=193, Percent_Identity=32.6424870466321, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539902, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=182, Percent_Identity=29.1208791208791, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653245, Length=205, Percent_Identity=31.219512195122, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666092, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641565, Length=183, Percent_Identity=32.2404371584699, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17136662, Length=189, Percent_Identity=30.6878306878307, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24659289, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=181, Percent_Identity=30.3867403314917, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136592, Length=192, Percent_Identity=30.7291666666667, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574533, Length=218, Percent_Identity=28.4403669724771, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397593, Length=175, Percent_Identity=36.5714285714286, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25808; Mature: 25677

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPILVLDNVWKRIAGTAVLRGVSLEARAGWLIVVRGRSGMEKTTLARIAVLLDVPDQG
CCCCEEHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHHHHEEEEEECCCCC
TVILLGRRMESLGDSTRAKLRLRYIGYVDQFYTLVEHLTVWENVELPLRLMGIPRSERAA
CEEEEECHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
RVREAIRLIGLEERKPGQLTGGQRQRVAIARALAKKPRLIIADEPFSNLDQEAEEQVLEA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
LRSHAREGNAVIITAKDLLRDYRAVHDYTLSSGILTPTAQCGTRKTVPATR
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPILVLDNVWKRIAGTAVLRGVSLEARAGWLIVVRGRSGMEKTTLARIAVLLDVPDQG
CCCEEHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHHHHEEEEEECCCCC
TVILLGRRMESLGDSTRAKLRLRYIGYVDQFYTLVEHLTVWENVELPLRLMGIPRSERAA
CEEEEECHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
RVREAIRLIGLEERKPGQLTGGQRQRVAIARALAKKPRLIIADEPFSNLDQEAEEQVLEA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
LRSHAREGNAVIITAKDLLRDYRAVHDYTLSSGILTPTAQCGTRKTVPATR
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]