Click here to switch to the map view.

The map label for this gene is cysS [H]

Identifier: 124028047

GI number: 124028047

Start: 1195785

End: 1197257

Strand: Reverse

Name: cysS [H]

Synonym: Hbut_1188

Alternate gene names: 124028047

Gene position: 1197257-1195785 (Counterclockwise)

Preceding gene: 124028053

Following gene: 124028045

Centisome position: 71.81

GC content: 52.89

Gene sequence:

>1473_bases
GTGCAGAACTACCCCGTACTAAGCTACATAGAACTACCTCCCATACGGGTCCGTAACACATTTGGAGGTAAACTTGAGGA
GTTTAAGCCCCTAAGGCCCGGCTTAGTGCGCATGTATGTCTGCGGCCCAACAGTCTACGACTACACACACCTCGGCCATG
CTAGAACCTACGTGGCATTCGATGCCATCAAGAGGTATCTGAGGTTAAGAGGCTACAATGTCTACCATGTACAGAACATA
ACAGATATCGATGACAAGATTATCAACCGAGCACGTGAGGAGGGTAAGGACTGGCGCGAGATAGTCGAGACATACGCTAA
GGACTACTTTGAGGGGCTCCGCGCGCTCCGCATAAAGATAGACATGCATCCCCGCGTCACTAGCCATATACGCGAGATAA
TAGAGTTCATAGAAGGTCTCATAGACAAGGGCTACGCCTACGTAGCGCCAAGCGGCAGCGTATACTTCGAGGTAGACAAG
TATCCAGACTATGGAAGGCTTAGCGGTCGCTTCCACCCCGAGGAGTGGCGCCAGGAGGAGGACGTGCTAAAGGAGAAGAA
GAACCCATACGACTTCGCTCTCTGGAAGGCGTGGAAGCCGGGCGAGCCATACTGGGAGGCGCCCTGGGGCCGGGGGAGGC
CGGGCTGGCACATAGAGTGCAGCGTAATGGCATCAAGGTATCTTGGAGACCAATTCGACATACATGGTGGCGGCCAGGAC
CTCATATTCCCGCACCACGAGAACGAGCGAGCCCAGAGCGAGGCATACTTTGGCAAGAAGCCCTGGGTGAGATACTGGCT
GCACACGGGCTACCTCACAATACGCGGCGAAAAAATGAGCAAGAGTCTAGGCAACATTATACCGCTAAGAGAGGCGTTGA
AGAAGTGGAGCCCCGAGACGCTCCGCCTCTGGATACTAAGCGCCCACTATAGAACACAGTTAGACTTCTCTGAGGAATCG
CTAGAGCAGGCAAAAGCAAACCTCCGAAGGCTGCGTGGGGCCCTACAAGGCCTACAGAGGATCATCGAGGAGGTAGACCC
CCAGTCAAGGCTAGGTGATAGCGAAGCAAAGCTTGTCAACACAGTGCTGACGCTCTACAAGGAGTTCCACGAGGCCATGA
GCAATGACTTCAATACTTCCCGCGCGCTAGCAGCAGCGCTAAAGCTCGTAAAGACTGTTAACGCCGAAATTCTGCCAGCA
GAAAACTATACAGCAGCCATCCTAGCCTACAGGACACTACTAGAGTTCAACGAGGTATTCGCAGTGCTCGACGACATTGT
ATATGGTGTAGCTCAACAAGCCCAAAAGCTGGTCGGTAAGCTCGTAGACCTCATAGTTAAGGTCAGAGCCGAGCTTAGGG
CGAGAAAGATGTACGAGCTGGCAGACAACATTCGGGCAGAACTCGGAGAGCTAGGCATAAAGCTCTATGATTATCCTGGA
GGCAAAACTACTTGGAGATTTGAGGAAGGCTAA

Upstream 100 bases:

>100_bases
CGGCAGCTTCACCTCTTTTACACCCGTGGAAGAGTTCAGCGTTAGAGTTTTATGCAGGTTTCCAGGGCCACCACTCCACG
CCTAGGGGCGTGAGACTATT

Downstream 100 bases:

