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The map label for this gene is pfpI [H]

Identifier: 124027868

GI number: 124027868

Start: 1012360

End: 1012944

Strand: Reverse

Name: pfpI [H]

Synonym: Hbut_0996

Alternate gene names: 124027868

Gene position: 1012944-1012360 (Counterclockwise)

Preceding gene: 124027869

Following gene: 124027863

Centisome position: 60.76

GC content: 57.78

Gene sequence:

>585_bases
GTGCCCCGCGCTCTCTTCATAGTAGAGCCCGACTTTGACGACCTCGAATTCTTCTACGCGTACCACCGTCTCCTCGAAGA
AGGCTTCGAAATCGACATAGCGTCTCACGCCAAGTACAGCGACGTGCCCCGCTACGACCCCCAAACAGGGAGGCTAGAAC
CCCGCCCGCTGAAGATAAAGGGCAAGAGGGGCTTCGAGGTTGAGGCTACGCTCAGCTACCGGGAGGCAGTGGAGAGGCTT
GACAGCTACGACGTCCTTGTAATCCCCGGCGGGAGGAGCCCGGAAAGGGCTAGGCAGCACCGAGAGGCAGTGGAGATAGC
TAGGAGGATGGCTGAGAAGGGTAAACCAATCATAGCCATATGTCACGGCCCACTACTCCTAGCCTCAGCTAGTGTCATCA
GGGGCCGTAGGGTTACAGGCTACCCAGGCATAAAGGACGATCTTGTGAACGCAGGCGCAGAATACGTTGATGCCGGCGCA
GTTCTAGATGGCAACATAGTCACTGTGAGGCACACAAGCAGCATGGGTGAGGGCTTCCGGCTATTCATACAGCTGCTCCG
CGAGAAAGGCCTGGCAAGGAGCTGA

Upstream 100 bases:

>100_bases
AGAAGGTTATGGCTGAGCTGCACCGGCTAAAGCTGAGGCTAACAACCACTCTGCCCCTAGACCTACACAAATAATCCACA
GTCATAAGGGGTGACCAGCT

Downstream 100 bases:

>100_bases
GCAGGGCCTGGCGTGCGTAGGTGTGGCGAGAGGGTGCTAGCAAAACACTACCCTTATTGTTTTTGTACCGTCTAGGCTAC
ACCTATCTTCTGTAGCCACT

Product: protease I

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MPRALFIVEPDFDDLEFFYAYHRLLEEGFEIDIASHAKYSDVPRYDPQTGRLEPRPLKIKGKRGFEVEATLSYREAVERL
DSYDVLVIPGGRSPERARQHREAVEIARRMAEKGKPIIAICHGPLLLASASVIRGRRVTGYPGIKDDLVNAGAEYVDAGA
VLDGNIVTVRHTSSMGEGFRLFIQLLREKGLARS

Sequences:

>Translated_194_residues
MPRALFIVEPDFDDLEFFYAYHRLLEEGFEIDIASHAKYSDVPRYDPQTGRLEPRPLKIKGKRGFEVEATLSYREAVERL
DSYDVLVIPGGRSPERARQHREAVEIARRMAEKGKPIIAICHGPLLLASASVIRGRRVTGYPGIKDDLVNAGAEYVDAGA
VLDGNIVTVRHTSSMGEGFRLFIQLLREKGLARS
>Mature_193_residues
PRALFIVEPDFDDLEFFYAYHRLLEEGFEIDIASHAKYSDVPRYDPQTGRLEPRPLKIKGKRGFEVEATLSYREAVERLD
SYDVLVIPGGRSPERARQHREAVEIARRMAEKGKPIIAICHGPLLLASASVIRGRRVTGYPGIKDDLVNAGAEYVDAGAV
LDGNIVTVRHTSSMGEGFRLFIQLLREKGLARS

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=131, Percent_Identity=38.9312977099237, Blast_Score=88, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653499, Length=169, Percent_Identity=30.1775147928994, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21767; Mature: 21636

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRALFIVEPDFDDLEFFYAYHRLLEEGFEIDIASHAKYSDVPRYDPQTGRLEPRPLKIK
CCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
GKRGFEVEATLSYREAVERLDSYDVLVIPGGRSPERARQHREAVEIARRMAEKGKPIIAI
CCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
CHGPLLLASASVIRGRRVTGYPGIKDDLVNAGAEYVDAGAVLDGNIVTVRHTSSMGEGFR
ECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHCCCCEECCCEEEEEECCCCCHHHH
LFIQLLREKGLARS
HHHHHHHHCCCCCC
>Mature Secondary Structure 
PRALFIVEPDFDDLEFFYAYHRLLEEGFEIDIASHAKYSDVPRYDPQTGRLEPRPLKIK
CCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
GKRGFEVEATLSYREAVERLDSYDVLVIPGGRSPERARQHREAVEIARRMAEKGKPIIAI
CCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
CHGPLLLASASVIRGRRVTGYPGIKDDLVNAGAEYVDAGAVLDGNIVTVRHTSSMGEGFR
ECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHCCCCEECCCEEEEEECCCCCHHHH
LFIQLLREKGLARS
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]