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The map label for this gene is speH [H]

Identifier: 124027942

GI number: 124027942

Start: 1091243

End: 1091638

Strand: Direct

Name: speH [H]

Synonym: Hbut_1074

Alternate gene names: 124027942

Gene position: 1091243-1091638 (Clockwise)

Preceding gene: 124027938

Following gene: 124027946

Centisome position: 65.46

GC content: 53.54

Gene sequence:

>396_bases
ATGAAGACTATAGCAACTATACGGCCAAGGCCTAAGCCTGCTGAGGGCGAGCCAAGAGTATACGGCATGCACGTGTTCGG
CAACCTCTACGAGTGCAACGTAGAGACTCTCCGTGACGAGAAGCGGCTCCGCGAAATAGTCGTCGAGGCTGCCAAGGTTG
GCAACATGACACTGCTAGATGTCAAGAGCTGGAAGATCGGGGAAGGCGTTAGCGTAGTAGCGATAGTCCTTGAAAGTCAC
ATAACAATCCATACCTGGCCGGAGTACGCCTTTGCCACAGTTGACGTTTACAGCTGCGGCAAGCACACCAACCCGGAGAA
GGCCTTCAACTACATAGTCTTCGCGCTCGGCGCTAAGAGGGTTGAAAGGCAGACCGCTACTAGGCATTTGGAATAG

Upstream 100 bases:

>100_bases
GGCAGGAGGGTCTTCGCGTTATACAACCATTACAAGGCTGAGGAGGGGGGGTAACCCTTAAAGCTGATGCATAGAAGTCC
CCTCCCCCTCGGTGGGGGGT

Downstream 100 bases:

>100_bases
GATTCCCCTACCTCAAAACGTTTTTATAGTAGGTTGTTAGGCATACTACCCCCCTCCTTCCCTCCTACAGCTGCCGAGCC
TATCATAGGCCTCGGCTAGT

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKTIATIRPRPKPAEGEPRVYGMHVFGNLYECNVETLRDEKRLREIVVEAAKVGNMTLLDVKSWKIGEGVSVVAIVLESH
ITIHTWPEYAFATVDVYSCGKHTNPEKAFNYIVFALGAKRVERQTATRHLE

Sequences:

>Translated_131_residues
MKTIATIRPRPKPAEGEPRVYGMHVFGNLYECNVETLRDEKRLREIVVEAAKVGNMTLLDVKSWKIGEGVSVVAIVLESH
ITIHTWPEYAFATVDVYSCGKHTNPEKAFNYIVFALGAKRVERQTATRHLE
>Mature_131_residues
MKTIATIRPRPKPAEGEPRVYGMHVFGNLYECNVETLRDEKRLREIVVEAAKVGNMTLLDVKSWKIGEGVSVVAIVLESH
ITIHTWPEYAFATVDVYSCGKHTNPEKAFNYIVFALGAKRVERQTATRHLE

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 14840; Mature: 14840

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIATIRPRPKPAEGEPRVYGMHVFGNLYECNVETLRDEKRLREIVVEAAKVGNMTLLD
CCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEE
VKSWKIGEGVSVVAIVLESHITIHTWPEYAFATVDVYSCGKHTNPEKAFNYIVFALGAKR
ECCCCCCCCCEEEEEEECCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHEECCHHH
VERQTATRHLE
HHHHHHHHCCC
>Mature Secondary Structure
MKTIATIRPRPKPAEGEPRVYGMHVFGNLYECNVETLRDEKRLREIVVEAAKVGNMTLLD
CCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEE
VKSWKIGEGVSVVAIVLESHITIHTWPEYAFATVDVYSCGKHTNPEKAFNYIVFALGAKR
ECCCCCCCCCEEEEEEECCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHEECCHHH
VERQTATRHLE
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]