>100_bases
TAACTATATTTGCCCCCTTTCTCCTAGCGGCTTCAAGGTCGAGTCTCCTAAGTGCGCTCCTCAGGGCCTCTTCCATAGCT
TCACTGGCTGTGCCTATATC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MQNYPVLSYIELPPIRVRNTFGGKLEEFKPLRPGLVRMYVCGPTVYDYTHLGHARTYVAFDAIKRYLRLRGYNVYHVQNI
TDIDDKIINRAREEGKDWREIVETYAKDYFEGLRALRIKIDMHPRVTSHIREIIEFIEGLIDKGYAYVAPSGSVYFEVDK
YPDYGRLSGRFHPEEWRQEEDVLKEKKNPYDFALWKAWKPGEPYWEAPWGRGRPGWHIECSVMASRYLGDQFDIHGGGQD
LIFPHHENERAQSEAYFGKKPWVRYWLHTGYLTIRGEKMSKSLGNIIPLREALKKWSPETLRLWILSAHYRTQLDFSEES
LEQAKANLRRLRGALQGLQRIIEEVDPQSRLGDSEAKLVNTVLTLYKEFHEAMSNDFNTSRALAAALKLVKTVNAEILPA
ENYTAAILAYRTLLEFNEVFAVLDDIVYGVAQQAQKLVGKLVDLIVKVRAELRARKMYELADNIRAELGELGIKLYDYPG
GKTTWRFEEG

Sequences:

>Translated_490_residues
MQNYPVLSYIELPPIRVRNTFGGKLEEFKPLRPGLVRMYVCGPTVYDYTHLGHARTYVAFDAIKRYLRLRGYNVYHVQNI
TDIDDKIINRAREEGKDWREIVETYAKDYFEGLRALRIKIDMHPRVTSHIREIIEFIEGLIDKGYAYVAPSGSVYFEVDK
YPDYGRLSGRFHPEEWRQEEDVLKEKKNPYDFALWKAWKPGEPYWEAPWGRGRPGWHIECSVMASRYLGDQFDIHGGGQD
LIFPHHENERAQSEAYFGKKPWVRYWLHTGYLTIRGEKMSKSLGNIIPLREALKKWSPETLRLWILSAHYRTQLDFSEES
LEQAKANLRRLRGALQGLQRIIEEVDPQSRLGDSEAKLVNTVLTLYKEFHEAMSNDFNTSRALAAALKLVKTVNAEILPA
ENYTAAILAYRTLLEFNEVFAVLDDIVYGVAQQAQKLVGKLVDLIVKVRAELRARKMYELADNIRAELGELGIKLYDYPG
GKTTWRFEEG
>Mature_490_residues
MQNYPVLSYIELPPIRVRNTFGGKLEEFKPLRPGLVRMYVCGPTVYDYTHLGHARTYVAFDAIKRYLRLRGYNVYHVQNI
TDIDDKIINRAREEGKDWREIVETYAKDYFEGLRALRIKIDMHPRVTSHIREIIEFIEGLIDKGYAYVAPSGSVYFEVDK
YPDYGRLSGRFHPEEWRQEEDVLKEKKNPYDFALWKAWKPGEPYWEAPWGRGRPGWHIECSVMASRYLGDQFDIHGGGQD
LIFPHHENERAQSEAYFGKKPWVRYWLHTGYLTIRGEKMSKSLGNIIPLREALKKWSPETLRLWILSAHYRTQLDFSEES
LEQAKANLRRLRGALQGLQRIIEEVDPQSRLGDSEAKLVNTVLTLYKEFHEAMSNDFNTSRALAAALKLVKTVNAEILPA
ENYTAAILAYRTLLEFNEVFAVLDDIVYGVAQQAQKLVGKLVDLIVKVRAELRARKMYELADNIRAELGELGIKLYDYPG
GKTTWRFEEG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=508, Percent_Identity=35.4330708661417, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI10835051, Length=428, Percent_Identity=35.0467289719626, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI62240992, Length=428, Percent_Identity=35.0467289719626, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI21269877, Length=428, Percent_Identity=35.0467289719626, Blast_Score=232, Evalue=8e-61,
Organism=Homo sapiens, GI303304987, Length=428, Percent_Identity=35.0467289719626, Blast_Score=231, Evalue=8e-61,
Organism=Escherichia coli, GI1786737, Length=479, Percent_Identity=44.4676409185804, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17509795, Length=448, Percent_Identity=31.6964285714286, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17509797, Length=448, Percent_Identity=31.6964285714286, Blast_Score=214, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6324082, Length=412, Percent_Identity=35.9223300970874, Blast_Score=229, Evalue=6e-61,
Organism=Drosophila melanogaster, GI19922218, Length=508, Percent_Identity=36.6141732283465, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI19922364, Length=320, Percent_Identity=40.9375, Blast_Score=219, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56980; Mature: 56980

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00226 IF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNYPVLSYIELPPIRVRNTFGGKLEEFKPLRPGLVRMYVCGPTVYDYTHLGHARTYVAF
CCCCCEEEEEECCCEEEECCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHCCCHHHHHHH
DAIKRYLRLRGYNVYHVQNITDIDDKIINRAREEGKDWREIVETYAKDYFEGLRALRIKI
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEE
DMHPRVTSHIREIIEFIEGLIDKGYAYVAPSGSVYFEVDKYPDYGRLSGRFHPEEWRQEE
ECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHCCHH
DVLKEKKNPYDFALWKAWKPGEPYWEAPWGRGRPGWHIECSVMASRYLGDQFDIHGGGQD
HHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCCCCC
LIFPHHENERAQSEAYFGKKPWVRYWLHTGYLTIRGEKMSKSLGNIIPLREALKKWSPET
EECCCCCCCHHHHHHHCCCCCHHHHHEECCEEEEECHHHHHHHCCHHHHHHHHHHCCCCE
LRLWILSAHYRTQLDFSEESLEQAKANLRRLRGALQGLQRIIEEVDPQSRLGDSEAKLVN
EEEEEEEHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
TVLTLYKEFHEAMSNDFNTSRALAAALKLVKTVNAEILPAENYTAAILAYRTLLEFNEVF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHH
AVLDDIVYGVAQQAQKLVGKLVDLIVKVRAELRARKMYELADNIRAELGELGIKLYDYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GKTTWRFEEG
CCEEEEECCC
>Mature Secondary Structure
MQNYPVLSYIELPPIRVRNTFGGKLEEFKPLRPGLVRMYVCGPTVYDYTHLGHARTYVAF
CCCCCEEEEEECCCEEEECCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHCCCHHHHHHH
DAIKRYLRLRGYNVYHVQNITDIDDKIINRAREEGKDWREIVETYAKDYFEGLRALRIKI
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEE
DMHPRVTSHIREIIEFIEGLIDKGYAYVAPSGSVYFEVDKYPDYGRLSGRFHPEEWRQEE
ECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHCCHH
DVLKEKKNPYDFALWKAWKPGEPYWEAPWGRGRPGWHIECSVMASRYLGDQFDIHGGGQD
HHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCCCCC
LIFPHHENERAQSEAYFGKKPWVRYWLHTGYLTIRGEKMSKSLGNIIPLREALKKWSPET
EECCCCCCCHHHHHHHCCCCCHHHHHEECCEEEEECHHHHHHHCCHHHHHHHHHHCCCCE
LRLWILSAHYRTQLDFSEESLEQAKANLRRLRGALQGLQRIIEEVDPQSRLGDSEAKLVN
EEEEEEEHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
TVLTLYKEFHEAMSNDFNTSRALAAALKLVKTVNAEILPAENYTAAILAYRTLLEFNEVF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHH
AVLDDIVYGVAQQAQKLVGKLVDLIVKVRAELRARKMYELADNIRAELGELGIKLYDYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GKTTWRFEEG
CCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA