Definition Hyperthermus butylicus DSM 5456 chromosome, complete genome.
Accession NC_008818
Length 1,667,163

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The map label for this gene is pan [H]

Identifier: 124028002

GI number: 124028002

Start: 1151483

End: 1152700

Strand: Direct

Name: pan [H]

Synonym: Hbut_1140

Alternate gene names: 124028002

Gene position: 1151483-1152700 (Clockwise)

Preceding gene: 124027996

Following gene: 124028006

Centisome position: 69.07

GC content: 53.2

Gene sequence:

>1218_bases
ATGCAGTACAGCGACGCCAATGACCATGAGGCTTACCTCCGGAAGTATATTCAACAGCTTGAGCGCAGGGTTCGCGAGTT
AGAAGCTGAACGCTCAGAGCTGCGCCGTGAGCTACGCCGCTACCGCATAGAGGTTGACAAGCTGCTAAGCCCACCGCTCA
TCGAGGCTGTTGTACTCAGTGTGCTCCCCGATGGCAGGGTCGTGGTGAAGAGTAGTACTGGACCAAACCTAGTGGTAAAC
GTCTCATCAAATGTTGACGTGTCAAAACTAGTGCCTGGAGCCTATGTAGCGTTAAACCAGCGTGGATCTACAATAGTTGA
GGTTCTACCGGAGCGCGAGGACCCCTACGTAAAGGCTATGGAGGTTGTTGACAGACCCAAGGTCACGTTCGACGATATTG
GTGGGCTAGAGGAGCAAAAGAGGGAGCTATACGAGGCTATAATTCTACCGCTAAAGAAGCCTGAGCTATTCCGTGAACTA
GGCATAGAGCCTCCAAAGGGCGTACTGCTCTACGGGCCTCCCGGATGTGGCAAAACACTACTCGCTAAGGCTGTTGCAAG
CATGACCAATGCAACCTTCATACGTGTTGTAGCATCAGAGTTTGTCCACAAGTACGTCGGTGAGGGCGCAAGGATTGTAA
GGGAGGTCTTCAAGCTTGCGAGGCGCAAGGCGCCATCAATAATATTCATAGACGAAATAGACGCCATTGCAGCCAAGAGG
ATTGATCTAGGGACGAGTGGTGAGAGGGAGATACAGAGAACGCTAATGCAACTCCTAGCAGAGCTAGACGGTTTCGACCC
CCTAGGCGACGTAAAGGTCATCGCAGCCACCAACCGTATCGACATACTTGACCCGGCACTGCTAAGGCCGGGCAGGTTTG
ACAGGTTAATCTACGTGCCGCCACCTGATGAGAAGGGGCGGCTCGAGATATTCAGAATACATACCCGCCGCATGAAGCTC
GGCGAGGACGTAGACCTTGCCTACCTCGCAAAGATCACTGAAGGTGCTACCGGCGCCGATATAAGGGCTATAGTGATGGA
GGCTGGCTACAACGCTCTACGTGCCGGCAGGAGGGTAGTAATGATGGAAGACTTCCTAGCAGCTGTTGAGAAGGTTATGA
AGAAGCGCCGCAGACCGTACGCCACGATGCCAGAATATCTTGACGAGGCTCCAACGCGTGCCACAACGTCTAGCGAGGCT
GCTGTGATGCATATCTAG

Upstream 100 bases:

>100_bases
GTGCTGTCAAGGGGCTAGTATCACCAGTGTAGTTACGAGCCGCAAACCATTATTTAGGCTTCATCCTATCTCTAATATAG
GTGCATGGTGGCGCTAGAGT

Downstream 100 bases:

>100_bases
CAGTTTCCTCCTCCTCACGGATTTTAGATAGGTAGACTCTACGGTAGCGCCTCCAAACCTCGCCCATACGTGCAATCATA
CGGTTCCACTCCTTATCACT

Product: proteasome-activating nucleotidase

Products: NA

Alternate protein names: PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MQYSDANDHEAYLRKYIQQLERRVRELEAERSELRRELRRYRIEVDKLLSPPLIEAVVLSVLPDGRVVVKSSTGPNLVVN
VSSNVDVSKLVPGAYVALNQRGSTIVEVLPEREDPYVKAMEVVDRPKVTFDDIGGLEEQKRELYEAIILPLKKPELFREL
GIEPPKGVLLYGPPGCGKTLLAKAVASMTNATFIRVVASEFVHKYVGEGARIVREVFKLARRKAPSIIFIDEIDAIAAKR
IDLGTSGEREIQRTLMQLLAELDGFDPLGDVKVIAATNRIDILDPALLRPGRFDRLIYVPPPDEKGRLEIFRIHTRRMKL
GEDVDLAYLAKITEGATGADIRAIVMEAGYNALRAGRRVVMMEDFLAAVEKVMKKRRRPYATMPEYLDEAPTRATTSSEA
AVMHI

Sequences:

>Translated_405_residues
MQYSDANDHEAYLRKYIQQLERRVRELEAERSELRRELRRYRIEVDKLLSPPLIEAVVLSVLPDGRVVVKSSTGPNLVVN
VSSNVDVSKLVPGAYVALNQRGSTIVEVLPEREDPYVKAMEVVDRPKVTFDDIGGLEEQKRELYEAIILPLKKPELFREL
GIEPPKGVLLYGPPGCGKTLLAKAVASMTNATFIRVVASEFVHKYVGEGARIVREVFKLARRKAPSIIFIDEIDAIAAKR
IDLGTSGEREIQRTLMQLLAELDGFDPLGDVKVIAATNRIDILDPALLRPGRFDRLIYVPPPDEKGRLEIFRIHTRRMKL
GEDVDLAYLAKITEGATGADIRAIVMEAGYNALRAGRRVVMMEDFLAAVEKVMKKRRRPYATMPEYLDEAPTRATTSSEA
AVMHI
>Mature_405_residues
MQYSDANDHEAYLRKYIQQLERRVRELEAERSELRRELRRYRIEVDKLLSPPLIEAVVLSVLPDGRVVVKSSTGPNLVVN
VSSNVDVSKLVPGAYVALNQRGSTIVEVLPEREDPYVKAMEVVDRPKVTFDDIGGLEEQKRELYEAIILPLKKPELFREL
GIEPPKGVLLYGPPGCGKTLLAKAVASMTNATFIRVVASEFVHKYVGEGARIVREVFKLARRKAPSIIFIDEIDAIAAKR
IDLGTSGEREIQRTLMQLLAELDGFDPLGDVKVIAATNRIDILDPALLRPGRFDRLIYVPPPDEKGRLEIFRIHTRRMKL
GEDVDLAYLAKITEGATGADIRAIVMEAGYNALRAGRRVVMMEDFLAAVEKVMKKRRRPYATMPEYLDEAPTRATTSSEA
AVMHI

Specific function: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereb

COG id: COG1222

COG function: function code O; ATP-dependent 26S proteasome regulatory subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI24430151, Length=365, Percent_Identity=48.7671232876712, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI24497435, Length=363, Percent_Identity=47.9338842975207, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI89064750, Length=368, Percent_Identity=46.4673913043478, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI5729991, Length=368, Percent_Identity=46.4673913043478, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI195539395, Length=360, Percent_Identity=47.5, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI24430155, Length=354, Percent_Identity=48.0225988700565, Blast_Score=325, Evalue=5e-89,
Organism=Homo sapiens, GI21361144, Length=375, Percent_Identity=45.3333333333333, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI4506209, Length=401, Percent_Identity=42.3940149625935, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI6005942, Length=227, Percent_Identity=48.4581497797357, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI157671927, Length=254, Percent_Identity=48.0314960629921, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI300192933, Length=254, Percent_Identity=47.6377952755905, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI45643125, Length=297, Percent_Identity=41.7508417508418, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI45643123, Length=297, Percent_Identity=41.7508417508418, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4507173, Length=249, Percent_Identity=45.7831325301205, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4505725, Length=224, Percent_Identity=45.0892857142857, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI229577436, Length=279, Percent_Identity=39.426523297491, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI7657689, Length=255, Percent_Identity=41.9607843137255, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI21327685, Length=255, Percent_Identity=41.9607843137255, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI5901990, Length=289, Percent_Identity=42.560553633218, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI24497618, Length=235, Percent_Identity=44.2553191489362, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI194018488, Length=262, Percent_Identity=44.2748091603053, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI14149767, Length=250, Percent_Identity=44, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI62177112, Length=250, Percent_Identity=44, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI153792536, Length=236, Percent_Identity=44.9152542372881, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI7019569, Length=230, Percent_Identity=40, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI11875211, Length=286, Percent_Identity=39.5104895104895, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI17865802, Length=249, Percent_Identity=39.7590361445783, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI40806170, Length=286, Percent_Identity=39.5104895104895, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI156564401, Length=282, Percent_Identity=37.9432624113475, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI310125282, Length=282, Percent_Identity=37.5886524822695, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI310125280, Length=272, Percent_Identity=38.2352941176471, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI31742536, Length=240, Percent_Identity=35, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI112789543, Length=240, Percent_Identity=35, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI226371754, Length=245, Percent_Identity=37.1428571428571, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI31377644, Length=233, Percent_Identity=38.1974248927039, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=49.2753623188406, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI64084766, Length=237, Percent_Identity=29.957805907173, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI116292174, Length=272, Percent_Identity=30.8823529411765, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1789568, Length=267, Percent_Identity=46.4419475655431, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17563250, Length=334, Percent_Identity=49.4011976047904, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17554786, Length=377, Percent_Identity=47.2148541114058, Blast_Score=330, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI25144278, Length=382, Percent_Identity=47.3821989528796, Blast_Score=330, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI25144281, Length=382, Percent_Identity=47.3821989528796, Blast_Score=330, Evalue=9e-91,
Organism=Caenorhabditis elegans, GI71987372, Length=369, Percent_Identity=45.7994579945799, Blast_Score=328, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI71987364, Length=369, Percent_Identity=45.7994579945799, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI17554784, Length=363, Percent_Identity=47.9338842975207, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17508701, Length=410, Percent_Identity=42.1951219512195, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17563248, Length=331, Percent_Identity=45.9214501510574, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17505546, Length=347, Percent_Identity=48.1268011527378, Blast_Score=297, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI17532375, Length=234, Percent_Identity=47.4358974358974, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17531535, Length=234, Percent_Identity=45.7264957264957, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71994521, Length=251, Percent_Identity=48.605577689243, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17508053, Length=234, Percent_Identity=45.2991452991453, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17537217, Length=236, Percent_Identity=46.6101694915254, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI25153574, Length=240, Percent_Identity=42.9166666666667, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17554264, Length=266, Percent_Identity=43.2330827067669, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193209502, Length=238, Percent_Identity=42.8571428571429, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI115534323, Length=277, Percent_Identity=42.5992779783394, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17562804, Length=251, Percent_Identity=40.2390438247012, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193206116, Length=236, Percent_Identity=41.1016949152542, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=41.1016949152542, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=236, Percent_Identity=41.1016949152542, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI86561515, Length=229, Percent_Identity=41.0480349344978, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25146157, Length=312, Percent_Identity=34.2948717948718, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17541224, Length=270, Percent_Identity=36.6666666666667, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541226, Length=270, Percent_Identity=36.6666666666667, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17560432, Length=234, Percent_Identity=38.8888888888889, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI133901662, Length=287, Percent_Identity=33.4494773519164, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI133901658, Length=287, Percent_Identity=33.4494773519164, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32563584, Length=231, Percent_Identity=40.6926406926407, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17508421, Length=231, Percent_Identity=40.6926406926407, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17570397, Length=133, Percent_Identity=39.8496240601504, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI32566590, Length=133, Percent_Identity=39.8496240601504, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71990294, Length=387, Percent_Identity=24.2894056847545, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324833, Length=359, Percent_Identity=48.7465181058496, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6320197, Length=325, Percent_Identity=51.0769230769231, Blast_Score=325, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6321390, Length=380, Percent_Identity=45.2631578947368, Blast_Score=319, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6324691, Length=314, Percent_Identity=47.7707006369427, Blast_Score=312, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6320602, Length=340, Percent_Identity=47.9411764705882, Blast_Score=309, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6322704, Length=311, Percent_Identity=47.588424437299, Blast_Score=299, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6323429, Length=278, Percent_Identity=46.7625899280576, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6320077, Length=228, Percent_Identity=50, Blast_Score=215, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6323736, Length=250, Percent_Identity=47.6, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320854, Length=255, Percent_Identity=45.0980392156863, Blast_Score=199, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324000, Length=238, Percent_Identity=47.4789915966387, Blast_Score=195, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6325281, Length=291, Percent_Identity=40.893470790378, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322994, Length=254, Percent_Identity=40.5511811023622, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321709, Length=285, Percent_Identity=39.2982456140351, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321465, Length=266, Percent_Identity=38.3458646616541, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6325183, Length=254, Percent_Identity=37.007874015748, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6325431, Length=247, Percent_Identity=40.080971659919, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319554, Length=287, Percent_Identity=36.5853658536585, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6320887, Length=253, Percent_Identity=38.7351778656126, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322651, Length=258, Percent_Identity=34.8837209302326, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19920408, Length=376, Percent_Identity=47.0744680851064, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24649446, Length=336, Percent_Identity=51.1904761904762, Blast_Score=339, Evalue=3e-93,
Organism=Drosophila melanogaster, GI18860063, Length=368, Percent_Identity=46.4673913043478, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361487, Length=379, Percent_Identity=44.3271767810026, Blast_Score=327, Evalue=9e-90,
Organism=Drosophila melanogaster, GI24640100, Length=360, Percent_Identity=48.0555555555556, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI17738151, Length=375, Percent_Identity=45.3333333333333, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24651451, Length=374, Percent_Identity=47.0588235294118, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17137738, Length=324, Percent_Identity=47.8395061728395, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI24663015, Length=360, Percent_Identity=46.3888888888889, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI28574878, Length=248, Percent_Identity=47.9838709677419, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24665814, Length=248, Percent_Identity=47.9838709677419, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17137560, Length=234, Percent_Identity=46.5811965811966, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI161076486, Length=234, Percent_Identity=46.5811965811966, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI161076488, Length=234, Percent_Identity=46.5811965811966, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI19921202, Length=270, Percent_Identity=42.962962962963, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281365776, Length=243, Percent_Identity=46.5020576131687, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24660075, Length=243, Percent_Identity=46.5020576131687, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI45552965, Length=243, Percent_Identity=46.5020576131687, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24658770, Length=247, Percent_Identity=45.748987854251, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24639391, Length=254, Percent_Identity=45.2755905511811, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24656825, Length=259, Percent_Identity=40.5405405405405, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24656820, Length=259, Percent_Identity=40.5405405405405, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24652279, Length=194, Percent_Identity=46.9072164948454, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281363136, Length=258, Percent_Identity=40.6976744186046, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI78707192, Length=258, Percent_Identity=40.6976744186046, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI18859657, Length=230, Percent_Identity=42.1739130434783, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24644145, Length=235, Percent_Identity=42.1276595744681, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21355121, Length=231, Percent_Identity=39.8268398268398, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571849, Length=262, Percent_Identity=38.9312977099237, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28571847, Length=262, Percent_Identity=38.9312977099237, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17864540, Length=303, Percent_Identity=35.6435643564356, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281360144, Length=236, Percent_Identity=39.4067796610169, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360140, Length=236, Percent_Identity=39.4067796610169, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360136, Length=236, Percent_Identity=39.4067796610169, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24644411, Length=236, Percent_Identity=39.4067796610169, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360146, Length=235, Percent_Identity=39.5744680851064, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360138, Length=235, Percent_Identity=39.5744680851064, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360142, Length=235, Percent_Identity=39.5744680851064, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21357333, Length=235, Percent_Identity=39.5744680851064, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24581396, Length=232, Percent_Identity=39.6551724137931, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573010, Length=275, Percent_Identity=36.7272727272727, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI20129423, Length=230, Percent_Identity=35.6521739130435, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45554047, Length=168, Percent_Identity=47.6190476190476, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI20129529, Length=236, Percent_Identity=35.1694915254237, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24639486, Length=248, Percent_Identity=35.4838709677419, Blast_Score=124, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005937
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 45501; Mature: 45501

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MQYSDANDHEAYLRKYIQQLERRVRELEAERSELRRELRRYRIEVDKLLSPPLIEAVVLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VLPDGRVVVKSSTGPNLVVNVSSNVDVSKLVPGAYVALNQRGSTIVEVLPEREDPYVKAM
HCCCCCEEEECCCCCEEEEEECCCCCHHHHCCCEEEEECCCCCCHHHCCCCCCCHHHHHH
EVVDRPKVTFDDIGGLEEQKRELYEAIILPLKKPELFRELGIEPPKGVLLYGPPGCGKTL
HHHCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHH
LAKAVASMTNATFIRVVASEFVHKYVGEGARIVREVFKLARRKAPSIIFIDEIDAIAAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
IDLGTSGEREIQRTLMQLLAELDGFDPLGDVKVIAATNRIDILDPALLRPGRFDRLIYVP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCEEEEEC
PPDEKGRLEIFRIHTRRMKLGEDVDLAYLAKITEGATGADIRAIVMEAGYNALRAGRRVV
CCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHCCEEE
MMEDFLAAVEKVMKKRRRPYATMPEYLDEAPTRATTSSEAAVMHI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MQYSDANDHEAYLRKYIQQLERRVRELEAERSELRRELRRYRIEVDKLLSPPLIEAVVLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VLPDGRVVVKSSTGPNLVVNVSSNVDVSKLVPGAYVALNQRGSTIVEVLPEREDPYVKAM
HCCCCCEEEECCCCCEEEEEECCCCCHHHHCCCEEEEECCCCCCHHHCCCCCCCHHHHHH
EVVDRPKVTFDDIGGLEEQKRELYEAIILPLKKPELFRELGIEPPKGVLLYGPPGCGKTL
HHHCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHH
LAKAVASMTNATFIRVVASEFVHKYVGEGARIVREVFKLARRKAPSIIFIDEIDAIAAKR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
IDLGTSGEREIQRTLMQLLAELDGFDPLGDVKVIAATNRIDILDPALLRPGRFDRLIYVP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCEEEEEC
PPDEKGRLEIFRIHTRRMKLGEDVDLAYLAKITEGATGADIRAIVMEAGYNALRAGRRVV
CCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHCCEEE
MMEDFLAAVEKVMKKRRRPYATMPEYLDEAPTRATTSSEAAVMHI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]