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The map label for this gene is upp [H]

Identifier: 124027883

GI number: 124027883

Start: 1025904

End: 1026569

Strand: Reverse

Name: upp [H]

Synonym: Hbut_1012

Alternate gene names: 124027883

Gene position: 1026569-1025904 (Counterclockwise)

Preceding gene: 124027884

Following gene: 124027874

Centisome position: 61.58

GC content: 62.16

Gene sequence:

>666_bases
GTGAGCCGTCTAGAGCTACACGTCGCTGAGAATCCTGCCCTCCAACGCATCCTCCTAGAACTGCGTGACGAGCATACCGA
GCCGTGGAGATTCCGGGAGCTGCTGAGGCTCGCCGGGATACTCCTCGGCTACGAGGCTGCCAGGTTCCTCCCATCTAGAC
GGGATACTGTGAGAACCCCCCTTGGCGCCACAGCTTCCGCTGTACGGGTAGCTGATGAAGAGCTTGTGGTGGTTGCTGTT
CTCCGCGCGGCAGCACCCATGGCTATGGGGCTCCTCGAACTTTACCCCCGCGCCGTGCTAGGCTTCGCCGCCGCGACGAG
GCTCGAGGATACGGGGAGGCAGCAGGAAGGTAGGCTAGTGTTCGACGTGGAGGTACCCTACTGGAGGGTGCCCCCAGTGA
AGGATAAGACCGTCATCGCCGTGGACCCCATGCTAGCTACGGGAAGCACATTGTCGAGGATCGTGGCCCGCCTAGAGCGG
GAAGGCGCCAAGAGAATCGTGGTGGTTTCCCTGATAGCTACTCGGGAGGGGCTAGAGACACTCCGCGAAGCCGTGAAGGG
GGAAATAGCTGTTGTGGTCGGAGCCGTGGACCCAGAGCTGAACGAGAAGGGCTTCATAGTCCCCGGCCTGGGCGATGCCG
GAGACCGCAGCTTCGGTGAAGCCTAG

Upstream 100 bases:

>100_bases
ACGGTCTCGTGGAGGCCCTCTGCCGGTCCGGGATGCAGCTAGGCTAGCACAGACTTGATAAACCCTGGACGCCCCGGTAG
CGGCCCCATCTGGGTGGCCG

Downstream 100 bases:

>100_bases
CTTTTTGTCTCTTTCTCCTGCTTCTCCCTCAGCATCTTCTCCACTTTCGCCAGAAACCTCTCCGTGTTCACGATGTAGCG
CTCGTGCTCACCCTCACCCA

Product: Uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSRLELHVAENPALQRILLELRDEHTEPWRFRELLRLAGILLGYEAARFLPSRRDTVRTPLGATASAVRVADEELVVVAV
LRAAAPMAMGLLELYPRAVLGFAAATRLEDTGRQQEGRLVFDVEVPYWRVPPVKDKTVIAVDPMLATGSTLSRIVARLER
EGAKRIVVVSLIATREGLETLREAVKGEIAVVVGAVDPELNEKGFIVPGLGDAGDRSFGEA

Sequences:

>Translated_221_residues
MSRLELHVAENPALQRILLELRDEHTEPWRFRELLRLAGILLGYEAARFLPSRRDTVRTPLGATASAVRVADEELVVVAV
LRAAAPMAMGLLELYPRAVLGFAAATRLEDTGRQQEGRLVFDVEVPYWRVPPVKDKTVIAVDPMLATGSTLSRIVARLER
EGAKRIVVVSLIATREGLETLREAVKGEIAVVVGAVDPELNEKGFIVPGLGDAGDRSFGEA
>Mature_220_residues
SRLELHVAENPALQRILLELRDEHTEPWRFRELLRLAGILLGYEAARFLPSRRDTVRTPLGATASAVRVADEELVVVAVL
RAAAPMAMGLLELYPRAVLGFAAATRLEDTGRQQEGRLVFDVEVPYWRVPPVKDKTVIAVDPMLATGSTLSRIVARLERE
GAKRIVVVSLIATREGLETLREAVKGEIAVVVGAVDPELNEKGFIVPGLGDAGDRSFGEA

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Escherichia coli, GI87082118, Length=212, Percent_Identity=32.5471698113208, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321920, Length=181, Percent_Identity=30.3867403314917, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550449, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573516, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573514, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573512, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR005765 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24167; Mature: 24036

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLELHVAENPALQRILLELRDEHTEPWRFRELLRLAGILLGYEAARFLPSRRDTVRTP
CCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
LGATASAVRVADEELVVVAVLRAAAPMAMGLLELYPRAVLGFAAATRLEDTGRQQEGRLV
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FDVEVPYWRVPPVKDKTVIAVDPMLATGSTLSRIVARLEREGAKRIVVVSLIATREGLET
EEECCCEEECCCCCCCEEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
LREAVKGEIAVVVGAVDPELNEKGFIVPGLGDAGDRSFGEA
HHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLELHVAENPALQRILLELRDEHTEPWRFRELLRLAGILLGYEAARFLPSRRDTVRTP
CCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
LGATASAVRVADEELVVVAVLRAAAPMAMGLLELYPRAVLGFAAATRLEDTGRQQEGRLV
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FDVEVPYWRVPPVKDKTVIAVDPMLATGSTLSRIVARLEREGAKRIVVVSLIATREGLET
EEECCCEEECCCCCCCEEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
LREAVKGEIAVVVGAVDPELNEKGFIVPGLGDAGDRSFGEA
HHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA